6-hydroxy-5-methoxy-3',4'-methylenedioxy-2'',2''-dimethylpyrano[5'',6'':7,8]isoflavone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 6-hydroxy-5-methoxy-3',4'-methylenedioxy-2'',2''-dimethylpyrano[5'',6'':7,8]isoflavone
• 英文别名: griffonianone B；3-(1,3-Benzodioxol-5-yl)-6-hydroxy-5-methoxy-8,8-dimethylpyrano[2,3-h]chromen-4-one
• 化学式: C₂₂H₁₈O₇
• 分子量: 394.381
• InChiKey: WWDGFJYGAQKSRX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  29
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  83.4
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  硫酸二甲酯 、 6-hydroxy-5-methoxy-3',4'-methylenedioxy-2'',2''-dimethylpyrano[5'',6'':7,8]isoflavone 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 生成 5-methoxydurmillone
  参考文献：
  名称：

  Further isoflavonoid metabolites from Millettia griffoniana (Bail)

  摘要：

  Three new isoflavonoids, griffonianone A (1), B (2) and C (4) were isolated from the root bark of Millettia griffoniama, along with the known maximaisoflavone G (5) and 7-hydroxy-6-methoxy-3',4'-methylenedioxyisoflavone (6). Their structures were assigned on the basis of spectroscopic data and chemical transformations. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(00)00400-3

文献信息

• Further isoflavonoid metabolites from Millettia griffoniana (Bail)
  作者：Emmanuel Yankep、J.Tanyi Mbafor、Z.Tanee Fomum、Christoph Steinbeck、Bernard Blaise Messanga、Barthelemy Nyasse、H. Budzikiewicz、Christof Lenz、Hans Schmickler

  DOI：10.1016/s0031-9422(00)00400-3

  日期：2001.2

  Three new isoflavonoids, griffonianone A (1), B (2) and C (4) were isolated from the root bark of Millettia griffoniama, along with the known maximaisoflavone G (5) and 7-hydroxy-6-methoxy-3',4'-methylenedioxyisoflavone (6). Their structures were assigned on the basis of spectroscopic data and chemical transformations. (C) 2001 Elsevier Science Ltd. All rights reserved.