cis-Atlanton | 32207-07-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: cis-Atlanton
• 英文别名: (E)-10,11-Dihydro-alpha-atlantone；(5Z)-2-methyl-6-(4-methylcyclohex-3-en-1-yl)hepta-2,5-dien-4-one
• CAS: 32207-07-1
• 化学式: C₁₅H₂₂O
• 分子量: 218.339
• InChiKey: OJEFBZMKKJTKKK-RAXLEYEMSA-N

物化性质

• 沸点：
  321.1±21.0 °C(Predicted)
• 密度：
  0.929±0.06 g/cm3(Predicted)
• 保留指数：
  1703;1703

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  cis-Atlanton 在 盐酸 、 palladium on activated charcoal 作用下， 以 乙醇 、 水 为溶剂， 反应 17.0h， 生成 2-methyl-6-p-tolylhept-2-en-4-one thiosemicarbazone
  参考文献：
  名称：

  Aromatization of (Z) and (E)-α-atlantones isolated from Cedrus atlantica essential oil followed by condensation with thiosemicarbazide: synthesis of new thiadiazolines derivatives

  摘要：

  Aromatization, using Pd/C (10%) of (Z) and (E)-alpha-atlantones isolated from Cedrus atlantica essential oil, followed by condensation with thiosemicarbazide gave novel 1,3,4-thiadiazolic derivatives by the introduction of new functional groups on the terpenic skeletons. After aromatization and thiosemicarbazide condensation, all products were obtained in good yields to give thiadiazolic compounds bearing new spiro carbons. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2015.11.103
• 作为产物：
  描述：

  3-甲基巴豆腈 在 zinc silver 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 苯 为溶剂， 反应 22.0h， 生成 cis-Atlanton
  参考文献：
  名称：

  Condensation des nitriles avec les organozinciques allyliques. Applications en serie terpenique

  摘要：

  DOI：

  10.1016/s0040-4020(01)91958-1

文献信息

• One-Pot Synthesis of β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds
  作者：Masaharu Sugiura、Yasuhiko Ashikari、Makoto Nakajima

  DOI：10.1021/acs.joc.5b01217

  日期：2015.9.4

  TiCl4-promoted aldol reaction of ketones as aldol acceptors followed by elimination of the titanoxy group from the Ti-aldolates affords β,β-disubstituted α,β-unsaturated carbonyl compounds in a one-pot procedure. The use of additives, such as DMF, N,N,N′,N′-tetramethylethylenediamine, and pyridine, in the elimination step was found to be important.

  TiCl 4促进的酮作为醛醇受体的醛醇缩醛反应，然后从Ti-醛醇酸酯中消除钛氧基，可以一锅法制得β，β-二取代的α，β-不饱和羰基化合物。发现在消除步骤中使用添加剂，例如DMF，N，N，N '，N'-四甲基乙二胺和吡啶是重要的。
• Adams,D.R. et al., Journal of the Chemical Society. Perkin transactions I, 1975, p. 1741 - 1743
  作者：Adams,D.R. et al.

  DOI：——

  日期：——
• PRO-FRAGRANCES
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP1171566A1

  公开（公告）日：2002-01-16
• US6551987B1
  申请人：——

  公开号：US6551987B1

  公开（公告）日：2003-04-22
• [EN] PRO-FRAGRANCES<br/>[FR] PRECURSEURS DE PARFUM
  申请人：PROCTER & GAMBLE

  公开号：WO2000063339A1

  公开（公告）日：2000-10-26

  The present invention relates to fragrance delivery systems which comprise: a) one or more pro-fragrances having formula (I) wherein G?1 and G2¿ are methyl, or a cyclic hydrocarbyl unit derived from the isomers of ionone and/or damascone; R and R1 are each independently C¿1?-C22 substituted or unsubstituted, branched or unbranched alkyl, C2-C22 substituted or unsubstituted, branched or unbranched alkenyl, C2-C20 substituted or unsubstituted, branched or unbranched hydroxyalkyl, C7-C20 substituted or unsubstituted alkylenearyl, C3-C20 substituted or unsubstituted cycloalkyl, alkyleneoxy; C6-C20 aryl, C5-C20 heteroaryl comprising one or more heteroatoms selected from the group consisting of nitrogen, oxygen, sulfur, and mixtures thereof; two of the units Y?1, Y2¿, R or R1 can be taken together to form one or more aromatic or non-aromatic, heterocyclic or non-heterocyclic, single rings, fused rings, bicyclo rings, spiroannulated rings, or mixtures thereof, said rings comprising from 3 to 20 carbon atoms and one or more heteroatoms selected from the group consisting of nitrogen, oxygen, sulfur, and mixtures thereof; b) one or more aldehyde releasing oxazolidine pro-fragrances; and c) the balance carriers, pro-fragrances, pro-accords, other perfume ingredients.