6,7-二氯-4-甲基-3-苯基-2H-苯并吡喃-2-酮 | 288399-87-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 中文名称: 6,7-二氯-4-甲基-3-苯基-2H-苯并吡喃-2-酮
• 英文名称: 6,7-Dichloro-4-methyl-3-phenylcoumarin
• 英文别名: 6,7-dichloro-4-methyl-3-phenylchromen-2-one
• CAS: 288399-87-1
• 化学式: C₁₆H₁₀Cl₂O₂
• 分子量: 305.2
• InChiKey: BPTRXIYZNCXNHE-UHFFFAOYSA-N

物化性质

• 沸点：
  466.4±45.0 °C(Predicted)
• 密度：
  1.379±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• POLYPEPTIDES AND THEIR USE
  申请人：Novabiotics Limited

  公开号：EP2825261A1

  公开（公告）日：2015-01-21
• USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY
  申请人：Stewart Colin

  公开号：US20100267653A1

  公开（公告）日：2010-10-21

  The invention provides coumarin compounds, in particular glycosidic coumarin compounds, useful in the treatment of dermatophyte fungal infections.
• Polypeptides and Their Use
  申请人：O'NEIL Deborah

  公开号：US20140155321A1

  公开（公告）日：2014-06-05

  The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.
• [EN] POLYPEPTIDES AND THEIR USE<br/>[FR] POLYPEPTIDES ET LEUR UTILISATION
  申请人：NOVABIOTICS LTD

  公开号：WO2013136040A1

  公开（公告）日：2013-09-19

  The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.