6,7-二氯-4-甲基-2-氧代-2H-苯并吡喃-3-甲腈 | 288399-86-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 中文名称: 6,7-二氯-4-甲基-2-氧代-2H-苯并吡喃-3-甲腈
• 英文名称: 3-Cyano-6,7-dichloro-4-methylcoumarin
• 英文别名: 6,7-dichloro-4-methyl-2-oxochromene-3-carbonitrile
• CAS: 288399-86-0
• 化学式: C₁₁H₅Cl₂NO₂
• 分子量: 254.07
• InChiKey: JLICVYDQXJPVPK-UHFFFAOYSA-N

物化性质

• 沸点：
  416.7±45.0 °C(Predicted)
• 密度：
  1.53±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• POLYPEPTIDES AND THEIR USE
  申请人：Novabiotics Limited

  公开号：EP2825261A1

  公开（公告）日：2015-01-21
• USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY
  申请人：Stewart Colin

  公开号：US20100267653A1

  公开（公告）日：2010-10-21

  The invention provides coumarin compounds, in particular glycosidic coumarin compounds, useful in the treatment of dermatophyte fungal infections.
• Polypeptides and Their Use
  申请人：O'NEIL Deborah

  公开号：US20140155321A1

  公开（公告）日：2014-06-05

  The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.
• [EN] POLYPEPTIDES AND THEIR USE<br/>[FR] POLYPEPTIDES ET LEUR UTILISATION
  申请人：NOVABIOTICS LTD

  公开号：WO2013136040A1

  公开（公告）日：2013-09-19

  The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.