苯并[b]吖啶 | 257-89-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 苯并[b]吖啶
• 英文名称: benz[b]acridine
• 英文别名: 2,3-Benzacridin；benzo[b]acridine；Benz(b)acridine
• CAS: 257-89-6
• 化学式: C₁₇H₁₁N
• 分子量: 229.281
• InChiKey: JZYMCIPZZLIJKR-UHFFFAOYSA-N

物化性质

• 保留指数：
  1720

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2933990090

反应信息

• 作为反应物：
  描述：

  苯并[b]吖啶 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 benzo[b]acridine-6,11-dione
  参考文献：
  名称：

  Etienne; Staehelin, Bulletin de la Societe Chimique de France, 1954, p. 748,751

  摘要：

  DOI：
• 作为产物：
  描述：

  2,3-二溴萘 在 甲醇 、 copper(l) iodide 、 lithium chloro-isopropyl-magnesium chloride 、 ammonium cerium (IV) nitrate 、 氢碘酸 、 sodium methylate 、 potassium carbonate 、 溶剂黄146 、 N,N'-二甲基乙二胺 作用下， 以 四氢呋喃 、 丙酮 、 甲苯 为溶剂， 反应 23.5h， 生成 苯并[b]吖啶
  参考文献：
  名称：

  铜催化酰胺的N，N-二芳基化反应用于构建9,10-二氢ac啶结构及其在合成氮包埋的聚乙炔中的应用。

  摘要：

  我们在本文中报道了CuI / DMEDA催化酰胺与各种二（邻-溴芳基）甲烷的N，N-二芳基化反应，以产生各种9,10-二氢ac啶衍生物。在温和条件下选择性氧化所得的9,10-二氢ac啶衍生物，得到afford啶，a啶酮和a啶鎓衍生物。铜催化的N，N-二芳基化反应与氧化芳构化反应相结合，使得能够容易地构建具有不同邻位熔融模式的氮原子嵌入的四碳烯和并五碳烯。还证明了发光特性，特别是融合模式对获得的N-多态荧光发射的影响。

  DOI：

  10.1021/acs.orglett.0c01775

文献信息

• ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER
  申请人：INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY

  公开号：US20190031586A1

  公开（公告）日：2019-01-31

  An organic compound, a three-dimensional organic structure formed by using the organic compound, a separation sieve and an optical layer having the organic structure, and an optical device having the optical layer as an optical amplification layer are provided. The organic structure includes a plurality of organic molecules self-assembled by non-covalent bonding. Each of the unit organic molecules has an aromatic ring, a first pair of substituents being connected to immediately adjacent positions of substitutable positions of the aromatic ring, and a second pair of substituents being connected to immediately adjacent positions of remaining substitutable positions of the aromatic ring. The unit organic molecules are self-assembled by van der Waals interaction, London dispersion interaction or hydrogen bonding between the first and the second pairs of the substituents and by pi-pi interactions between the aromatic rings.

  提供一种有机化合物，通过使用该有机化合物形成的三维有机结构、分离筛和具有该有机结构的光学层，以及具有光学层作为光学放大层的光学器件。该有机结构包括通过非共价键自组装的多个有机分子。每个单元有机分子具有芳香环，第一对取代基连接到芳香环的可取代位置的相邻位置，第二对取代基连接到芳香环的剩余可取代位置的相邻位置。单元有机分子通过范德华力相互作用、伦敦分散相互作用或氢键作用于第一和第二对取代基之间的π-π相互作用而自组装。
• Synthesis and characterization of oxadisilole-fused acridines, dioxatrisilole-fused acridines and benzo[b]acridines
  作者：Jie Zhang、Yali Chen、Xuanming Chen、Xiaoxing Zheng、Weiguo Cao、Jie Chen、Min Zhang

  DOI：10.1016/j.tet.2014.06.031

  日期：2014.9

  Oxadisilole-fused acridines, dioxatrisilole-fused acridines and benzo[b]acridines were synthesized through nucleophilic additions and aromatization reactions of arynes with 2-aminoaryl ketones or 2-aminoaryl aldehydes in good yields at room temperature. The photophysical, redox and thermal properties of these compounds were characterized. These compounds show potential applications as strong deep-blue

  通过芳烃与2-氨基芳基酮或2-氨基芳基醛的亲核加成和芳构化反应，在室温下以高收率合成了草二甲氧基-杂的a啶，二恶三三唑-sil杂的and啶和苯并[ b ] ac啶。表征了这些化合物的光物理性质，氧化还原性质和热性质。由于高的荧光量子产率和良好的热稳定性，这些化合物显示出潜在的应用作为OLED的深蓝色或绿色强发光体。
• Assays utilizing improved chemiluminescent esters, thioesters and amides
  申请人：LONDON DIAGNOSTICS, INC.

  公开号：EP0322926A2

  公开（公告）日：1989-07-05

  In accordance with the present invention, specific binding assays are disclosed which utilize an chemiluminescent compound, i.e., moiety, which has increased stability in aqueous solution. The chemiluminescent moiety is an ester, thioester or amide in which the ester, thioester or amide linkage is between (1) a heterocyclic ring or ring system containing a carbon atom to which the linkage is attached, wherein the heteroatom within the heterocyclic ring or ring system is in an oxidation state which renders such carbon atom susceptible to attack by peroxide or molecular oxygen to form an intermediate which decays to produce chemiluminescence, and (2) an aryl ring or ring system. The aryl ring or ring system contains at least one substituted six-member ring. The substituted six-member ring has two or more substituent groups, where at least two of said two or more substituent groups sterically hinder hydrolysis of said linkage. One or more of the substituent groups which sterically hinder hydrolysis of said linkage may be an electron withdrawing group. The substituted six-member ring may have one or more additional substituent groups in addition to the substituent groups which sterically hinder hydrolysis of the linkage. Such additional substituent groups may also be an electron withdrawing group. The carbon atoms in the heterocyclic ring or ring system, to which the linkage is attached, may also have a secondary substituent of the formula RnX-, where X is selected from the group consisting of O, N, S and C, where R is any group, and where n is a number such that X has proper valency. Other chemiluminescent moieties are disclosed which are characterized by a heterocyclic ring or ring system and a secondary substituent of the formula RnX-, with the ester, thioester or amide linkage being between the heterocyclic ring or ring system and a leaving group. The disclosed chemiluminescent moieties can also include substituents at peri positions within the heterocyclic ring or ring system. Also in accordance with the present invention, compositions including and assay kits incorporating such chemiluminescent moieties are disclosed.

  根据本发明，公开了利用化学发光化合物（即在水溶液中稳定性更强的分子）进行特异性结合测定的方法。化学发光分子是酯类、硫酯类或酰胺类，其中酯类、硫酯类或酰胺类连接在 (1) 杂环或环系之间，杂环或环系含有一个碳原子，连接在该碳原子上，杂环或环系中的杂原子处于氧化状态，使该碳原子易受过氧化物或分子氧的侵蚀而形成中间体，中间体衰变产生化学发光；(2) 芳环或环系。芳基环或环系统包含至少一个取代的六元环。取代的六元环具有两个或两个以上的取代基，其中至少有两个取代基在立体上阻碍了所述连接的水解。其中一个或多个取代基团可以是取电子基团，这些取代基团立体地阻碍了所述连接的水解。取代的六元环除了具有立体阻碍水解连接的取代基团外，还可以具有一个或多个额外的取代基团。这些额外的取代基团也可以是取电子基团。 连接该连接体的杂环或环系中的碳原子也可以具有式 RnX- 的仲取代基，其中 X 选自 O、N、S 和 C 组成的组，R 为任意基团，n 为使 X 具有适当价数的数字。还公开了其他化学发光分子，其特征在于杂环或环系和式 RnX- 的仲取代基，酯、硫酯或酰胺连接在杂环或环系和离去基团之间。所公开的化学发光分子还可以包括杂环或环系周围位置的取代基。 根据本发明，还公开了包含此类化学发光分子的组合物和检测试剂盒。
• Condensed quinoline system compound, condensed acridine system compound, process for preparing the same, and carcinostatic composition containing the same
  申请人：MECT CORPORATION

  公开号：EP0332190A2

  公开（公告）日：1989-09-13

  An indoloquinoline system compound represented by the following formula (1): A benzo(b)acridine system compound represented by the following formula (2): A benzo(c)acridine system compound represented by the following formula (3): Processes for preparing the above compounds and carcinostatic composition containing at least one of the above compounds.

  由下式（1）代表的吲哚喹啉系化合物： 由下式（2）代表的苯并(b)吖啶系化合物： 由下式（3）代表的苯并(c)吖啶系化合物： 制备上述化合物和含有至少一种上述化合物的致癌组合物的工艺。
• Long emission wavelength chemiluminescent compounds and their use in test assays
  申请人：CIBA-GEIGY AG

  公开号：EP0617288A2

  公开（公告）日：1994-09-28

  An assay method incorporating at least two different chemiluminescent compounds for detection and/or quantitation of at least two substances in a test sample is described. The synthesis of chemiluminescent reagents or conjugates for use in such methods as well as kits incorporating such reagents are also disclosed. The assays have particular application in the field of clinical diagnostics.

  描述了一种包含至少两种不同化学发光化合物的检测方法，用于检测和/或定量检测样品中的至少两种物质。此外，还公开了用于此类方法的化学发光试剂或共轭物的合成方法以及包含此类试剂的试剂盒。这些检测方法尤其适用于临床诊断领域。