2-Methoxy-benzo[a]xanthen-12-one | 76361-70-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 2-Methoxy-benzo[a]xanthen-12-one
• 英文别名: 2-Methoxybenzo[a]xanthen-12-one
• CAS: 76361-70-1
• 化学式: C₁₈H₁₂O₃
• 分子量: 276.291
• InChiKey: LWRNASVHODFRHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-Methoxy-benzo[a]xanthen-12-one 在 tetraphosphorus decasulfide 作用下， 以 甲苯 为溶剂， 以67%的产率得到2-Methoxybenzo[a]xanthene-12-thione
  参考文献：
  名称：

  4,5-Diazafluorene-Based Overcrowded Alkene:  A New Ligand for Transition Metal Complexes

  摘要：

  [GRAPHICS]A new ligand system, where a 4,5-diazafluorene-type chelate and a methoxybenzoxanthene unit are coupled by a double bond has been synthesized and fully characterized including X-ray structure. The synthesis and UV-vis spectra of Ru(II), Os(II), and Re(I) complexes with the above-mentioned ligand are also shown.

  DOI：

  10.1021/ol017130c
• 作为产物：
  描述：

  7-甲氧基-2-萘 在 tetrakis(actonitrile)copper(I) hexafluorophosphate 五氯化磷 、 四氯化锡 、 caesium carbonate 作用下， 以 甲苯 、 苯 为溶剂， 反应 38.0h， 生成 2-Methoxy-benzo[a]xanthen-12-one
  参考文献：
  名称：

  4,5-Diazafluorene-Based Overcrowded Alkene:  A New Ligand for Transition Metal Complexes

  摘要：

  [GRAPHICS]A new ligand system, where a 4,5-diazafluorene-type chelate and a methoxybenzoxanthene unit are coupled by a double bond has been synthesized and fully characterized including X-ray structure. The synthesis and UV-vis spectra of Ru(II), Os(II), and Re(I) complexes with the above-mentioned ligand are also shown.

  DOI：

  10.1021/ol017130c

文献信息

• Kumar, K. Akshaya; Srimannarayana, G., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1980, vol. 19, # 7, p. 615 - 616
  作者：Kumar, K. Akshaya、Srimannarayana, G.

  DOI：——

  日期：——
• KUMAR K. A.; SRIMANNARAYANA G., INDIAN J. CHEM., 1980, B19, NO 7, 615-616
  作者：KUMAR K. A.、 SRIMANNARAYANA G.

  DOI：——

  日期：——
• 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME
  申请人：Beeley Nigel Robert Arnold

  公开号：US20180185325A1

  公开（公告）日：2018-07-05

  The present invention provides compounds of the following structure, methods of using such compounds, and pharmaceutical compositions containing such compounds. In addition, this invention provides methods for the treatment and/or prevention of disease states mediated by Aryl Hydrocarbon receptor pathways.