2,4-二氯-3-乙基-6-[Α(2,4-二特戊基苯氧基)异丁酰氨基]苯酚 | 93951-12-3

• 物质功能分类: 有机原料 - 氨基化合物 - 酰胺类化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,4-二氯-3-乙基-6-[Α(2,4-二特戊基苯氧基)异丁酰氨基]苯酚
• 中文别名: 2,4-二氯-3-乙基-6-[α(2,4-二特戊基苯氧基)异丁酰氨基]苯酚；2-[α-(2,4-二特戊基苯氧基)丁酰胺基]-4,6-二氯-5-乙基苯酚；2-[2,4-双(1,1-二甲基丙基)苯氧基]-N-(3,5-二氯-4-乙基-2-羟基苯基)丁酰胺；YQ-6(乙基青),2-[2,4-双(1,1-二甲基丙基)苯氧基]-N-(3,5-二氯-4-乙基-2；2-[2,4-双(1,1-二甲基丙基)苯氧基]-3',5'-二氯-4'-乙基-2'-羟基丁酰苯胺
• 英文名称: 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]-N-[(3,5-dichloro-4-ethyl-2-hydroxyphenyl)] butanamide
• 英文别名: 2-(2,4-di-t-amylphenoxy)-N-(3,5-dichloro-4-ethyl-2-hydroxyphenyl)butyramide；2-(2,4-Bis(tert-pentyl)phenoxy)-N-(3,5-dichloro-4-ethyl-2-hydroxyphenyl)butyramide；2-[2,4-bis(2-methylbutan-2-yl)phenoxy]-N-(3,5-dichloro-4-ethyl-2-hydroxyphenyl)butanamide
• CAS: 93951-12-3
• 化学式: C₂₈H₃₉Cl₂NO₃
• 分子量: 508.529
• InChiKey: LFDFDMAPABBGSE-UHFFFAOYSA-N

物化性质

• 沸点：
  597.0±50.0 °C(Predicted)
• 密度：
  1.140±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.8
• 重原子数：
  34
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  6-氨基-2,4-二氯-3-乙基苯酚 在 2-[2,4-双(1,1-二甲基丙基)苯氧基]丁酰氯 、 potassium hydrogencarbonate 作用下， 以 正庚烷 、 水 、 异丙醇 、 甲苯 为溶剂， 反应 6.75h， 以92%的产率得到2,4-二氯-3-乙基-6-[Α(2,4-二特戊基苯氧基)异丁酰氨基]苯酚
  参考文献：
  名称：

  Continuous preparation of incorporated photographic amides

  摘要：

  本发明涉及一种制备包含照相酰胺的方法，包括：a) 连续混合能够形成包含照相酰胺的胺、酸氯化物、一种或多种吸酸试剂和一种或多种不与水相溶的溶剂，以连续形成反应混合物；b) 连续反应胺和酸氯化物以形成包含照相酰胺；以及c) 从反应混合物中分离出包含照相酰胺。

  公开号：

  EP1260499A3

文献信息

• Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith
  申请人：——

  公开号：US20030004235A1

  公开（公告）日：2003-01-02

  2H-Benzotriazole UV absorbers substituted at the 3-position and/or the 5-position of the phenyl ring by a phenyl moiety which is substituted by a heteroatom are particularly photostable in automotive coatings, and are of low color and exhibit low volatility in thermoplastic compositions.

  3-位和/或5-位被苯基环上的苯基取代的2H-苯并三唑紫外线吸收剂，其被异原子取代的苯基特别在汽车涂料中具有光稳定性，并且在热塑性复合材料中具有低色度和低挥发性。
• Process for producing aromatic amide compounds
  申请人：Sumitomo Chemical Company, Limited

  公开号：US05442114A1

  公开（公告）日：1995-08-15

  There is disclosed a process for producing an aromatic amide compound of the general formula (4), including the steps of subjecting an o-nitrophenol compound of the general formula (1) to catalytic reduction in acetone or an aromatic hydrocarbon solvent under the presence of a nickel catalyst to give an o-aminophenol compound of the general formula (2); and (b) subjecting the o-aminophenol compound of the general formula (2) to condensation with an acid chloride compound having a sulfur content of 0.5% or less, based on the weight of the acid chloride compound, of the general formula (3) in acetone or an aromatic hydrocarbon solvent under an atmosphere of an inert gas having an oxygen concentration of 1% or less. The acid chloride compound having a sulfur content of 0.5% or less, based on the weight of the acid chloride compound, of the general formula (3) may be obtained by allowing a carboxylic acid compound of the general formula (5) to react with thionyl chloride and by concentrating the reaction mixture. Also disclosed is another process for producing an aromatic amide compound of the general formula (4), including the step of subjecting an o-aminophenol hydrochloride salt of the general formula (6) to condensation with an acid chloride compound having a sulfur content of 0.8% or less, based on the weight of the acid chloride compound, of the general formula (3) in an inert solvent.

  本发明公开了一种生产通式（4）的芳香酰胺化合物的方法，包括以下步骤：将通式（1）的邻硝基酚化合物在丙酮或芳香烃溶剂中，在存在镍催化剂的条件下进行催化还原，得到通式（2）的邻氨基酚化合物；以及（b）将通式（2）的邻氨基酚化合物与含有硫含量不超过0.5%的酸氯化合物的通式（3）在丙酮或芳香烃溶剂中，在氧气浓度不超过1%的惰性气体氛围下，进行缩合反应。含有硫含量不超过0.5%的酸氯化合物的通式（3）可通过让通式（5）的羧酸化合物与亚砜氯反应，并浓缩反应混合物来获得。还公开了另一种生产通式（4）的芳香酰胺化合物的方法，包括以下步骤：将通式（6）的邻氨基酚盐酸盐与含有硫含量不超过0.8%的酸氯化合物的通式（3）在惰性溶剂中进行缩合反应。
• 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith
  申请人：——

  公开号：US20020169239A1

  公开（公告）日：2002-11-14

  2H-Benzotriazole UV absorbers substituted at the 3-position or at the 5-position of the phenyl ring by a 1,1-diphenylalkyl moiety, particularly a 1,1-diphenylethyl group, are particularly photostable in automotive coatings, and are of low color and exhibit low volatility in thermoplastic compositions.

  在汽车涂料中，3-位置或5-位置的苯环上被1,1-二苯基烷基基团（特别是1,1-二苯乙基基团）取代的2H-苯并三唑紫外线吸收剂，具有特别的光稳定性，并且在热塑性组合物中具有低色度和低挥发性。
• CONTINUOUS PREPARATION OF INCORPORATED PHOTOGRAPHIC AMIDES
  申请人：——

  公开号：US20020177731A1

  公开（公告）日：2002-11-28

  This invention relates to a method of making an incorporated photographic amide comprising a) continuously combining an amine capable of forming an incorporated photographic amide, an acid chloride, one or more acid-absorbing reagents, and one or more water-immiscible solvents to continuously form a reaction mixture; b) continuously reacting the amine and acid chloride to form an incorporated photographic amide; and c) separating the incorporated photographic amide from the reaction mixture.

  本发明涉及一种制备内含光敏酰胺的方法，包括：a）连续混合能够形成内含光敏酰胺的胺、酸氯化物、一个或多个吸酸试剂和一个或多个不与水相溶的溶剂，以连续形成反应混合物；b）连续反应胺和酸氯化物以形成内含光敏酰胺；c）从反应混合物中分离出内含光敏酰胺。
• Naphthyltriazines as stabilizers for organic material
  申请人：Toan Van Vien

  公开号：US20050169859A1

  公开（公告）日：2005-08-04

  Novel compounds of formula I are described wherein E corresponds to the formula or to the formula and the radicals R 1 , R 2 , R 11 , R 22 , R′ 22 , R′ 33 and R′33 are as defined in claim 1. Compounds of formula I are suitable for stabilising organic material, especially plastics materials, surface-coatings, cosmetic preparations, sun protection agents or photographic material, against damage by light, oxygen and/or heat.

  本发明涉及一种式I的新化合物，其中E代表式或代表式，而基团R1、R2、R11、R22、R′22、R′33和R′33如权利要求1所定义。式I的化合物适用于稳定有机材料，特别是塑料材料、表面涂层、化妆品制剂、防晒剂或照相材料，以防止光、氧和/或热损害。