28-Nor-olean-17-en-3-on | 5912-72-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 28-Nor-olean-17-en-3-on
• 英文别名: 28-Nor-Δ¹⁷-Oleanenon-3；28-Norolean-18(17)-en-3-on；28-nor-olean-17-en-3-one；28-Nor-oleanen-(17)-on-(3)；(4aR,6aR,6aR,6bR,14aR,14bR)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,4a,5,6,6a,7,8,9,10,12,13,14,14a-tetradecahydropicen-3-one
• CAS: 5912-72-1
• 化学式: C₂₉H₄₆O
• 分子量: 410.684
• InChiKey: YHNHHRQJUIOAOJ-RXVAIDOXSA-N

物化性质

• 熔点：
  176-178 °C
• 沸点：
  485.0±44.0 °C(Predicted)
• 密度：
  1.01±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  30
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  28-Nor-olean-17-en-3-on 在 盐酸 、 单过氧邻苯二甲酸 、 乙醚 、 二氯甲烷 、 氯仿 作用下， 生成 28-nor olean-12,17-dien-3-one
  参考文献：
  名称：

  Barton et al., Journal of the Chemical Society, 1957, p. 929,934

  摘要：

  DOI：
• 作为产物：
  描述：

  28-norolean-17-en-3β-ol 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 28-Nor-olean-17-en-3-on
  参考文献：
  名称：

  Winterstein; Stein, Justus Liebigs Annalen der Chemie, 1933, vol. 502, p. 223,234

  摘要：

  DOI：

文献信息

• Focus group composition: a comparison between natural and constructed groups
  作者：Julie Leask、Penelope Hawe、Simon Chapman

  DOI：10.1111/j.1753-6405.2001.tb01838.x

  日期：2001.4

  Objective: To provide insight into the effects of focus group composition.Method: In an early phase of an ongoing study of parental reception to messages about childhood immunisation, we conducted four focus groups; two with participants who had never met before (constructed groups) and two with participants who were part of a preestablished first-time mothers' group (natural groups).Results: Marked differences were noted in the group dynamics, depth of interaction and diversity between groups. Discussions with constructed groups were animated, enthusiastic, expressed more divergent views and articulated greater complexities of the topic. Discussions with natural groups were generally flatter and less enthusiastic, displaying a higher level of apparent conformity to conventional wisdom. The need to protect other participants from potentially disturbing information about vaccination was expressed across groups but acted to censor natural groups, where participants knew more of each others' sensitivities.Implications: Insight into the factors contributing to such differences may enhance understanding of the contexts in which constructed groups are more appropriate. The processes of social censorship may be of primary interest to the researcher. However, where it is paramount to elicit a range of opinions about a potentially controversial topic, we suggest that natural groups in the delicate stage of norming be avoided. The peculiarities of each individual research circumstance are best explored in pilot studies.
• Winterstein; Haemmerle, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1931, vol. 199, p. 56,62
  作者：Winterstein、Haemmerle

  DOI：——

  日期：——
• 271. Sapogenins. Part X. The carbon skeleton and the position of the second hydroxyl group of quillaic acid
  作者：Philip Bilham、George A. R. Kon

  DOI：10.1039/jr9400001469

  日期：——
• Chemistry of Aegiceras majus Gaertn. IIb. Isolation of 28-Norolean-12,17-dien-3β-ol
  作者：K. Venkateswara Rao、P. K. Bose

  DOI：10.1021/jo01051a525

  日期：1962.4