Dimethyl 2-but-3-ynyl-4-prop-1-en-2-ylcyclopent-3-ene-1,1-dicarboxylate | 944579-35-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Dimethyl 2-but-3-ynyl-4-prop-1-en-2-ylcyclopent-3-ene-1,1-dicarboxylate
• 英文别名: dimethyl 2-but-3-ynyl-4-prop-1-en-2-ylcyclopent-3-ene-1,1-dicarboxylate
• CAS: 944579-35-5
• 化学式: C₁₆H₂₀O₄
• 分子量: 276.332
• InChiKey: JYQXVQVLGSEHGO-UHFFFAOYSA-N

物化性质

• 沸点：
  335.3±32.0 °C(predicted)
• 密度：
  1.089±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Dimethyl 2-but-3-ynyl-4-prop-1-en-2-ylcyclopent-3-ene-1,1-dicarboxylate 在 palladium dichloride sodium acetate 、 copper dichloride 作用下， 以 乙腈 为溶剂， 生成 trimethyl (4R,11S)-10-methyltricyclo[5.3.1.04,11]undeca-1(10),7-diene-3,3,8-tricarboxylate
  参考文献：
  名称：

  An enyne metathesis/Diels–Alder reaction sequence towards the synthesis of cup-shaped 5/5/6-tricyclic architectures

  摘要：

  A strategy to synthesize the 5/5/6-tricyclic framework of presilphiperfolane natural products is described, involving a model dienyne compound (1). The key steps are an enyne metathesis reaction to introduce the diene part and a Diels-Alder cycloaddition to reveal the tricyclic architecture. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.04.107
• 作为产物：
  描述：

  在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 生成 Dimethyl 2-but-3-ynyl-4-prop-1-en-2-ylcyclopent-3-ene-1,1-dicarboxylate
  参考文献：
  名称：

  An enyne metathesis/Diels–Alder reaction sequence towards the synthesis of cup-shaped 5/5/6-tricyclic architectures

  摘要：

  A strategy to synthesize the 5/5/6-tricyclic framework of presilphiperfolane natural products is described, involving a model dienyne compound (1). The key steps are an enyne metathesis reaction to introduce the diene part and a Diels-Alder cycloaddition to reveal the tricyclic architecture. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.04.107

文献信息

• An enyne metathesis/Diels–Alder reaction sequence towards the synthesis of cup-shaped 5/5/6-tricyclic architectures
  作者：Laurent Evanno、Alexandre Deville、Bernard Bodo、Bastien Nay

  DOI：10.1016/j.tetlet.2007.04.107

  日期：2007.6

  A strategy to synthesize the 5/5/6-tricyclic framework of presilphiperfolane natural products is described, involving a model dienyne compound (1). The key steps are an enyne metathesis reaction to introduce the diene part and a Diels-Alder cycloaddition to reveal the tricyclic architecture. (c) 2007 Elsevier Ltd. All rights reserved.