ursa-9(11),12-dien-3-ol | 41753-44-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: ursa-9(11),12-dien-3-ol
• 英文别名: (3S,4aR,6aS,6bR,8aR,11R,12S,12aR,14bS)-4,4,6a,6b,8a,11,12,14b-octamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a-dodecahydro-1H-picen-3-ol
• CAS: 41753-44-0
• 化学式: C₃₀H₄₈O
• 分子量: 424.711
• InChiKey: CPSHPTCUXNWYJT-JHYJMQNKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  31
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  ursa-9(11),12-dien-3-ol 在 phosphorus pentoxide 、 苯 作用下， 生成 3ξH-A:B-neo-ursa-9,11,13(18)-triene
  参考文献：
  名称：

  15.三萜烯树脂醇和相关酸。第十五部分。α-香豆素和α-戊烯醇与氧化磷的脱水作用：l-α-戊二烯和l-α-戊三烯

  摘要：

  DOI：

  10.1039/jr9440000028
• 作为产物：
  描述：

  α-香树精 在 sulfur 作用下， 生成 ursa-9(11),12-dien-3-ol
  参考文献：
  名称：

  Jacobs; Fleck, Journal of Biological Chemistry, 1930, vol. 88, p. 137,151

  摘要：

  DOI：

文献信息

• Triterpenoids from Euphorbia maculata
  作者：Shunyo Matsunaga、Reiko Tanaka、Masao Akagi

  DOI：10.1016/0031-9422(88)83136-4

  日期：1988.1

  Abstract Two new triterpenoids were isolated together with β-amyrin acetate, taraxeryl acetate, lupenyl acetate, 3β-acetoxy-30-norlupan-20-one, α-amyrenonol and sitosterol from the whole herb of Euphorbia maculata. The structures of the new compounds were characterized as gult-5-en-3β-yl acetate and ursa-9(11):12-dien-3β-ol on the basis of chemical and spectral evidence.

  摘要 从斑大戟全草中分离得到两种新的三萜类化合物，分别为醋酸β-香树脂醇、醋酸蒲公英酯、醋酸羽扇豆酯、3β-乙酰氧基-30-norlupan-20-one、α-香树脂醇和谷甾醇。根据化学和光谱证据，新化合物的结构被表征为 gult-5-en-3β-yl acetate 和 ursa-9(11​​):12-dien-3β-ol。
• Zur Kenntnis der Triterpene. (78. Mitteilung). Einf�hrung zus�tzlicher Doppelbindungen beim ?- und ?-Amyrin-Typus mit N-Brom-succinimid
  作者：L. Ruzicka、O. Jeger、J. Redel

  DOI：10.1002/hlca.19430260426

  日期：1943.6.15
• 45. The resinols. Part IV. The structure of α-amyrenol
  作者：F. S. Spring、T. Vickerstaff

  DOI：10.1039/jr9370000249

  日期：——
• Epidural anesthesia in three parturients with lumbar tattoos: a review of possible implications
  作者：M. Joanne Douglas、Jean E. Swenerton

  DOI：10.1007/bf03017902

  日期：2002.12

  Purpose: To discuss the possible ramifications of neuraxial analgesia and anesthesia in women with tattoos involving their midline lumbar area.Clinical findings: Recently the authors have received requests for epidural anesthesia in three women with tattoos over the midline of their lumbar spine. In one patient the tattoo covered her entire back. In the other two, it was possible to locate a lumbar interspace that did not have tattoo pigment in the overlying skin. All three women received uneventful epidural analgesia.A Medline and EMBASE search for relevant publications using the keywords: epidural, spinal, tattoos, tattooing, complications did not find any reports of complications from inserting a needle through a tattoo. As none were found, the literature on tattoos and on coring with neuraxial anesthesia was reviewed to see if neuraxial anesthesia might be problematic if the needle passed through the tattoo. Coring is a complication of neuraxial anesthesia that may lead to epidermoid tumours in the subarachnoid space. Theoretically, a pigment-containing tissue, core from a tattoo could be deposited into the epidural, subdural or subarachnoid spaces, leading to later neurological complications.Conclusions: There is no information in the literature about possible risks from inserting needles through tattoos during the performance of neuraxial anesthesia. This report discusses the possible implications.
• Bhaumik, Tapanjyoti; Dey, A. K.; Das, P. C., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1981, vol. 20, # 8, p. 664 - 668
  作者：Bhaumik, Tapanjyoti、Dey, A. K.、Das, P. C.、Mukhopadhyay, A. K.、Chatterjee, A.

  DOI：——

  日期：——