2-(3-ethoxycarbonyl-1-ethyl-4-oxo-1,4-dihydroquinolin-6-yl)-5,10,15,20-tetraphenylporphyrinatozinc(II) | 1334214-69-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-(3-ethoxycarbonyl-1-ethyl-4-oxo-1,4-dihydroquinolin-6-yl)-5,10,15,20-tetraphenylporphyrinatozinc(II)
• CAS: 1334214-69-5
• 化学式: C₅₈H₄₁N₅O₃Zn
• 分子量: 921.385
• InChiKey: ARKJAXKQQVQRRD-TUDMZQQBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  2-(3-ethoxycarbonyl-1-ethyl-4-oxo-1,4-dihydroquinolin-6-yl)-5,10,15,20-tetraphenylporphyrinatozinc(II) 在 吡啶 、 三氟乙酸 、 potassium hydroxide 作用下， 以 四氢呋喃 、 甲醇 、 氯仿 为溶剂， 反应 1.03h， 生成 2-(3-carboxy-1-ethyl-4-oxo-1,4-dihydroquinolin-6-yl)-5,10,15,20-tetraphenylporphyrin
  参考文献：
  名称：

  Synthesis and characterization of new porphyrin/4-quinolone conjugates

  摘要：

  New porphyrin/4-quinolone conjugates were synthesized from the Suzuki-Miyaura coupling reaction of a beta-borylated porphyrin with bromo-4-quinolones containing N-ethyl and N-D-ribofuranosyl substituents. The use of electrospray ionization tandem mass spectrometry showed important information about the fragmentation pathways of the new compounds. It was possible to distinguish between those compounds with the porphyrin moiety linked at the 6-position of the quinolone unit from their 7-substituted isomers. The new compounds showed to be good singlet oxygen generators. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.07.025
• 作为产物：
  描述：

  2-bromo-5,10,15,20-tetraphenylporphyrinatozinc(II) 在 bis-triphenylphosphine-palladium(II) chloride 、 四(三苯基膦)钯 、 caesium carbonate 作用下， 以 1,2-二氯乙烷 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 34.0h， 生成 2-(3-ethoxycarbonyl-1-ethyl-4-oxo-1,4-dihydroquinolin-6-yl)-5,10,15,20-tetraphenylporphyrinatozinc(II)
  参考文献：
  名称：

  Synthesis and characterization of new porphyrin/4-quinolone conjugates

  摘要：

  New porphyrin/4-quinolone conjugates were synthesized from the Suzuki-Miyaura coupling reaction of a beta-borylated porphyrin with bromo-4-quinolones containing N-ethyl and N-D-ribofuranosyl substituents. The use of electrospray ionization tandem mass spectrometry showed important information about the fragmentation pathways of the new compounds. It was possible to distinguish between those compounds with the porphyrin moiety linked at the 6-position of the quinolone unit from their 7-substituted isomers. The new compounds showed to be good singlet oxygen generators. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.07.025