(Z)-1-(3,7-dimethylocta-2,6-dienyl)piperidine | 46742-23-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (Z)-1-(3,7-dimethylocta-2,6-dienyl)piperidine
• 英文别名: N-(3,7-dimethyl-2,6-octadienyl)piperidine；1-Nerylpiperidine；1-[(2Z)-3,7-dimethylocta-2,6-dienyl]piperidine
• CAS: 46742-23-8
• 化学式: C₁₅H₂₇N
• 分子量: 221.386
• InChiKey: DKUCHUIKIVUQEN-GDNBJRDFSA-N

物化性质

• 沸点：
  308.2±21.0 °C(Predicted)
• 密度：
  0.871±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-1-(3,7-dimethylocta-2,6-dienyl)piperidine 在 镍 氢气 作用下， 以 正庚烷 、 苯 为溶剂， 60.0 ℃ 、10.13 MPa 条件下， 反应 84.0h， 生成 1-(3,7-dimethyloctyl)-1-methylpiperidinium iodide
  参考文献：
  名称：

  Synthesis of New Plant Growth Regulators, Isomeric 1-(Dimethyloctyl)- and 1-Alkylpiperidinium and -morpholinium Halides by Telomerization of Isoprene with Secondary Amines

  摘要：

  The known plant growth regulator, Al'den [1-(3,7-dimethyloctyl)-1-allylpiperidinium bromide], and also 1-(3,7-dimethyloctyl)-1-methylpiperidinium iodide were synthesized by treatment with allyl bromide and methyl iodide, respectively, of exhaustively hydrogenated 1-nerylpiperidine which was obtained by anionic telomerization of isoprene with piperidine. Various quaternary ammonium salts having a terpene substituent with unnatural dimethyloctane skeleton, which effectively stimulate florification of Aster Chinensis L., were prepared by the action of alkyl halides on telomerization products derived from isoprene and piperidine or morpholine in the presence of palladium complexes.

  DOI：

  10.1023/b:rugc.0000016041.29564.e9
• 作为产物：
  描述：

  哌啶 、 天然橡胶 在 正丁基锂 作用下， 以 苯 为溶剂， 反应 7.0h， 以78%的产率得到(Z)-1-(3,7-dimethylocta-2,6-dienyl)piperidine
  参考文献：
  名称：

  Synthesis of New Plant Growth Regulators, Isomeric 1-(Dimethyloctyl)- and 1-Alkylpiperidinium and -morpholinium Halides by Telomerization of Isoprene with Secondary Amines

  摘要：

  The known plant growth regulator, Al'den [1-(3,7-dimethyloctyl)-1-allylpiperidinium bromide], and also 1-(3,7-dimethyloctyl)-1-methylpiperidinium iodide were synthesized by treatment with allyl bromide and methyl iodide, respectively, of exhaustively hydrogenated 1-nerylpiperidine which was obtained by anionic telomerization of isoprene with piperidine. Various quaternary ammonium salts having a terpene substituent with unnatural dimethyloctane skeleton, which effectively stimulate florification of Aster Chinensis L., were prepared by the action of alkyl halides on telomerization products derived from isoprene and piperidine or morpholine in the presence of palladium complexes.

  DOI：

  10.1023/b:rugc.0000016041.29564.e9

文献信息

• Heavier Alkaline Earth Catalysts for the Intermolecular Hydroamination of Vinylarenes, Dienes, and Alkynes
  作者：Christine Brinkmann、Anthony G. M. Barrett、Michael S. Hill、Panayiotis A. Procopiou

  DOI：10.1021/ja209135t

  日期：2012.2.1

  nucleophilicity. Hydroamination of conjugated dienes yielded isomeric products via η(3)-allyl intermediates and their relative distributions were explained through stereoelectronic considerations. The ability to carry out the hydroamination of internal alkynes was found to be dramatically dependent upon the identity of the alkyne substituents while reactions employing terminal alkynes resulted in the

  较重的第 2 族络合物 [MN(SiMe(3))(2)}(2)](2)(1, M = Ca; 2, M = Sr) 和 [MCH(SiMe(3)) (2)}(2)(THF)(2)] (3, M = Ca; 4, M = Sr) 被证明是温和条件下乙烯基芳烃和二烯分子间加氢胺化的有效预催化剂。初步研究表明，酰胺预催化剂 1 和 2 虽然在绝对活性方面受到氨基转移行为的影响，但对聚合/低聚副反应具有更高的稳定性。在每种情况下，锶物质 2 和 4 都被发现优于它们的钙同类物。哌啶与对位取代苯乙烯的反应表明催化循环中烯烃插入的速率决定性，而环仲胺的添加容易程度被发现取决于环的大小，并被认为是不同胺亲核性的结果。共轭二烯的加氢胺化通过 η(3)-烯丙基中间体产生异构产物，并通过立体电子考虑解释了它们的相对分布。发现进行内部炔烃的加氢胺化的能力极大地取决于炔烃取代基的身份，而使用末端炔烃的反应导致不溶性和非反应性第
• ZAXARKIN, L. I.;GUSEVA, V. V.;PETRUSHKINA, E. A.
  作者：ZAXARKIN, L. I.、GUSEVA, V. V.、PETRUSHKINA, E. A.

  DOI：——

  日期：——