Synthesis of allylic ketones via acylation of allylic mercurials
作者:Richard C. Larock、Yong-de Lu
DOI:10.1016/s0040-4039(00)82448-x
日期:——
Allylic mercurials, readily available from allylic halides and mercury(O), react with acyl chlorides and AlCl3 under mild reaction conditions to afford high yields of allylic ketones.
Concerning reversal of diastereoselectivity in the BF3 promoted addition of crotyl—organometallic compounds to aldehydes
作者:Yoshinori Yamamoto、Kazuhiro Maruyama
DOI:10.1016/0022-328x(85)80039-5
日期:1985.4
The addition of a mixture of benzaldehyde and BF3·OEt2 to crotyl-organometallic reagents C4H7MLn (1) (M = Cu, Cd, Hg, Tl, Ti, Zr and V) produces predominantly the erythro homoallyl alcohol as well as the α-adduct, while without BF3·OEt2 the threo isomer is formed preferentially.
Synthesis and acylation of allylic mercuric iodides: a convenient synthesis of allylic ketones
作者:Richard C. Larock、Yong De Lu
DOI:10.1021/jo00062a031
日期:1993.5
Allylic mercuric iodides are readily prepared by the reaction of mercury(0) and allylic iodides. They undergo efficient acylation with allylic rearrangement upon reaction with acyl chlorides and aluminum chloride to provide a convenient synthesis of allylic ketones. Artemisia ketone is prepared in two steps by this approach.