halocyanthiaxanthin | 81306-52-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: halocyanthiaxanthin
• 英文别名: Halocynthiaxanthin；Hx；(3E,5E,7E,9E,11E,13E,15E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-1-[(1S,4S,6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl]-3,7,12,16-tetramethyloctadeca-3,5,7,9,11,13,15-heptaen-17-yn-2-one
• CAS: 81306-52-7；123286-78-2
• 化学式: C₄₀H₅₄O₄
• 分子量: 598.866
• InChiKey: CNOIXMULOQWVGR-ABUIXNMTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  44
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  70.1
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  halocyanthiaxanthin 在 sodium tetrahydroborate 作用下， 生成 (1R,3S,6S)-6-[(3E,5E,7E,9E,11E,13E,15E)-2-Hydroxy-18-((R)-4-hydroxy-2,6,6-trimethyl-cyclohex-1-enyl)-3,7,12,16-tetramethyl-octadeca-3,5,7,9,11,13,15-heptaen-17-ynyl]-1,5,5-trimethyl-7-oxa-bicyclo[4.1.0]heptan-3-ol
  参考文献：
  名称：

  Matsuno, Takao; Ookubo, Masahiro; Nishizawa, Tokuji, Chemical and pharmaceutical bulletin, 1984, vol. 32, # 11, p. 4309 - 4315

  摘要：

  DOI：
• 作为产物：
  描述：

  (2E,4E,6E,8Z,10E)-13-(4-hydroxy-2,6,6-trimethylcyclohex-1-enyl)-2,7,11-trimethyl-12-oxotrideca-2,4,6,8,10-pentaenal 在 双(乙腈)氯化钯(II) 、 水 、 sodium methylate 、 三乙胺 、 间氯过氧苯甲酸 作用下， 以 甲醇 、 二氯甲烷 、 乙腈 为溶剂， 反应 3.75h， 生成 halocyanthiaxanthin
  参考文献：
  名称：

  Yamano, Yumiko; Tode, Chisato; Ito, Masayoshi, Journal of the Chemical Society. Perkin transactions I, 1995, # 15, p. 1895 - 1904

  摘要：

  DOI：

文献信息

• COMPOSITION, AND EXTERNAL PREPARATION FOR THE SKIN OR FUNCTIONAL FOOD EACH CONTAINING SAID COMPOSITION
  申请人：FUJI-FILM Corporation

  公开号：EP2832344A1

  公开（公告）日：2015-02-04

  The present invention provides a composition which has an effect of preventing or improving symptoms of skin such as fine wrinkles or sagging of skin, and an external preparation for skin or a functional food containing the composition. The present invention is a composition containing carotenoid and pterostilbene and an external preparation for skin or a functional food containing the composition.

  本发明提供了一种具有预防或改善细小皱纹或皮肤松弛等皮肤症状效果的组合物，以及含有该组合物的皮肤外用制剂或功能性食品。本发明是一种含有类胡萝卜素和紫檀芪的组合物，以及含有该组合物的皮肤外用制剂或功能性食品。
• COMPOSITION FOR EXTERNAL USE THAT INCLUDES PTEROSTILBENE GLYCOSIDE
  申请人：Tomoike Industrial (H.K.) Limited

  公开号：EP3501490A1

  公开（公告）日：2019-06-26

  The present invention addresses the problem of providing a composition for external use that is effective for preventing or reducing wrinkles or sagging of the skin, or a composition for external use that is effective for skin whitening, or both of these compositions. The problem is solved by providing a composition for external use containing a pterostilbene glycoside.

  本发明要解决的问题是提供一种外用组合物，它能有效防止或减少皮肤皱纹或松弛，或提供一种外用组合物，它能有效美白皮肤，或同时提供这两种组合物。本发明通过提供一种含有紫檀甙的外用组合物来解决这一问题。
• Compositions and methods for making and using nanoemulsions
  申请人：University of Massachusetts Lowell

  公开号：US10016364B2

  公开（公告）日：2018-07-10

  The present invention discloses an improved nanoemulsion comprising a uniform and discrete range of very small particle nano-sized diameters. This uniformity results in improved bioavailability of incorporated compounds (i.e., pharmaceuticals or nutraceuticals) as reflected in various pharmacokinetic parameters including, but not limited to, decreased Tmax, increased CmaX3 and increased AUC. The improved method of making these uniform nanoemulsions utilizes microfluidization which differs in both process and mechanics when compared to conventional milling and grinding techniques used to generate nanoparticulate compositions. Further, the improvement results, in part, from a novel step of mixing a substantially soluble compound into a heated dispersion medium. This is unlike current nanoparticulate composition methods that mix an insoluble compound with an unheated dispersion medium. Further, these nanoemulsions are observed to be bacterial-resistant and stable to extremes in both temperature and pH changes. Consequently, these nanoemulsions are expected to have a significantly prolonged shelf-life than currently available nanoemulsions.

  本发明公开了一种改进型纳米乳液，它包含均匀且离散的极小颗粒纳米尺寸直径范围。这种均匀性提高了掺入化合物（即药物或营养保健品）的生物利用度，反映在各种药代动力学参数上，包括但不限于Tmax降低、CmaX3升高和AUC升高。制造这些均匀纳米乳剂的改进方法利用了微流化技术，与用于生成纳米颗粒组合物的传统研磨和磨削技术相比，微流化技术在工艺和机械方面都有所不同。此外，改进的部分原因是采用了新颖的步骤，即把基本可溶的化合物混合到加热的分散介质中。这与目前将不溶性化合物与未加热的分散介质混合的纳米颗粒组合物方法不同。此外，据观察，这些纳米乳液具有抗细菌性，对极端温度和 pH 值变化都很稳定。因此，与目前可用的纳米乳剂相比，这些纳米乳剂的保质期有望大大延长。
• Methods for processing crustacean material
  申请人：——

  公开号：US20030185939A1

  公开（公告）日：2003-10-02

  The inventor has found that enzymatic treatment of crustaceans with lipolytic enzymes promotes the extraction of coloured pigment. Accordingly, the invention relates to a method for recovering coloured pigment, e.g. astaxanthin, and/or chitin or chitosan and/or lysolecithins from crustaceans. Lipolytic enzyme(s) may e.g. be lipase or phospholipase. The lipolytic enzyme treated crustacean material may be subjected to additional process steps, including treatment with non-lipolytic enzymes such as e.g. protease. The process of the invention provides several suitable products and several uses of such products. Furthermore, the invention also relates to the cosmetic and consumable products (feed and food (including beverages) products and additives produced therefrom.

  本发明者发现，用脂肪分解酶对甲壳类动物进行酶处理可促进有色色素的提取。因此，本发明涉及一种从甲壳类动物中回收有色色素（如虾青素）和/或甲壳素或壳聚糖和/或溶血卵磷脂的方法。脂肪分解酶可以是脂肪酶或磷脂酶等。经脂肪分解酶处理过的甲壳动物材料还可进行其他加工步骤，包括用非脂肪分解酶（如蛋白酶）处理。本发明的工艺提供了几种合适的产品和这些产品的几种用途。此外，本发明还涉及由此生产的化妆品和消费品（饲料和食品（包括饮料）产品和添加剂）。
• COMPOSITION FOR THE TREATMENT OF HIV OR AIDS
  申请人：VITABIOTICS LIMITED

  公开号：EP1590046A2

  公开（公告）日：2005-11-02