α-D-Man-(1->2)-α-D-Man-(1->2)-α-D-Man | 77447-85-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-D-Man-(1->2)-α-D-Man-(1->2)-α-D-Man
• 英文别名: Man(a1-2)Man(a1-2)a-Man；(2S,3S,4S,5S,6R)-3-[(2R,3S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,4,5-triol
• CAS: 77447-85-9
• 化学式: C₁₈H₃₂O₁₆
• 分子量: 504.442
• InChiKey: UQBIAGWOJDEOMN-NAVBLJQLSA-N

物化性质

• 沸点：
  892.3±65.0 °C(Predicted)
• 密度：
  1.80±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -5.8
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  269
• 氢给体数：
  11
• 氢受体数：
  16

反应信息

• 作为产物：
  描述：

  2,3,4,6-四-O-乙酰基-1-溴-Alpha-D-甘露糖 在 palladium on activated charcoal 、 sodium methylate 4 A molecular sieve 、 氢气 、 sodium methylate 、 silver trifluoromethanesulfonate 、 sodium hydride 、 mercury dibromide 作用下， 以 四氢呋喃 、 甲醇 、 溶剂黄146 、 1,2-二氯乙烷 为溶剂， 反应 67.0h， 生成 α-D-Man-(1->2)-α-D-Man-(1->2)-α-D-Man
  参考文献：
  名称：

  Synthesis of linear d-mannotetraose and d-mannohexaose, partial structures of the cell-surface d-mannan of Candida albicans and Candida utilis

  摘要：

  DOI：

  10.1016/s0008-6215(00)82588-4

文献信息

• Synthesis and Semisynthesis of Some Structural Elements of Oligo-Mannose Type N-Glycoproteins
  作者：Zoltán Szurmai、Lóránt Jánossy、Zoltán Szilágyi、Károly Vékey

  DOI：10.1080/07328309808002903

  日期：1998.4

  For the construction of N-glycoprotein glycan chains, valuable potential glycosyl donors, O-alpha-D-mannopyranosyl-(1-->2)-alpha-D-mannopyranose octaacetate (19) and O-alpha-D-mannopyranosyl-(1-->2)-O-alpha-D-mannopyranosyl-(1-->2)-alpha-D-mannopyranose undecaacetate (20) were obtained in gram-scale by the acetylation and subsequent partial acetolysis of baker's yeast, without the isolation of mannan. The acetolytic products were investigated by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Octaacetates of mannobiose (1-->3) (11) and (1-->6) (17) were chemically synthesized.
• Synthesis of linear d-mannotetraose and d-mannohexaose, partial structures of the cell-surface d-mannan of Candida albicans and Candida utilis
  作者：Tomoya Ogawa、Hisao Yamamoto

  DOI：10.1016/s0008-6215(00)82588-4

  日期：1982.6