异蒽黄素 | 572-93-0

• 物质功能分类: 有机原料 - 烃类化合物及其衍生物 - 芳香烃
• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 异蒽黄素
• 中文别名: 二羟基二苯并环己酮
• 英文名称: 2,7-dihydroxy-anthraquinone
• 英文别名: 2,7-dihydroxy-9,10-anthraquinone；2,7-dihydroxy anthraquinone；2,7-Dihydroxyanthrachinon；2,7-Dihydroxy-anthrachinon；2,7-dihydroxy-9,10-anthracenedione；2,7-dihydroxyanthraquinone；2,7-Dihydroxyanthracene-9,10-dione
• CAS: 572-93-0
• 化学式: C₁₄H₈O₄
• 分子量: 240.215
• InChiKey: RZTIWMXQXBQJNE-UHFFFAOYSA-N

物化性质

• 熔点：
  >320 °C(lit.)
• 沸点：
  342.92°C (rough estimate)
• 密度：
  1.3032 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2914690090

反应信息

• 作为反应物：
  描述：

  异蒽黄素 在 乙醚 、 lithium 、 sodium carbonate 作用下， 生成 2,7-dimethoxy-9,10-diphenyl-9,10-dihydro-anthracene-9,10-diol
  参考文献：
  名称：

  Etienne; Lepely; Heymes, Bulletin de la Societe Chimique de France, 1949, p. 835,840

  摘要：

  DOI：
• 作为产物：
  描述：

  2,7-蒽醌二磺酸 生成 异蒽黄素
  参考文献：
  名称：

  Hall; Perkin, Journal of the Chemical Society, 1923, vol. 123, p. 2036

  摘要：

  DOI：

文献信息

• Bis-basic ethers of 2,6- and 2,7-dihydroxyanthraquinones
  申请人：Richardson-Merrell Inc.

  公开号：US03974186A1

  公开（公告）日：1976-08-10

  Disclosed are novel compounds and pharmaceutical formulations having antiviral activity. The disclosed compounds have the formula ##SPC1## Wherein one R.sup.2 is a hydrogen atom and the other R.sup.2 is the radical ##SPC2## A is a straight chain alkylene group having 2 or 3 carbon atoms and each R.sup.3 and R.sup.4 is a hydrogen atom, an alkyl radical having 1 to 3 carbon atoms or each set of R.sup.3 and R.sup.4 taken together with the nitrogen atom to which they are attached is a saturated monocyclic heterocyclic group. Also included are the acid addition salts of these bases. These compounds may be prepared by various methods which are described.

  本文披露了具有抗病毒活性的新化合物和制药配方。所披露的化合物具有以下结构式：其中一个R.sup.2是氢原子，另一个R.sup.2是基团A，A是具有2或3个碳原子的直链烷基基团，每个R.sup.3和R.sup.4是氢原子，具有1至3个碳原子的烷基基团，或者每组R.sup.3和R.sup.4与它们连接的氮原子一起形成饱和的单环杂环基团。还包括这些碱的酸盐。这些化合物可以通过描述的各种方法制备。
• Pharmaceutically useful nitrogen containing heterocyclic derivatives
  申请人：Richardson-Merrell Inc.

  公开号：US03937833A1

  公开（公告）日：1976-02-10

  Bis-basic substituted aromatic polycyclic compounds of the following structure are useful in treating conditions of delayed hypersensitivity: ##SPC1## Wherein [W] represents an aromatic polycyclic nucleus selected from fluoranthene, fluorene, fluoren-9-ol, fluoren-9-one, dibenzofuran, dibenzothiophene, carbazole, N-(lower)alkyl carbazole, xanthene, xanthone, thioxanthene, phenoxathiin, or anthraquinone; Y represents carbonyloxy, carbonylthio, oxygen, divalent sulfur or carbonyl with the provisos that when Y is carbonyloxy or carbonylthio, [W] is other than thioxanthene, phenoxathiin or anthraquinone, when Y is oxygen or divalent sulfur, [W] is other than thioxanthene or phenoxathiin, and when Y is carbonyl, [W] is other than fluoren-9-ol or anthraquinone; A represents a straight or branched alkylene chain of from 1 to 6 carbon atoms with the proviso that when Y is carbonyloxy or carbonylthio, A contains at least 2 straight chain carbon atoms, that is, an ethylene radical; R represents hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, phenyl or benzyl; and pharmaceutically useful acid addition salts.

  以下结构的Bis-基取代芳香族多环化合物在治疗延迟型超敏反应方面很有用：##SPC1## 其中[W]代表从荧蒽、芴、芴-9-醇、芴-9-酮、二苯并呋喃、二苯并噻吩、咔唑、N-(较低)烷基咔唑、苯酚氧噻吩或蒽醌中选的芳香族多环核；Y代表羰氧基、羰硫基、氧、二价硫或羰基，但当Y为羰氧基或羰硫基时，[W]不是噻吩、苯酚氧噻吩或蒽醌，当Y为氧或二价硫时，[W]不是噻吩或苯酚氧噻吩，当Y为羰基时，[W]不是芴-9-醇或蒽醌；A代表1至6个碳原子的直链或支链烷基链，但当Y为羰氧基或羰硫基时，A含有至少2个直链碳原子，即乙烯基；R代表氢、1至4个碳原子的直链或支链低级烷基、苯基或苄基；以及药用酸盐。
• Pharmaceutically useful bis-amine derivatives
  申请人：Richardson-Merrell Inc.

  公开号：US03947593A1

  公开（公告）日：1976-03-30

  Compounds of the following general structure are useful in treating conditions of delayed hypersensitivity: ##EQU1## wherein [W] represents an aromatic polycyclic nucleus selected from fluoranthene, fluorene, fluoren-9-ol, fluoren-9-one, carbazole, N-(lower) alkyl carbazole or anthraquinone; Y represents carbonyl, divalent sulfur or oxygen; with the proviso that when Y is carbonyl, [W] is other than fluoren-9-ol or anthraquinone; A represents a straight or branched alkylene chain of from 1 to 6 carbon atoms; and each of R.sup.1 and R.sup.2 represents hydrogen, lower alkyl of from 1 to 4 carbon atoms, or alkenyl of from 3 to 6 carbon atoms having the vinyl unsaturation in other than the 1-position; and pharmaceutically useful acid addition salts thereof.

  下列一般结构的化合物对于治疗延迟超敏反应的病症是有用的：##EQU1## 其中[W]代表从氟蒽、芴、芴-9-醇、芴-9-酮、咔唑、N-(较低)烷基咔唑或蒽醌中选取的芳香多环核；Y代表羰基、二价硫或氧；条件是当Y为羰基时，[W]不是芴-9-醇或蒽醌；A代表由1至6个碳原子组成的直链或支链烷基链；而且R1和R2中的每一个代表氢、由1至4个碳原子的低烷基或由3至6个碳原子且具有乙烯基不饱和度但不在1-位置上的烯基；以及其药学上有用的酸盐。
• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427A2

  公开（公告）日：1986-02-26

  This process is a process for production of a vinyl chloride polymer by suspension polymerization or emulsion polymerization of vinyl chloride monomer or a mixture of vinyl chloride monomer with a vinyl monomer copolymerizable with said vinyl chloride monomer in an aqueous medium, characterized in that the polymerization is carried out in a polymerizer, the inner wall surface and portions of the auxiliary equipment thereof which may come into contact with the monomer during polymerization being previously coated with a scaling preventive comprising at least one selected from dyes, pigments and aromatic or heterocyclic compounds having at least 5 conjugated π bonds, while controlling the chloride ion concentration in the reaction mixture to not higher than 100 ppm. According to said process, scaling onto the inner wall surface of a polymerizer, etc. during polymerization can be prevented effectively and surely.

  该工艺是通过氯乙烯单体或氯乙烯单体与可与所述氯乙烯单体共聚的乙烯基单体混合物在水介质中进行悬浮聚合或乳液聚合来生产氯乙烯聚合物的工艺，其特征在于聚合是在聚合器中进行的、内壁表面及其辅助设备中可能在聚合过程中与单体接触的部分事先涂上一层防垢剂，该防垢剂至少包括一种选自染料、颜料和至少有 5 个共轭 π 键的芳香族或杂环化合物的防垢剂，同时控制反应混合物中的氯离子浓度不高于 100 ppm。根据上述工艺，可有效、可靠地防止聚合过程中聚合器等内壁表面结垢。
• Method of preventing polymer-scale formation
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0320227A2

  公开（公告）日：1989-06-14

  A method of preventing polymer scales from sticking in a polymerization vessel during the polymerization of a monomer having an ethylenically double bond, wherein said polymerization is carried out in a polymerization vessel of which the inner wall and other parts with which said monomer comes into contact during polymerization are previously first coated with (a) a coating solution comprising a cationic dye and the resulting coating is then coated with (b) a coating solution comprising at least one component selected from the group consisting of anionic polymeric compounds, amphoteric polymeric compounds and hydroxyl group-containing organic compounds. Polymer scale formation can be effectively prevented.

  一种在具有乙烯双键的单体聚合过程中防止聚合物鳞片粘附在聚合容器中的方法，其中所述聚合在聚合容器中进行，聚合容器的内壁和在聚合过程中与所述单体接触的其他部分之前先涂有(a)由阳离子染料组成的涂层溶液，然后在所得涂层上涂有(b)由至少一种从阴离子聚合物化合物、两性聚合物化合物和含羟基有机化合物组成的组中选出的组分组成的涂层溶液。可有效防止聚合物结垢。