2-(2,2,4-Trimethyl-cyclopent-3-en-1-yl)propanal | 123822-43-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-(2,2,4-Trimethyl-cyclopent-3-en-1-yl)propanal
• 英文别名: 2-(2,2,4-Trimethylcyclopent-3-en-1-yl)propanal
• CAS: 123822-43-5
• 化学式: C₁₁H₁₈O
• 分子量: 166.263
• InChiKey: XVFXQGLNLQFBTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-(2,2,4-Trimethyl-cyclopent-3-en-1-yl)propanal 在 platinum(IV) oxide 甲醇 、 氢氧化钾 、 lithium aluminium tetrahydride 、 氢气 、 对甲苯磺酸 作用下， 以 甲醇 、 乙醚 、 二氯甲烷 为溶剂， 15.0~25.0 ℃ 、101.33 kPa 条件下， 反应 6.0h， 生成 5-(2,2,4-Trimethyl-cyclopent-3-enyl)-hexan-2-ol
  参考文献：
  名称：

  ?-Methylierter Fencholen- und ?-Campholenaldehyd - Synthese und Reaktionen

  摘要：

  The syntheses of alpha-methylated fencholenic (6a) and alpha-campholenic aldehyde (6b) via the corresponding azomethines (5) are reported. Aldol condensations of 6a, b with following reductions give the allylic alcohols (12-16) and hydrogenation the saturated alcohols (17-21) with strong woody odors, some of the allylic alcohols resembling that of sandal wood. Simple reduction or oxidation of 6a, b give the alcohols (24, 27), ethers (26), esters (23, 25, 28) and ketones (29) which have interesting woody odors with spicy, earthy and herbaceous notes.

  DOI：

  10.1002/prac.19933350807
• 作为产物：
  描述：

  Cyclohexyl-[2-(2,2,4-trimethyl-cyclopent-3-enyl)-eth-(E)-ylidene]-amine 、 碘甲烷 在 乙基溴化镁 作用下， 生成 2-(2,2,4-Trimethyl-cyclopent-3-en-1-yl)propanal
  参考文献：
  名称：

  ?-Methylierter Fencholen- und ?-Campholenaldehyd - Synthese und Reaktionen

  摘要：

  The syntheses of alpha-methylated fencholenic (6a) and alpha-campholenic aldehyde (6b) via the corresponding azomethines (5) are reported. Aldol condensations of 6a, b with following reductions give the allylic alcohols (12-16) and hydrogenation the saturated alcohols (17-21) with strong woody odors, some of the allylic alcohols resembling that of sandal wood. Simple reduction or oxidation of 6a, b give the alcohols (24, 27), ethers (26), esters (23, 25, 28) and ketones (29) which have interesting woody odors with spicy, earthy and herbaceous notes.

  DOI：

  10.1002/prac.19933350807

文献信息

• UHLIG, HOLGER;SCHULZE, KLAUS;ENGEWALD, WERNER;KOHLER, ERIKA
  作者：UHLIG, HOLGER、SCHULZE, KLAUS、ENGEWALD, WERNER、KOHLER, ERIKA

  DOI：——

  日期：——
• UHLIG, HOLGER;SCHULZE, KLAUS
  作者：UHLIG, HOLGER、SCHULZE, KLAUS

  DOI：——

  日期：——
• UHLIG, HOLGER;SCHULZE, KLAUS;TRAUER, HEINER
  作者：UHLIG, HOLGER、SCHULZE, KLAUS、TRAUER, HEINER

  DOI：——

  日期：——
• ?-Methylierter Fencholen- und ?-Campholenaldehyd - Synthese und Reaktionen
  作者：K. Schulze、A.-K. Habermann、H. Uhlig、K. Wy�uwa

  DOI：10.1002/prac.19933350807

  日期：——

  The syntheses of alpha-methylated fencholenic (6a) and alpha-campholenic aldehyde (6b) via the corresponding azomethines (5) are reported. Aldol condensations of 6a, b with following reductions give the allylic alcohols (12-16) and hydrogenation the saturated alcohols (17-21) with strong woody odors, some of the allylic alcohols resembling that of sandal wood. Simple reduction or oxidation of 6a, b give the alcohols (24, 27), ethers (26), esters (23, 25, 28) and ketones (29) which have interesting woody odors with spicy, earthy and herbaceous notes.