A polymer stabilizer comprising the following alkoxy compound:
the alkoxy compound: a compound obtained by alkoxylating at least one hydroxyl group contained in a compound of the following formula (1) containing one formyl group or carbonyl group and (n−
1
) hydroxyl groups in the molecule with an alkyl group having 1 to 12 carbon atoms:
C
n
H
2n
O
n
(1)
(wherein, n represents an integer of 3 or more).
A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1
作者:Kumar Bhaskar Pal、Mukul Mahanti、Hakon Leffler、Ulf J. Nilsson
DOI:10.3390/ijms20153786
日期:——
inhibitors than natural ligand fragments. Here, we describe the synthesis and evaluation of 3-C-methyl-gulopyranoside derivatives and their evaluation as galectin inhibitors. Methyl 3-deoxy-3-C-(hydroxymethyl)-β-d-gulopyranoside showed 7-fold better affinity for galectin-1 than the natural monosaccharide fragment analog methylβ-d-galactopyranoside, as well as a high selectivity over galectin-2, 3, 4, 7,
General Strategy for the Synthesis of Rare Sugars via Ru(II)-Catalyzed and Boron-Mediated Selective Epimerization of 1,2-<i>trans</i>-Diols to 1,2-<i>cis</i>-Diols
作者:Xiaolei Li、Jicheng Wu、Weiping Tang
DOI:10.1021/jacs.1c13399
日期:2022.3.2
Although several methods have been developed for the synthesis of rare monosaccharides, most of them involve lengthy steps. Herein, we report an efficient and general strategy that can provide access to rare sugars from commercially available common monosaccharides via a one-step Ru(II)-catalyzed and boron-mediated selective epimerization of 1,2-trans-diols to 1,2-cis-diols. The formation of boronate esters
A polymer stabilizer comprising the following alkoxy compound:
the alkoxy compound: a compound obtained by alkoxylating at least one hydroxyl group contained in a compound of the following formula (1) containing one formyl group or carbonyl group and (n-1) hydroxyl groups in the molecule with an alkyl group having 1 to 12 carbon atoms:
CnH2nOn (1)
(wherein n represents an integer of 3 or more).