1,4-二碘-2-硝基苯 | 89488-57-3

• 物质功能分类: 有机原料 - 烃类化合物及其衍生物 - 烃类硝化物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,4-二碘-2-硝基苯
• 英文名称: 1,4-diiodo-2-nitrobenzene
• 英文别名: 2,4-diiodo-nitrobenzene；2,5-diiodonitrobenzene；1,4-diiodo-2-nitro-benzene；1,4-Dijod-2-nitro-benzol
• CAS: 89488-57-3
• 化学式: C₆H₃I₂NO₂
• mdl: MFCD09030977
• 分子量: 374.904
• InChiKey: WNAMUUCHNYHBEV-UHFFFAOYSA-N

物化性质

• 熔点：
  109-110℃
• 沸点：
  354.7±27.0 °C(Predicted)
• 密度：
  2.578±0.06 g/cm3 (20 ºC 760 Torr)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险性防范说明：
  P280,P305+P351+P338
• 危险性描述：
  H302
• 储存条件：
  室温且干燥环境中保存。

反应信息

• 作为反应物：
  描述：

  1,4-二碘-2-硝基苯 在 copper(l) iodide potassium carbonate 、 N,N-二异丙基乙胺 、 三苯基膦 、 bis(dibenzylideneacetone)-palladium⁽⁰⁾ 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 生成 1,4-二乙炔基-2-硝基苯
  参考文献：
  名称：

  Scanning Tunneling Microscopy of Self-Assembled Phenylene Ethynylene Oligomers on Au(111) Substrates

  摘要：

  In this paper, we report the self-assembly, electrical characterization, and surface modification of dithiolated phenylene-ethynylene oligomer monolayers on a Au(111) surface. The self-assembly was accomplished by thiol bonding the molecules from solution to a Au(111) surface. We have confirmed the formation of self-assembled monolayers by scanning tunneling microscopy (STM) and optical ellipsometry, and have studied the kinetics of film growth. We suggest that self-assembled phenylene ethynylene oligomers on Au(111) surfaces grow as thiols rather than as thiolates. Using low-temperature STM, we collected local current-voltage spectra showing negative differential resistance at 6 K.

  DOI：

  10.1021/ja036771v
• 作为产物：
  描述：

  4-碘-3-硝基苯胺 生成 1,4-二碘-2-硝基苯
  参考文献：
  名称：

  Koerner; Belasio, Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1908, vol. <5> 17 I, p. 688

  摘要：

  DOI：

文献信息

• Nucleotides and nucleosides and methods for their use in DNA sequencing
  申请人：Lasergen, Inc.

  公开号：US09200319B2

  公开（公告）日：2015-12-01

  The present invention relates generally to labeled and unlabled cleavable terminating groups and methods for DNA sequencing and other types of DNA analysis. More particularly, the invention relates in part to nucleotides and nucleosides with chemically cleavable, photocleavable, enzymatically cleavable, or non-photocleavable groups and methods for their use in DNA sequencing and its application in biomedical research.

  本发明一般涉及带标记和未标记的可切割终止基团以及用于DNA测序和其他类型的DNA分析的方法。更具体地，该发明部分涉及具有化学可切割、光解可切割、酶可切割或非光解可切割基团的核苷酸和核苷以及它们在DNA测序中的使用方法及其在生物医学研究中的应用。
• Regioselective Iodine/Zinc Exchange for the Selective Functionalization of Polyiodinated Arenes and Heterocycles in Toluene
  作者：Florian Sanchez、Alexandre Desaintjean、Paul Knochel、Fanny Danton

  DOI：10.1055/a-1559-3384

  日期：2021.12

  Regioselective I/Zn-exchange reactions were performed on polyiodinated arenes or heterocycles within 20 minutes at 0–25 °C using the bimetallic combination pTol2Zn·2LiOR [R = (CH2)2N(Me)(CH2)2NMe2] in toluene. The resulting diaryl- or diheteroarylzincs reacted well with allylic bromides and acyl chlorides to provide functionalized (hetero)aryl iodides in good yields.

  使用双金属组合 pTol2Zn·2LiOR [R = (CH2)2N(Me)(CH2)2NMe2] 在甲苯中，在 20 分钟内在 0–25 °C 下对多碘化芳烃或杂环进行区域选择性 I/Zn 交换反应。所得二芳基-或二杂芳基锌与烯丙基溴和酰氯反应良好，以良好的产率提供官能化的（杂）芳基碘化物。
• PROCESS FOR PREPARING 6-IODO-2-OXINDOLE
  申请人：SHI Wenjian

  公开号：US20140066634A1

  公开（公告）日：2014-03-06

  Disclosed is a method for the synthesis of 6-iodo-2-oxindole useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed is a novel intermediate used in the synthesis of this compound.

  公开了一种合成6-碘-2-氧吲哚的方法，该方法可用作制药活性成分制造中间体。还公开了用于合成该化合物的新型中间体。
• [EN] PROCESS FOR PREPARING 6-IODO-2-OXINDOLE<br/>[FR] PROCÉDÉ DE PRÉPARATION DE 6-IODO -2-OXINDOLE
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2014037307A1

  公开（公告）日：2014-03-13

  Disclosed is a method for the synthesis of 6-iodo-2-oxindole useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed is a novel intermediate used in the synthesis of this compound.

  公开了一种合成6-碘-2-氧吲哚的方法，该方法可用作制药活性成分的中间体。还公开了用于合成该化合物的一种新型中间体。
• Novel compounds and their manufacture and use
  申请人：——

  公开号：US20020041976A1

  公开（公告）日：2002-04-11

  Benzofuran, benzothiophene or indole oligomers, co-oligomers, polymers and copolymers, methods for their production, and their use in charge transport and light emission regions of electroluminescent devices are described.

  本文介绍苯并呋喃、苯并硫吡啶或吲哚低聚物、共低聚物、聚合物和共聚物的制备方法，以及它们在电致发光器件的电荷传输和发光区域中的应用。