4-环己基雷琐辛 | 2138-20-7

• 物质功能分类: 有机原料 - 烃类化合物及其衍生物 - 芳香烃
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-环己基雷琐辛
• 英文名称: 4-cyclohexylresorcinol
• 英文别名: 4-cyclohexylbenzene-1,3-diol
• CAS: 2138-20-7
• 化学式: C₁₂H₁₆O₂
• mdl: MFCD00019336
• 分子量: 192.258
• InChiKey: LSEHCENPUMUIKC-UHFFFAOYSA-N

物化性质

• 熔点：
  124 °C
• 沸点：
  288.25°C (rough estimate)
• 密度：
  1.0240 (rough estimate)
• 溶解度：
  0.00 M
• 保留指数：
  1663

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• 海关编码：
  2907299090

反应信息

• 作为反应物：
  描述：

  4-环己基雷琐辛 在 磺酰氯 、 乙醚 作用下， 生成 4-chloro-6-cyclohexyl-resorcinol
  参考文献：
  名称：

  Tomita et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1949, vol. 69, p. 151,153

  摘要：

  DOI：
• 作为产物：
  描述：

  4-chloro-6-cyclohexyl-resorcinol 在 palladium on activated charcoal 、 磺酰氯 、 乙醇 、 溶剂黄146 作用下， 生成 4-环己基雷琐辛
  参考文献：
  名称：

  Tomita et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1951, vol. 71, p. 1012

  摘要：

  DOI：

文献信息

• PREPARATION COMPRISING CHROMAN-2-ONE DERIVATIVES
  申请人：Mujica-Fernaud Teresa

  公开号：US20100291009A1

  公开（公告）日：2010-11-18

  The invention relates to preparations comprising at least one compound of the formula (I), where the substituents R 1 to R 4 have a meaning indicated in claim 1 , and salts and solvates thereof, and to the use thereof and selected compounds of the formula (I).

  该发明涉及包含至少一种式(I)化合物的制剂，其中取代基R1至R4具有权利要求1中指示的含义，以及其盐和溶剂合物，以及其用途和选择的式(I)化合物。
• COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES
  申请人：Conopco, Inc., d/b/a UNILEVER

  公开号：US20160008249A1

  公开（公告）日：2016-01-14

  The invention is directed to a cosmetic composition and the precursor thereof. The composition has solid agent and liquid agent, both of which are cosmetic benefit ingredients. The solubility of solid agents in liquid agents in the inventive compositions is enhanced in the presence of a tricyclodecane amide.

  该发明涉及一种化妆品组合物及其前体。该组合物具有固体剂和液体剂，两者均为化妆品益处成分。在创新组合物中，固体剂在液体剂中的溶解性在三环十二碳酰胺的存在下得到增强。
• 4-Alkylresorcinol Derivative And External Preparation For Skin Containing The Same
  申请人：Fukunishi Hirotada

  公开号：US20130109878A1

  公开（公告）日：2013-05-02

  The present invention provides a compound that has a high whitening effect and is excellent in safety and stability and provides an external preparation for skin comprising the same. The compound of the present invention is a 4-alkylresorcinol derivative represented by formula (1) or a salt thereof: wherein R 1 is a branched or cyclic alkyl group of 3 to 7 carbon atoms or a linear alkyl group of 2 to 5 carbon atoms; R 2 and R 3 are each independently a hydrogen atom or a group represented by —P(O)(OR 4 )(OR 5 ), and at least one of R 2 and R 3 is a group represented by —P(O)(OR 4 )(OR 5 ); and R 4 and R 5 are each independently a hydrogen atom or a linear or branched alkyl group of 2 to 5 carbon atoms.

  本发明提供了一种具有高美白效果、安全稳定性优异的化合物，并提供了包括该化合物的皮肤外用制剂。本发明的化合物是一种4-烷基间苯二酚衍生物，其化学式表示为（1）或其盐：其中，R1是由3至7个碳原子组成的支链或环烷基，或由2至5个碳原子组成的直链烷基；R2和R3各自独立地是氢原子或由—P(O)(OR4)(OR5)表示的基团，且R2和R3中至少一个是由—P(O)(OR4)(OR5)表示的基团；R4和R5各自独立地是氢原子或由2至5个碳原子组成的直链或支链烷基。
• MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME
  申请人：TABATA Masayoshi

  公开号：US20110224343A1

  公开（公告）日：2011-09-15

  The present invention provides a modifier for aromatic polyesters which enhances the melt fluidity of aromatic polyesters without a significant decrease in the heat resistance of the aromatic polyesters, and an aromatic polyester resin composition including the modifier for aromatic polyesters. The present invention relates to a modifier for aromatic polyesters comprising polyhydric phenol residues and residues of aromatic polycarboxylic acid, acid halide or acid anhydride thereof, and the modifier comprises a material having a structure composed of a first residue selected from the group consisting of divalent residues represented by Formula (I): —Ar—W 1 x —Ar— and by Formula (II): —Ar—, the first residues being bonded to two identical or different second residues selected from the group consisting of monovalent residues represented by Formula (III): and monovalent residues represented by Formula (IV): —O—C(O)—R 7 —.

  本发明提供了一种用于芳香族聚酯的改性剂，可以增强芳香族聚酯的熔融流动性，而不明显降低芳香族聚酯的耐热性，以及包括该改性剂的芳香族聚酯树脂组合物。本发明涉及一种用于芳香族聚酯的改性剂，包括多羟基酚残基和芳香族多羧酸、酸卤或其酸酐残基，该改性剂包括具有以下结构的材料：第一残基，选择自由式(I)所代表的二价残基：—Ar—W1x—Ar—和自由式(II)所代表的：—Ar—，第一残基与选择自由式(III)所代表的单价残基：和自由式(IV)所代表的单价残基：—O—C(O)—R7—的两个相同或不同的第二残基结合。
• Abnormal Cannabidiols as agents for lowering intraocular pressure
  申请人：Chen June

  公开号：US20070249581A1

  公开（公告）日：2007-10-25

  The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R 1 and R 2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.

  本发明提供了一种治疗青光眼或眼压增高的方法，包括向需要该方法的人的眼睛施加足够治疗青光眼或眼压增高的化合物I的数量，其中Y、Q、Z、R、R1和R2如规范中所定义。本发明还包括药物组合物，例如眼科组合物，包括上述化合物I。

表征谱图