phytanyl hemisuccinate | 199484-61-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: phytanyl hemisuccinate
• 英文别名: 4-oxo-4-[(7R,11R)-3,7,11,15-tetramethylhexadecoxy]butanoic acid
• CAS: 199484-61-2
• 化学式: C₂₄H₄₆O₄
• 分子量: 398.627
• InChiKey: IZZBLNKAMCUUHT-JAZPPYFYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  28
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  phytanyl hemisuccinate 在 palladium on activated charcoal 4-二甲氨基吡啶 、 Morpho-CDI 、 氢气 作用下， 以 吡啶 、 乙醇 、 二氯甲烷 为溶剂， 反应 116.0h， 生成 (phytanyl heptaethylene glycol succinate) hemisuccinate
  参考文献：
  名称：

  摘要：

  In order to optimize the performance of the AMBRI(TM) biosensor (Nature 1997, 387, 580), a variety of hydrophilic linkers between the hydrophobic bilayer membrane and the gold surface have been synthesized. The principal components are prepared from phytanyl hemisuccinate, which is linked by repeating ethylene glycol or propylene glycol units to a second succinic acid unit. The syntheses of analogous substances in which the ester links are replaced by amide and by ether links are also described.

  DOI：

  10.1071/ch01111
• 作为产物：
  描述：

  丁二酸酐 、 2,3-dihydrophytol 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以97%的产率得到phytanyl hemisuccinate
  参考文献：
  名称：

  摘要：

  In order to optimize the performance of the AMBRI(TM) biosensor (Nature 1997, 387, 580), a variety of hydrophilic linkers between the hydrophobic bilayer membrane and the gold surface have been synthesized. The principal components are prepared from phytanyl hemisuccinate, which is linked by repeating ethylene glycol or propylene glycol units to a second succinic acid unit. The syntheses of analogous substances in which the ester links are replaced by amide and by ether links are also described.

  DOI：

  10.1071/ch01111