十六烷基酸-1,2-亚乙基酯 | 624-03-3

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 十六烷基酸-1,2-亚乙基酯
• 英文名称: ethylene glycol dipalmitate
• 英文别名: ethane-1,2-diyl dihexadecanoate；Aethylenglycoldipalmitat；1,2-Dipalmitoyloxy-ethan；Ethylenglykol-dipalmitat；1,2-O-Dihexadecanoyl-1,2-ethandiol；hexadecanoic acid, 1,2-ethanediyl ester；1,2-Di-O-hexadecanoyl-ethandiol；1,2-Bis-palmitoyloxy-aethan；1,2-bis-palmitoyloxy-ethane；glycol dipalmitate；polyethylene glycol dipalmitate；ethane-1,2-diyl palmitate；2-hexadecanoyloxyethyl hexadecanoate
• CAS: 624-03-3
• 化学式: C₃₄H₆₆O₄
• 分子量: 538.896
• InChiKey: IKVCSHRLYCDSFD-UHFFFAOYSA-N

物化性质

• 熔点：
  72°C
• 沸点：
  535°C (rough estimate)
• 密度：
  0.8594
• 溶解度：
  氯仿：30mg/mL
• LogP：
  14.820 (est)
• 保留指数：
  3656

计算性质

• 辛醇/水分配系数(LogP)：
  14.7
• 重原子数：
  38
• 可旋转键数：
  33
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

反应信息

• 作为产物：
  描述：

  potassium palmitate 、 1,2-二氯乙烷 生成 十六烷基酸-1,2-亚乙基酯
  参考文献：
  名称：

  Krafft, Chemische Berichte, 1903, vol. 36, p. 4341

  摘要：

  DOI：

文献信息

• Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome
  申请人：Panzner Steffen

  公开号：US20080089932A1

  公开（公告）日：2008-04-17

  An amphoteric liposome composed of a mixture of lipids, said mixture comprising a cationic amphiphile, an anionic amphiphile and optionally one or more neutral amphiphiles, at least one of said cationic and anionic amphiphiles being chargeable and the respective amounts of said cationic and anionic amphiphiles being selected such there is a stoichiometric excess of positively charged cationic amphiphile at a first lower pH, a stoichiometric excess of negatively charged anionic amphiphile at a second higher pH and said mixture has an isoelectric point intermediate said first and second pHs; characterised in that said positively charged cationic and negatively charged anionic amphiphiles are adapted to form a lipid salt with one another at said isoelectric point. Also disclosed are methods of predicting the fusogenicity of an amphoteric liposome at a given pH, formulating an amphoteric liposome and loading an amphoteric liposome with a cargo moiety.

  一种由混合脂质组成的两性脂质体，所述混合物包括阳离子型两性分子、阴离子型两性分子和可选的一种或多种中性两性分子，其中至少一种阳离子型和阴离子型两性分子可被电荷化，所述阳离子型和阴离子型两性分子的相应量被选择为在第一个较低的pH下具有过量的正电荷的阳离子型两性分子，在第二个较高的pH下具有过量的负电荷的阴离子型两性分子，且所述混合物具有介于第一个和第二个pH之间的等电点；其特征在于所述的阳离子型和阴离子型两性分子适合在所述等电点处彼此形成脂质盐。还公开了预测给定pH下两性脂质体的融合性、制备两性脂质体和将载荷基团装载到两性脂质体中的方法。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• LUBRICANT FOR THERMOPLASTIC POLYMERS
  申请人：Daute Peter

  公开号：US20120005991A1

  公开（公告）日：2012-01-12

  The invention relates to a polymer composition, comprising at least one thermoplastic polymer, at least one pigment or at least one filler or a mixture thereof and at least one diester of a linear diol having 2 to 8 C-atoms with a linear or branched, saturated or unsaturated monocarboxylic acid having 6 to 44 C-atoms, wherein the fraction of diesters comprising different fatty acid radicals in a molecule is less than 10% by weight with regard to the total amount of diesters.

  本发明涉及一种聚合物组合物，包括至少一种热塑性聚合物、至少一种颜料或至少一种填料或其混合物和至少一种具有2至8个碳原子的线性二元醇的二酯，其与具有6至44个碳原子的线性或支链、饱和或不饱和的一元羧酸反应，其中分子中含有不同脂肪酸基的二酯的比例相对于二酯的总量重量小于10%。
• Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome
  申请人：Panzner Steffen

  公开号：US20120135065A1

  公开（公告）日：2012-05-31

  An amphoteric liposome composed of a mixture of lipids, said mixture comprising a cationic amphiphile, an anionic amphiphile and optionally one or more neutral amphiphiles, at least one of said cationic and anionic amphiphiles being chargeable and the respective amounts of said cationic and anionic amphiphiles being selected such there is a stoichiometric excess of positively charged cationic amphiphile at a first lower pH, a stoichiometric excess of negatively charged anionic amphiphile at a second higher pH and said mixture has an isoelectric point intermediate said first and second pHs; characterised in that said positively charged cationic and negatively charged anionic amphiphiles are adapted to form a lipid salt with one another at said isoelectric point. Also disclosed are methods of predicting the fusogenicity of an amphoteric liposome at a given pH, formulating an amphoteric liposome and loading an amphoteric liposome with a cargo moiety.

  一种两性脂质体，由混合脂质组成，所述混合物包括阳离子两性分子、阴离子两性分子和可选的一个或多个中性两性分子，其中至少一种阳离子和阴离子两性分子是可带电的，并且所述阳离子和阴离子两性分子的相应量被选择为在第一个较低的pH值下存在过量的带正电荷的阳离子两性分子，在第二个较高的pH值下存在过量的带负电荷的阴离子两性分子，并且所述混合物具有介于第一个和第二个pH值之间的等电点；其特征在于所述带正电荷的阳离子和带负电荷的阴离子两性分子被适应在所述等电点处彼此形成脂质盐。还公开了预测在给定pH下两性脂质体的融合性、制备两性脂质体和将载荷基团装载到两性脂质体中的方法。
• Lubricant for thermoplastic polymers
  申请人：Daute Peter

  公开号：US09096738B2

  公开（公告）日：2015-08-04

  The invention relates to a polymer composition, comprising at least one thermoplastic polymer, at least one pigment or at least one filler or a mixture thereof and at least one diester of a linear diol having 2 to 8 C-atoms with a linear or branched, saturated or unsaturated monocarboxylic acid having 6 to 44 C-atoms, wherein the fraction of diesters comprising different fatty acid radicals in a molecule is less than 10% by weight with regard to the total amount of diesters.

  本发明涉及一种聚合物组合物，包括至少一种热塑性聚合物，至少一种颜料或至少一种填料或其混合物，以及至少一种具有2到8个C原子的线性二元醇的二酯，其与具有6到44个C原子的线性或支链饱和或不饱和单羧酸反应，其中分子中含有不同脂肪酸基团的二酯的比例相对于总二酯量小于10%。

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