O-ethyl [(10-methyl-10H-acridin-9-ylidene)amino]carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: O-ethyl [(10-methyl-10H-acridin-9-ylidene)amino]carboxylate
• 英文别名: N-(10-methylacridin-9-ylidene)carbamic acid ethyl ester；ethyl N-(10-methylacridin-9-ylidene)carbamate
• 化学式: C₁₇H₁₆N₂O₂
• 分子量: 280.326
• InChiKey: QWMQHTUWTCIJFW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  41.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氟苯腈 在 potassium tert-butylate 、 叔丁基锂 作用下， 以 四氢呋喃 、 二甲基亚砜 、 正戊烷 为溶剂， 反应 2.0h， 生成 O-ethyl [(10-methyl-10H-acridin-9-ylidene)amino]carboxylate
  参考文献：
  名称：

  Synthesis of Pentacyclic 13-Azadibenzo[a,de]anthracenes via Anionic Cascade Ring Closure

  摘要：

  Bromine-lithium exchange using tert-butyllithium at -78 degreesC initiates a cascade process whereby either xanthone derivatives or pentacyclic 13-azadibenzo[a,de]-anthracenes are produced in high yields. The reaction proceeds via a sequential intramolecular trapping of organolithium intermediates.

  DOI：

  10.1021/jo0300340

文献信息

• New Approach to Synthesis of N-Substituted 9-Amino/Iminoacridines with Important Fluorescence Properties
  作者：Pavol Kristian、Juraj Bernát、Ján Imrich、Erik Sedlák、Juraj Alföldi、Michal Cornanic

  DOI：10.3987/com-00-9081

  日期：——

  In order to obtain new fluorogens simple versatile methods of synthesis of some O-alkyl [(10-methylacridinium-9-yl)amino]methanethioate trifluoromethanesulfonates, O-alkyl [(10-methyl-10H-acridin-9-ylidene)amino]methanethioates and O-alkyl [(10-methyl-10H-acridin-9-ylidene)amino]carboxylates were elaborated. The fluorescence properties of compounds under study were discussed.
• Synthesis of Pentacyclic 13-Azadibenzo[<i>a</i>,<i>d</i><i>e</i>]anthracenes via Anionic Cascade Ring Closure
  作者：Jesper L. Kristensen、Per Vedsø、Mikael Begtrup

  DOI：10.1021/jo0300340

  日期：2003.5.1

  Bromine-lithium exchange using tert-butyllithium at -78 degreesC initiates a cascade process whereby either xanthone derivatives or pentacyclic 13-azadibenzo[a,de]-anthracenes are produced in high yields. The reaction proceeds via a sequential intramolecular trapping of organolithium intermediates.