单丙酸甘油酯 | 624-47-5

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 中文名称: 单丙酸甘油酯
• 英文名称: glyceryl monopropionate
• 英文别名: 2,3-Dihydroxypropyl propionate；2,3-dihydroxypropyl propanoate
• CAS: 624-47-5；26894-50-8
• 化学式: C₆H₁₂O₄
• 分子量: 148.159
• InChiKey: AALUCPRYHRPMAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2915509000

反应信息

• 作为反应物：
  描述：

  单丙酸甘油酯 在 吡啶 、 三氯氧磷 作用下， 以 四氢呋喃 为溶剂， 反应 2.67h， 以86%的产率得到1-O-propanoyl-cyclophosphatidic acid potassium
  参考文献：
  名称：

  Discovery of Lipids from B. longum subsp. infantis using Whole Cell MALDI Analysis

  摘要：

  Bifidobacteria are dominant members of the microbial community in the intestinal tract of infants, and studies have shown that glycolipids extracted from the cell surface of these bacteria elicit beneficial immune responses. Accordingly, the identification and structural characterization of glycolipids from the cell wall of bifidobacteria is the first step in correlating glycolipid structure with biological activity. Using whole cell MALDI as a screening tool, we herein present for the first time the identification and structural elucidation of the major polar lipids from Bifidobacterium longum subs. infantis. The lipids identified include an unprecedented plasmenyl cyclophosphatidic acid and a mixed acetal glycolipid, with the latter subsequently being isolated and found to suppress the innate immune response.

  DOI：

  10.1021/jo501016c
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 水 、 溶剂黄146 作用下， 生成 单丙酸甘油酯
  参考文献：
  名称：

  脂肪分解酶作用的研究。三，水解三丙酰甘油。

  摘要：

  DOI：

  10.1016/0006-3002(52)90066-8

文献信息

• Design of a highly active silver-exchanged phosphotungstic acid catalyst for glycerol esterification with acetic acid
  作者：Shanhui Zhu、Xiaoqing Gao、Fang Dong、Yulei Zhu、Hongyan Zheng、Yongwang Li

  DOI：10.1016/j.jcat.2013.06.026

  日期：2013.10

  A series of highly active, selective, and stable silver-exchanged phosphotungstic acid (AgPW) catalysts were prepared, characterized, and evaluated for bio-derived glycerol esterification with acetic acid to produce valuable biofuel additives. The structures, morphologies, acidities, and water tolerance of these samples were determined by FTIR, Raman, XRD, SEM-EDX, FT-IR of pyridine adsorption, and

  制备，表征和评估了一系列高活性，选择性和稳定的银交换磷钨酸（AgPW）催化剂，以评估乙酸对生物衍生甘油的酯化反应，从而制得有价值的生物燃料添加剂。通过FTIR，拉曼，XRD，SEM-EDX，吡啶吸附的FT-IR和H 2 O-TPD确定这些样品的结构，形态，酸度和耐水性。还进行了几种典型的酸性催化剂的比较。其中，部分是银交换的磷钨酸（Ag 1PW）具有独特的高活性，由于独特的Keggin结构，高酸度和出色的耐水性，在短短15分钟的反应时间内即可实现96.8％的转化率和出色的稳定性。还提出了合理的反应机理。此外，这种Ag 1 PW催化剂对酯化反应具有普遍意义，在其他广泛的酸催化反应中也具有巨大潜力。
• Compositions and methods for enhancing phagocytosis or phagocyte activity
  申请人：Francois Cedric

  公开号：US20050113297A1

  公开（公告）日：2005-05-26

  The present invention provides a system for enhancing clearance or destruction of undesirable cells or noncellular molecular entities by tagging such cells or noncellular molecular entities with a marker that targets the cells or noncellular molecular entities for phagocytosis (phagocytic marker). The target cells can be, for example, endothelial cells, tumor cells, leukocytes, or virus-infected cells. In certain embodiments of the invention the tagging is accomplished by administering a composition comprising an antibody or ligand linked to the phagcytotic marker, wherein the antibody or ligand binds to a cell type specific marker present on or in the cell surface of a target cell. In preferred embodiments of the invention, the phagocytic marker comprises phosphatidylserine or a group derived from phosphatidylserine, thrombospondin-1, annexin I, or a derivative of any of these.

  本发明提供了一种系统，通过标记这些细胞或非细胞分子实体，以增强清除或破坏不良细胞或非细胞分子实体，从而使这些细胞或非细胞分子实体成为吞噬细胞的目标（吞噬标记）。目标细胞可以是内皮细胞、肿瘤细胞、白细胞或病毒感染的细胞，例如。在本发明的某些实施例中，通过给予含有与吞噬标记连接的抗体或配体的组合物来实现标记，其中抗体或配体结合到目标细胞的细胞特异性标记，该标记存在于目标细胞的细胞表面或内部。在本发明的优选实施例中，吞噬标记包括磷脂酰丝氨酸或磷脂酰丝氨酸衍生物、血栓调节蛋白-1、骨桥蛋白I或这些任何一种的衍生物。
• (2,3-二氢噻吩并[3,4-B][1,4]二氧杂环己-2-基)甲醇的制备方法
  申请人：福建博鸿新能源科技有限公司

  公开号：CN110183465A

  公开（公告）日：2019-08-30

  本发明公开(2,3‑二氢噻吩并[3,4‑B][1,4]二氧杂环己‑2‑基)甲醇的制备方法，其包括以下步骤：以3,4‑二烷氧基噻吩‑2,5‑二甲酸二烷基酯和单烷酸甘油酯为原料进行得到中间物1，再将中间物1进行碱化酸化反应得到中间物2，最后将中间物2进行脱羧后精馏得到产品。本发明由于单烷酸甘油酯只有两个醇羟基进行交换反应，使得合成的产物中间体1没有异构体杂质产生，从而可减少工业分离工序，产品的收率高，生产成本低，有利于工业化生产。
• POLYOL ESTER COMPOUNDS
  申请人：Lorbert Stephen J.

  公开号：US20070292485A1

  公开（公告）日：2007-12-20

  Disclosed are polyol esters comprising a polyol having at least one hydroxyl group esterified to at least one compound having a carboxyl group. Methods of making the polyol ester compounds are also disclosed. The invention also relates to feed compositions comprising polyol ester compounds.

  本发明涉及聚醇酯，其包括至少有一个羟基酯化至至少一个具有羧基的化合物的聚醇。还公开了制备聚醇酯化合物的方法。本发明还涉及包含聚醇酯化合物的饲料组合物。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。

表征谱图