cycloprop[d]indolo[2,1-a][2]benzazepine-1a, 5(2H)-dicarboxylic acid, 8-cyclohexyl-1,12b-dihydro-11-methoxy-, 5-(1,1-dimethylethyl) 1a-methyl ester, (+/-)

分子结构分类

有机化合物 - 有机杂环化合物 - 吲哚及其衍生物

中文名称

——

中文别名

——

英文名称

cycloprop[d]indolo[2,1-a][2]benzazepine-1a, 5(2H)-dicarboxylic acid, 8-cyclohexyl-1,12b-dihydro-11-methoxy-, 5-(1,1-dimethylethyl) 1a-methyl ester, (+/-)

英文别名

cycloprop[d]indolo[2,1-a][2]benzazepine-1a,5(2H)-dicarboxylic acid, 8-cyclohexyl-1,12b-dihydro-11-methoxy-, 5-(1,1-dimethylethyl) 1a-methyl ester, (+/-)；cycloprop[d]indolo[2,1-a][2]benzazepine-1a,5(2H)-dicarboxylic acid, 8-cyclohexyl-1,12b-dihydro-11-methoxy-, 5-(1,1-dimethylethyl)1a-methyl ester, (+/-)；(+/-)-cycloprop[d]indolo[2,1-a][2]benzazepine-1a,5(2H)-dicarboxylic acid, 8-cyclohexyl-1,12b-dihydro-11-methoxy-, 5-(1,1-dimethylethyl)1a-methyl ester；(+/-)-8-cyclohexyl-1,12b-dihydro-11-methoxy-5-(1,1-dimethylethyl)-cycloprop[d]indolo[2,1-a][2]benzazepine-1a,5(2H)-dicarboxylic acid 1a-methyl ester；(+/-)-8-cyclohexyl-1,12b-dihydro-11-methoxy-cycloprop[d]indolo[2,1-a][2]benzazepine-1a,5(2H)-dicarboxylic acid 5-(1,1-dimethylethyl) 1a-methyl ester；5-(1,1-dimethylethyl) 1a-methyl (+/-)-8-cyclohexyl-11-(methyloxy)-1,12b-dihydrocyclopropa[d]indolo[2,1-a][2]benzazepine-1a,5(2H)-dicarboxylate；15-O-tert-butyl 10-O-methyl 19-cyclohexyl-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-10,15-dicarboxylate

cycloprop[d]indolo[2,1-a][2]benzazepine-1a, 5(2H)-dicarboxylic acid, 8-cyclohexyl-1,12b-dihydro-11-methoxy-, 5-(1,1-dimethylethyl) 1a-methyl ester, (+/-)化学式

CAS

——

化学式

C₃₂H₃₇NO₅

mdl

——

分子量

515.649

InChiKey

YFSJLPIPBPSXCB-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

6.6
重原子数：

38
可旋转键数：

7
环数：

6.0
sp3杂化的碳原子比例：

0.5
拓扑面积：

66.8
氢给体数：

0
氢受体数：

5

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid 10-(1,1-dimethylethyl) ester 6-methyl ester	928844-30-8	C₃₁H₃₅NO₅	501.623
——	13-cyclohexyl-7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid 10-(1,1-dimethylethyl) 6-methyl ester	1045704-98-0	C₃₀H₃₃NO₄	471.596
——	13-cyclohexyl-10-[[[(dimethylamino)sulfonyl]amino]carbonyl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-6-carboxylic acid methyl ester	902148-54-3	C₂₉H₃₃N₃O₆S	551.664
——	6H-Isoindolo[2,1-a]indole-3-carboxamide, 11-cyclohexyl-N-[(dimethylamino)sulfonyl]-6-ethoxy-8-methoxy-	958002-14-7	C₂₇H₃₃N₃O₅S	511.642
3-环己基-2-(2-甲酰基-4-甲氧基苯基)-1H-吲哚-6-羧酸1,1-二甲基乙基酯	1H-indole-6-carboxylic acid, 3-cyclohexyl-2-(2-formyl-4-methoxyphenyl)-, 1,1-dimethylethyl ester	958002-18-1	C₂₇H₃₁NO₄	433.547
——	3-cyclohexyl-N-[(dimethylamino)sulfonyl]-2-(2-formyl-4-methoxyphenyl)-1H-indole-6-carboxamide	928844-26-2	C₂₅H₂₉N₃O₅S	483.588
——	tert-butyl 3-cyclohexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-6-carboxylate	1204417-91-3	C₂₅H₃₆BNO₄	425.376

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	(+/-)-8-cyclohexyl-11-(methyloxy)-1a-((methyloxy)carbonyl)-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxylic acid	1033906-14-7	C₂₈H₂₉NO₅	459.542
——	(4bR,5aS)-9-(tert-butoxycarbonyl)-12-cyclohexyl-3-methoxy-4b,5,5a,6-tetrahydrobenzo[3,4]cyclopropa[5,6]azepino-[1,2-a]indole-5a-carboxylic acid	1059700-79-6	C₃₁H₃₅NO₅	501.623
——	(4bR,5aS)-9-(tert-butoxycarbonyl)-12-cyclohexyl-3-methoxy-4b,5,5a,6-tetrahydrobenzo[3,4]cyclopropa[5,6]azepino[1,2-a]indole-5a-carboxylic acid	1204417-51-5	C₃₁H₃₅NO₅	501.623
——	Methyl 19-cyclohexyl-5-methoxy-15-(methylsulfonylcarbamoyl)-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-10-carboxylate	1033905-37-1	C₂₉H₃₂N₂O₆S	536.649
——	(+/-)-8-cyclohexyl-5-[[[(methylamino)sulfonyl]amino]carbonyl]-1,2b-dihydro-11-methoxy-cycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid methyl ester	1033906-16-9	C₂₉H₃₃N₃O₆S	551.664
——	(+/-)-8-cyclohexyl-5-[[(benzylamino)sulfonyl]amino]carbonyl-1,12b-dihydro-11-(methoxy)-12-(methoxy)-cycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid methyl ester	1033906-20-5	C₃₅H₃₇N₃O₆S	627.761
——	(+/-)-8-cyclohexyl-5-[[[(dimethylamino)sulfonyl]amino]carbonyl]-1,12b-dihydro-11-methoxy-cycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid methyl ester	959983-21-2	C₃₀H₃₅N₃O₆S	565.69
——	methyl 8-cyclohexyl-5-((cyclopropylsulfonyl)carbamoyl)-1,1-methoxy-1,12b-dihydrocyclopropa[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylate	1033906-24-9	C₃₁H₃₄N₂O₆S	562.687
——	8-cyclohexyl-5-[[(methylsulfonyl)amino]carbonyl]-1,12b-dihydro-11-methoxy-cycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid	1033905-34-8	C₂₈H₃₀N₂O₆S	522.622
——	(+/-)-8-cyclohexyl-5-[[[(methylamino)sulfonyl]amino]carbonyl]-1,2b-dihydro-11-methoxy-cycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid	1033906-18-1	C₂₈H₃₁N₃O₆S	537.637
——	Tert-butyl 10-carbonochloridoyl-19-cyclohexyl-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxylate	1204417-44-6	C₃₁H₃₄ClNO₄	520.068
——	(-) cycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid, 8-cyclohexyl-5-[[[(dimethylamino)sulfonyl]amino]carbonyl]-1,12b-dihydro-11-methoxy-	959983-22-3	C₂₉H₃₃N₃O₆S	551.664
——	(1aR,12bS)-8-cyclohexyl-5-[[[(dimethylamino)sulfonyl]amino]carbonyl]-1,12b-dihydro-11-methoxycycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid	928843-71-4	C₂₉H₃₃N₃O₆S	551.664
——	(1aS,12bR)-8-cyclohexyl-5-[[[(dimethylamino)sulfonyl]amino]carbonyl]-1,12b-dihydro-11-methoxycycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid methyl ester	——	C₂₉H₃₃N₃O₆S	551.664
——	(+/-)-cycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid, 8-cyclohexyl-5-[[(cyclopropylsulfonyl)amino]carbonyl]-1,12b-dihydro-11-methoxy-	——	C₃₀H₃₂N₂O₆S	548.66
——	tert-butyl (1aS,12bR)-8-cyclohexyl-11-methoxy-1a-(methyl{2-[2-(methylamino)ethoxy]ethyl}carbamoyl)-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxylate	1204417-52-6	C₃₇H₄₉N₃O₅	615.813
——	tert-butyl (1aR,12bS)-8-cyclohexyl-11-methoxy-1a-(methyl{2-[2-(methylamino)ethoxy]ethyl}carbamoyl)-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxylate	1204417-48-0	C₃₇H₄₉N₃O₅	615.813
——	(+/-)-8-cyclohexyl-N-(dimethylaminosulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-[(morpholine-4-carbonyloxy)methyl]-cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide	1058073-42-9	C₃₄H₄₂N₄O₇S	650.796
——	tert-butyl (1aS,12bR)-1a-[(2-{2-[(aminosulfonyl)(methyl)amino]-ethoxy}ethyl)(methyl)carbamoyl]-8-cyclohexyl-11-methoxy-1,1a,2,12b-tetrahydro-cyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxylate	1204417-53-7	C₃₇H₅₀N₄O₇S	694.893
——	(+/-)-8-cyclohexyl-N-(dimethylaminosulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-(hydroxymethyl)-cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide	1058073-32-7	C₂₉H₃₅N₃O₅S	537.68
——	(1aS,12bR)-1a-[(2-{2-[(aminosulfonyl)(methyl)amino]ethoxy}ethyl)(methyl)carbamoyl]-8-cyclohexyl-11-methoxy-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxylic acid	1204417-54-8	C₃₃H₄₂N₄O₇S	638.785
——	(1aR,12bS)-1a-[(2-{2-[(aminosulfonyl)(methyl)amino]ethoxy}ethyl)(methyl)carbamoyl]-8-cyclohexyl-11-methoxy-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxylic acid	1204417-50-4	C₃₃H₄₂N₄O₇S	638.785
——	(+/-)-8-cyclohexyl-N-(dimethylaminosulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-(chloromethyl)-cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide	1058073-37-2	C₂₉H₃₄ClN₃O₄S	556.126
——	(1aR,12bS)-8-cyclohexyl-11-methoxy-16,22-dimethyl-1,12b-dihydro-5,1a-(methanoiminothioiminoethanooxyethanoiminomethano)cyclopropa[d]indolo[2,1-a][2]benzazepine-13,23(2H)-dione 15,15-dioxide	1204417-04-8	C₃₃H₄₀N₄O₆S	620.77
——	(1aS,12bR)-8-cyclohexyl-11-methoxy-16,22-dimethyl-1,12b-dihydro-5,1a-(methanoiminothioiminoethanooxyethanoiminomethano)cyclopropa[d]indolo [2,1-a][2]benzazepine-13,23(2H)-dione 15,15-dioxide	1204600-90-7	C₃₃H₄₀N₄O₆S	620.77
——	(+/-)-8-cyclohexyl-N-(dimethylaminosulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-(morpholinomethyl)-cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide	1058073-47-4	C₃₃H₄₂N₄O₅S	606.786
——	1a-(((4aS,7aS)-6-benzyloctahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)carbonyl)-8-cyclohexyl-N-(cyclopropylsulfonyl)-11-methoxy-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide	1059609-16-3	C₄₄H₅₀N₄O₅S	746.971