靛红联二甲酚 | 47465-97-4

• 物质功能分类: 化学试剂 - 有机试剂 - 芳香酮
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: 靛红联二甲酚
• 中文别名: 1,3-二氢-3,3-双(4-羟基-3-甲苯基)-2H-吲哚-2-酮
• 英文名称: 3,3-bis(4-hydroxy-3-methylphenyl)-1H-indol-2-one
• 英文别名: 3,3-bis(4-hydroxy-3-methylphenyl)indolin-2-one；3,3-Bis-(4-hydroxy-3-methyl-phenyl)-indolin-2-on；1,3-dihydro-3,3-bis(4-hydroxy-m-tolyl)-2H-indol-2-one；2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxy-3-methylphenyl)-
• CAS: 47465-97-4
• 化学式: C₂₂H₁₉NO₃
• 分子量: 345.398
• InChiKey: ZEKCYPANSOJWDH-UHFFFAOYSA-N

物化性质

• 熔点：
  250-251°C
• 沸点：
  560.4±50.0 °C(Predicted)
• 密度：
  1.292±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• 安全说明：
  S26,S36,S36/37
• 危险类别码：
  R20/21/22,R36/37/38
• 海关编码：
  2933790090
• 危险品标志：
  Xi
• WGK Germany：
  2
• RTECS号：
  SL7940000

反应信息

• 作为反应物：
  描述：

  靛红联二甲酚 在 硝酸 、 溶剂黄146 作用下， 生成 3,3-bis-(4-hydroxy-3-methyl-5-nitro-phenyl)-indolin-2-one
  参考文献：
  名称：

  Harris; Christiansen, Journal of the American Pharmaceutical Association (1912), 1934, vol. 23, p. 108,110

  摘要：

  DOI：
• 作为产物：
  描述：

  3,3-dichloroindolin-2-one 、 邻甲酚 生成 靛红联二甲酚
  参考文献：
  名称：

  Inagaki, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1933, vol. 53, p. 686,696;dtsch.Ref.S.133

  摘要：

  DOI：

文献信息

• Optically active compound and photosensitive resin composition
  申请人：——

  公开号：US20030211421A1

  公开（公告）日：2003-11-13

  A photoactive compound is used in combination with a photosensitizer, represented by the following formula (1): A −[( J ) m −( X-Pro )] n (1) wherein A represents a hydrophobic unit comprising at least one kind of hydrophobic groups selected from a hydrocarbon group and a heterocyclic group, J represents a connecting group, X-Pro represents a hydrophilic group protected by a protective group Pro which is removable by light exposure, m represents 0 or 1, and n represents an integer of not less than 1. The protective group Pro may be removable by light exposure in association with the photosensitizer (especially, a photo acid generator), or may be a hydrophobic protective group. The hydrophilic group may be a hydroxyl group or a carboxyl group. The photoactive compound has high sensitivity to a light source of short wavelength beams, for resist application, therefore, the photoactive compound is advantageously used for forming a pattern with high resolution.

  一种光活性化合物与光敏剂结合使用，由以下公式（1）表示： A −[( J ) m −( X-Pro )] n (1) 其中，A代表至少包括一种从烃基和杂环基中选择的疏水基的疏水单元，J代表连接基团，X-Pro代表由光照可去除的保护基团Pro保护的亲水基团，m代表0或1，n代表不少于1的整数。 保护基团Pro可以与光敏剂（特别是光酸发生剂）一起通过光照可去除，也可以是疏水保护基团。亲水基团可以是羟基或羧基。光活性化合物对短波长光源具有很高的敏感性，用于光刻应用，因此，该光活性化合物有利于形成具有高分辨率的图案。
• [EN] USE OF 4-CYANO-NAPHTHALENE-1, 8-DICARBOXIMIDE DERIVATIVES AND RELATED COMPOUNDS TO PROTECT ORGANIC MATERIAL FROM THE DAMAGING EFFECTS OF LIGHT<br/>[FR] UTILISATION DE DERIVES 4-CYANO-NAPHTHALENE-1, 8-DICARBOXIMIDE ET COMPOSES ASSOCIES POUR LA PROTECTION DE MATIERE ORGANIQUE CONTRE LES EFFETS NUISIBLES DE LA LUMIERE
  申请人：BASF AG

  公开号：WO2005047265A1

  公开（公告）日：2005-05-26

  A description is given of the use of naphthalene-1,8-dicarboxylic monoimides of the formula (I), in which R1 is hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, aryl or heteroaryl and R2 is a radical containing at least one π electron system containing a carbon atom and at least one further atom selected from carbon, oxygen, and nitrogen, with the proviso that the radical contains at least one atom other than carbon; to protect organic material from the damaging effects of light, of compositions which comprise at least one naphthalene-1,8-dicarboxylic monoimide of the formula (I) in an amount which provides protection from the damaging effects of light, and at least one organic material, and of new naphthalene-1,8-dicarboxylic monoimides (I).

  描述了使用式(I)的萘-1,8-二羧酸单亚胺，其中R1是氢、烷基、烯基、环烷基、环烯基、杂环烷基、芳基或杂芳基，R2是一个含有至少一个π电子体系的基团，其中包含一个碳原子和至少一个来自碳、氧和氮的其他原子，但基团至少包含一个碳以外的原子；用于保护有机材料免受光的破坏作用的组合物的描述，该组合物包括至少一种式(I)的萘-1,8-二羧酸单亚胺，其含量提供了对光的破坏作用的保护，以及至少一种有机材料，以及新的萘-1,8-二羧酸单亚胺(I)。
• COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES
  申请人：BASF SE

  公开号：US20160235062A1

  公开（公告）日：2016-08-18

  The invention relates to a copolymer exhibiting both antimicrobial and anti-adhesive properties as well as to a hydrogel. Said hydrogel is obtained from the inventive copolymer and a substrate. Another part of the invention is a process for making the hydrogel, as well as different uses of the inventive copolymer as well as of the hydrogel.

  该发明涉及一种既具有抗菌和抗粘附性能的共聚物，又涉及一种水凝胶。所述水凝胶是由该创新共聚物和基质制得的。该发明的另一部分是制备水凝胶的方法，以及该创新共聚物和水凝胶的不同用途。
• Lambert Salt-Initiated Development of Friedel–Crafts Reaction on Isatin to Access Distinct Derivatives of Oxindoles
  作者：Jabir Khan、Aparna Tyagi、Naveen Yadav、Rina Mahato、Chinmoy K. Hazra

  DOI：10.1021/acs.joc.1c02058

  日期：2021.12.17

  yields. A preliminary mechanistic study revealed that the reaction proceeds via a monoarylated product followed by a nucleophilic attack by another electron-rich arene nucleophile under mild conditions. The potential of newly synthesized symmetric/unsymmetric 3,3-disubstituted oxindole, 3-substituted 3-hydroxy oxindoles, 3,3-di(indolyl)indolin-2-ones, and α-aryl oxindoles as valuable building blocks is

  本文描述了一种温和的无金属且有效的合成生物学上重要的 3-芳基羟吲哚衍生物的途径。使用兰伯特盐引发的靛红加氢芳基化，可以从单一起始底物以良好至优异的收率合成多种单芳基化产物、对称/不对称双芳基化产物和脱氧加氢芳基化产物。初步机理研究表明，反应通过单芳基化产物进行，然后在温和条件下由另一种富电子芳烃亲核试剂进行亲核攻击。进一步说明了新合成的对称/不对称 3,3-二取代羟吲哚、3-取代 3-羟基羟吲哚、3,3-二(吲哚基)吲哚啉-2-酮和 α-芳基羟吲哚作为有价值的结构单元的潜力。
• PURIFICATION OF TRIS-HYDROXYARYL COMPOUNDS
  申请人：Münnich Christian

  公开号：US20110251438A1

  公开（公告）日：2011-10-13

  The present invention is directed to a composition comprising a tris-hydroxyaryl compound having a metal ion impurity content of less than 10 ppm and to a process for the purification of tris-hydroxyaryl compound having a metal ion impurity, comprising at least the following steps: a) conditioning a sulphonic acid group-containing active ion exchanger with a solvent which is suitable for the handling of the tris-hydroxyaryl compounds, b) producing a solution of the tris-hydroxyaryl compounds to be purified in a solvent which is suitable for the handling of the tris-hydroxyaryl compounds, c) contacting the tris-hydroxyaryl compound-containing solution from b) with the conditioned ion exchanger from a), d) separating the tris-hydroxyaryl compound-containing solution from c) from the conditioned ion exchanger, e) removing at least part of the solvent from the solution of the tris-hydroxyaryl compound separated in d) under low temperature stress.

  本发明涉及一种组合物，包括一种三羟基芳基化合物，其金属离子杂质含量低于10 ppm，以及用于纯化具有金属离子杂质的三羟基芳基化合物的方法，包括至少以下步骤：a)用适合处理三羟基芳基化合物的溶剂调节含有磺酸基团的活性离子交换剂，b)在适合处理三羟基芳基化合物的溶剂中制备待纯化的三羟基芳基化合物的溶液，c)将步骤b)中含有三羟基芳基化合物的溶液与步骤a)中的调节离子交换剂接触，d)将步骤c)中含有三羟基芳基化合物的溶液与调节离子交换剂分离，e)在低温应力下从步骤d)中分离的三羟基芳基化合物的溶液中至少去除部分溶剂。