醋酸镍 | 373-02-4

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物 - 羧酸酯及其衍生物的盐
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 醋酸镍
• 中文别名: 乙酸镍(II)盐；乙酸镍
• 英文名称: Acetic acid;nickel
• 英文别名: acetic acid;nickel
• CAS: 373-02-4
• 化学式: C2H4NiO2
• 分子量: 118.75
• InChiKey: XMOKRCSXICGIDD-UHFFFAOYSA-N

物化性质

• 熔点：
  1555°C
• 沸点：
  16.6°C
• 密度：
  1.798 g/cm3
• 稳定性/保质期：
  浅绿色柱状结晶，具有吸湿性。加热至熔点会分解，可溶于水，在100克水中溶解度为16.6克，不溶于乙醇。有毒，应密闭保存。

计算性质

• 辛醇/水分配系数(LogP)：
  0.09
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2915299090

SDS

Name:	Nickel (II) acetate Material Safety Data Sheet
Synonym:	Acetic acid, Nickel (II) salt; Nickelous acetat
CAS:	373-02-4

Section 1 - Chemical Product MSDS Name:Nickel (II) acetate Material Safety Data Sheet
Synonym:Acetic acid, Nickel (II) salt; Nickelous acetat

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
373-02-4	Nickel(ii) acetate		206-761-7

Hazard Symbols: XN
Risk Phrases: 20/22

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation and if swallowed.Carcinogen.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
May cause respiratory tract irritation.
Chronic:
May cause cancer according to animal studies. May cause reproductive and fetal effects.

---

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower lids. Get medical aid immediately.
Skin:
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits, Lower: Not available.
Upper: Not available.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Wash area with soap and water. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

---

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation.
Storage:
Store in a cool, dry place.

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134. Always use a NIOSH-approved respirator when necessary.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Appearance: green
Odor: None reported
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Decomposition Temperature: Not available.
Solubility: Soluble in water.
Specific Gravity/Density: 1.798
Molecular Formula: C4H6O4Ni
Molecular Weight: 176.7296

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
None reported.
Incompatibilities with Other Materials:
None reported.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Has not been reported.

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 373-02-4: QR6125000 LD50/LC50:
CAS# 373-02-4: Oral, mouse: LD50 = 410 mg/kg; Oral, rat: LD50 = 350 mg/kg.
Carcinogenicity:
Nickel(ii) acetate - NTP: Suspect carcinogen OSHA: Possible Select carcinogen See actual entry in RTECS for complete information.

---

Section 12 - ECOLOGICAL INFORMATION
For further information, contact Fisher Scientific.

---

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

---

Section 14 - TRANSPORT INFORMATION

CDG/CPL
IMO
No information available.
IATA
No information available.
RID/ADR
No information available.
Canadian TDG
No information available.

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/22 Harmful by inhalation and if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 373-02-4:
Canada
CAS# 373-02-4 is listed on Canada's DSL/NDSL List.
WHMIS: Not available.
CAS# 373-02-4 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 373-02-4 is listed on the TSCA inventory.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

应用

醋酸镍在有机化学中常用作金属催化剂，商业化的醋酸镍往往是其水合物，可用于催化偶联反应、还原反应等，在金属有机反应、镀镍、金属着色以及药物分子制备中有着较为广泛的应用。

制备

1. 向金属镍粉中加入盐酸和氯化铜溶液或硫酸和硫酸铜溶液进行反应，经除杂、蒸发得到镍盐。
2. 将步骤1所得的镍盐与NaOH溶液充分反应，过滤后得到Ni(OH)₂。
3. 将步骤2中得到的Ni(OH)₂用醋酸酸化，经过蒸发、结晶得到醋酸镍产品。所使用的酸和铜盐溶液可以为盐酸和氯化铜溶液或硫酸和硫酸铜溶液；所得镍盐可以是氯化镍或硫酸镍。

用途

该物质可用于媒染剂和电镀等领域。

化学性质

纯品为绿色单斜晶系柱状结晶，商品多为22%～32%可湿性粉剂。外观呈绿色结晶或结晶状粉末，微有醋酸味，溶于水或醇。