醋酸锰(3+) | 993-02-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 醋酸锰(3+)
• 中文别名: 醋酸锰(Ⅲ)
• 英文名称: Mangantriacetat
• 英文别名: Manganese(III) acetate；manganese(3+);triacetate
• CAS: 993-02-2
• 化学式: C₆H₉MnO₆
• 分子量: 232.072
• InChiKey: AHSBSUVHXDIAEY-UHFFFAOYSA-K

物化性质

• 稳定性/保质期：
  棕色粉末状结晶，易水解，在冷水中也会迅速水解。应密封保存以防水解。

计算性质

• 辛醇/水分配系数(LogP)：
  -3.73
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  120
• 氢给体数：
  0
• 氢受体数：
  6

SDS

Name:	Manganese(III) acetate dihydrate 98% Material Safety Data Sheet
Synonym:	Acetic acid, manganese(3+) salt, dihydrate; Manganese triacetate dihydrate
CAS:	993-02-2

Section 1 - Chemical Product MSDS Name:Manganese(III) acetate dihydrate 98% Material Safety Data Sheet
Synonym:Acetic acid, manganese(3+) salt, dihydrate; Manganese triacetate dihydrate

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
993-02-2	Manganese(III) acetate dihydrate	98	unlisted

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Effects may be delayed.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Use with adequate ventilation. Avoid breathing dust.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 993-02-2: United States OSHA: 5 mg/m3 Ceiling (as Mn) (listed under Mangan compounds, n.o.s.).
Belgium - TWA: (listed as manganese compounds, n.o.s.): 0.2 mg/m3 (as Mn) Japan: (listed as manganese compounds, n.o.s.): 0.3 mg/m3 OEL (ex organic compounds, as Mn) Netherlands: (listed as manganese compounds, n.o.s.): 3 mg/m3 STE (as Mn) Netherlands: (listed as manganese compounds, n.o.s.): 1 mg/m3 MAC Mn) CAS# 19513-05-4: United States OSHA: 5 mg/m3 Ceiling (as Mn) (listed under Mangan compounds, n.o.s.).
Belgium - TWA: (listed as manganese compounds, n.o.s.): 0.2 mg/m3 (as Mn) Japan: (listed as manganese compounds, n.o.s.): 0.3 mg/m3 OEL (ex organic compounds, as Mn) Netherlands: (listed as manganese compounds, n.o.s.): 3 mg/m3 STE (as Mn) Netherlands: (listed as manganese compounds, n.o.s.): 1 mg/m3 MAC Mn) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder and chunks
Color: brown - orange-brown
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C6H9O6Mn.2H2O
Molecular Weight: 268.09

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong reducing agents, finely powdered metals, strong acids, strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, oxides of manganese.
Hazardous Polymerization: Has not been reported.

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 993-02-2 unlisted.
CAS# 19513-05-4 unlisted.
LD50/LC50:
Not available.
Not available.
Carcinogenicity:
Manganese(3+) acetate - Not listed by ACGIH, IARC, or NTP.
Manganese(III) acetate dihydrate - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 993-02-2: No information available.
CAS# 19513-05-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 993-02-2 is not listed on Canada's Ingredient Disclosure List.
CAS# 19513-05-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 993-02-2 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 19513-05-4 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

制备方法

1. 在充分搅拌下，将20克六水硝酸锰(Ⅱ)[Mn(NO3)2·6H2O]分批加入80克醋酸酐中，并稍微加热后，会发生激烈的放热反应，并有大量气体放出。反应结束后，冷却，析出固体。抽滤，先用少量醋酸酐洗涤，再用乙醚洗涤至无醋酸气味。收率80%。

2. 500毫升乙酸和48克乙酸锰(I)四水合物回流20分钟后，在保持微微回流的条件下，慢慢加入8.0克高锰酸钾。再回流30分钟后，将混合物冷至室温。加85毫升水，较多的水量会改变乙酸锰(I)的产率及下一步反应的产率。加入少量乙酸锰(Ⅰ)作晶种，16小时后滤出乙酸锰(Ⅰ)，用冷乙酸洗涤几次，在空气中干燥。在含1水的醋酸中重结晶。碘量法测定其纯度＞98%。

为了得到活性最高的乙酸锰(Ⅰ)作为下一步反应的起始物质，必须加入相当于水合物中所含水量的乙酸酐。乙酸锰(Ⅰ)也可现用现制。

合成制备方法

1. 在充分搅拌下，将20克六水硝酸锰(Ⅱ)[Mn(NO3)2·6H2O]分批加入80克醋酸酐中，并稍微加热后，会发生激烈的放热反应，并有大量气体放出。反应结束后，冷却，析出固体。抽滤，先用少量醋酸酐洗涤，再用乙醚洗涤至无醋酸气味。收率80%。

2. 500毫升乙酸和48克乙酸锰(I)四水合物回流20分钟后，在保持微微回流的条件下，慢慢加入8.0克高锰酸钾。再回流30分钟后，将混合物冷至室温。加85毫升水，较多的水量会改变乙酸锰(I)的产率及下一步反应的产率。加入少量乙酸锰(Ⅰ)作晶种，16小时后滤出乙酸锰(Ⅰ)，用冷乙酸洗涤几次，在空气中干燥。在含1水的醋酸中重结晶。碘量法测定其纯度＞98%。

为了得到活性最高的乙酸锰(Ⅰ)作为下一步反应的起始物质，必须加入相当于水合物中所含水量的乙酸酐。乙酸锰(Ⅰ)也可现用现制。

反应信息

• 作为反应物：
  描述：

  醋酸锰(3+) 以4%的产率得到
  参考文献：
  名称：

  NISHINO, HIROSHI;KUROSAWA, KAZU, BULL. CHEM. SOC. JAP., 1983, 56, N 6, 1682-1687

  摘要：

  DOI：
• 作为产物：
  描述：

  potassium permanganate 、 manganese(II) acetate 、 溶剂黄146 生成 醋酸锰(3+)
  参考文献：
  名称：

  PASTOR, TIBOR J.;ANTONIJEVIC, VOJKA V., MIKROCHIM. ACTA , 1,(1990) N-6, C. 313-319

  摘要：

  DOI：
• 作为试剂：
  描述：

  t-butyl 2-methyl-4-(1-trifluoromethylethenyl)carbanilate 、 苯甲酰乙腈 在 醋酸锰(3+) 水 、 乙酸乙酯 、 Sodium sulfate-III 、 silica gel 、 ethyl acetate n-hexane 作用下， 以 溶剂黄146 为溶剂， 反应 2.0h， 以to obtain 0.35 g of the objective material as pale yellowish crystals的产率得到t-Butyl 4-(3-cyano-2-phenyl-5-trifluoromethyl-4,5-dihydrofuran-5-yl)-2-methylcarbanilate
  参考文献：
  名称：

  Substituted benzanilide compound and noxious organism controlling agent

  摘要：

  本发明提供了一种新型农药化学品，特别是一种杀虫剂或螨虫剂，涉及一种由式(1)表示的取代苯甲酰胺化合物：其中G代表环，例如G-7、G-13和G-71等，W1和W2分别独立地表示氧原子或硫原子，X表示卤素原子等，Y表示C1到C6烷基等，R1、R2和R3分别独立地表示氢原子、C1到C12烷基或C1到C6烷基硫（C1到C6）烷基等，R4、R5、R6a和R6b分别独立地表示氢原子、C1到C6烷基、C1到C6卤代烷基或苯基，该苯基可以被（Z2）p1等取代，R6i、R6j和R6k分别独立地表示氢原子或卤素原子等，Z2表示卤素原子、C1到C6卤代氧基或C1到C6烷基磺酰基等，m和n分别独立地表示0到4的整数，p1表示1到5的整数，或其盐，以及含有这些的有害生物控制剂。

  公开号：

  US20050250822A1

文献信息

• Reactions of Alkylarenes, Benzyl Alcohols, Sulfides, and Phosphine with Manganese(III) Acetate–Chloride Ions
  作者：Yasuo Futami、Hiroshi Nishino、Kazu Kurosawa

  DOI：10.1246/bcsj.62.3567

  日期：1989.11

  The reactions of methoxytoluenes and methylnaphthalenes with a manganese(III) acetate–Cl− complex gave the corresponding aldehydes in 8 to 54% yields. In a similar reaction aromatic compounds having a methylene group were oxidized to the corresponding acetates and ketones. The primary and secondary benzyl alcohols gave aldehydes and ketones, respectively, in good yields. Sulfides and phosphine were

  甲氧基甲苯和甲基萘与乙酸锰 (III)-Cl− 络合物的反应以 8% 到 54% 的产率得到相应的醛。在类似的反应中，具有亚甲基的芳族化合物被氧化成相应的乙酸酯和酮。伯和仲苯甲醇分别以良好的产率得到醛和酮。硫化物和膦被络合物氧化成氧化物。具有较低电离电位的烷基芳烃的反应可以用涉及乙酸锰（III）-Cl-配合物的电子转移机制来解释。
• Reactions of 1,1-Disubstituted Alkenes with Acetoacetamides and Molecular Oxygen in the Presence of Manganese(III) Acetate
  作者：Chang-Yi Qian、Hiroshi Nishino、Kazu Kurosawa

  DOI：10.1246/bcsj.64.3557

  日期：1991.12

  The reactions of 1,1-disubstituted ethenes with acetoacetamide or N-substituted acetoacetamides, and molecular oxygen in the presence of manganese(III) acetate gave a mixture of c-4- and t-4-carbamoyl-3-methyl-1,2-dioxan-r-3-ols in good yields. Effects of substituents in the alkenes as well as in the carbamoyl group in the acetoacetamides were observed. Stereochemistry and the reactivity of the 4-

  1,1-二取代的乙烯与乙酰乙酰胺或 N-取代的乙酰乙酰胺以及分子氧在乙酸锰 (III) 存在下反应得到 c-4- 和 t-4-氨基甲酰基-3-甲基-1 的混合物， 2-二恶烷-r-3-醇收率良好。观察到烯烃中的取代基以及乙酰乙酰胺中的氨基甲酰基中的取代基的影响。讨论了 4-carbamoyl-3-methyl-1,2-dioxan-3-ols 的立体化学和反应性。
• Reduction and oxidation of carbon-carbon double bonds of 1,1,4,4-tetrakis(trimethylsilyl)butatriene
  作者：Tetsuo Kusumoto、Tamejiro Hiyama

  DOI：10.1016/s0040-4039(00)95428-5

  日期：1987.1

  Hydrogenation, hydrosilylation and oxidation of the title butatriene was found to take place at C(1)C(2) double bond exclusively.

  标题丁二烯的氢化，氢化硅烷化和氧化被发现仅在C（1）C（2）双键处发生。
• Potassium permanganate-mediated radical reactions: chemoselective addition of acetone to olefins
  作者：Ursula Linker、Berthold Kersten、Torsten Linker

  DOI：10.1016/0040-4020(95)00563-n

  日期：1995.1

  efficient protocol for the radical addition of acetone (1) to olefins 2a-d, mediated by potassium permanganate, has been developed. The in situ generation of manganese(III) allows the chemoselective synthesis of saturated C-C bond formation products 4a-d in 39–58% yield. Furthermore, the required amount of manganese is reduced drastically in account of the catalytic reaction cycle.

  已经开发了一种实用且有效的方案，用于将丙酮（1）自由基加成到高锰酸钾介导的烯烃2a-d中。该原位生成的锰（III）允许饱和CC键形成产物的化学选择性合成图4a-d中39-58％的产率。此外，由于催化反应循环，大大减少了所需的锰量。
• Reactions of α,β-Unsaturated Carboxylates, Malonates and Phenylacetates with Manganese(III) Acetate in the Presence of Chloride Ions
  作者：Hiroshi Yonemura、Hiroshi Nishino、Kazu Kurosawa

  DOI：10.1246/bcsj.60.809

  日期：1987.2

  The reaction of alkyl (E)-3-phenylpropenoates with manganese(III) acetate in the presence of Cl− ions gave alkyl (Z)-2-chloro-3-phenylpropenoates and alkyl 2,3-dichloro-3-phenylpropanoates. Ethyl (E)-2,3-diphenylpropenoate yielded ethyl 2,3-dichloro-2,3-diphenylpropanoate. Alkyl 3,3-diphenylpropenoates gave mainly alkyl 2-chloro-3,3-diphenyl-propenoates. Ethyl 1-cyclohexenecarboxylate gave ethyl 1

  (E)-3-苯基丙烯酸烷基酯与乙酸锰(III)在Cl-离子存在下的反应产生(Z)-2-氯-3-苯基丙烯酸烷基酯和2,3-二氯-3-苯基丙酸烷基酯。(E)-2,3-二苯基丙烯酸乙酯产生2,3-二氯-2,3-二苯基丙酸乙酯。3,3-二苯基丙烯酸烷基酯主要产生2-氯-3,3-二苯基-丙烯酸烷基酯。1-环己烯羧酸乙酯得到1,2-二氯环己烷羧酸乙酯。丙二酸二甲酯产生二氯丙二酸二甲酯和1,2-二氯-1,1,2,2-乙四甲酸四甲酯。取代的丙二酸酯产生α-氯衍生物。苯乙酸甲酯生成α-乙酰氧基衍生物。