(3-吡咯)-4-丁酸 | 30000-61-4

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 中文名称: (3-吡咯)-4-丁酸
• 中文别名: 4-(3-吡咯基)丁酸
• 英文名称: 1H-pyrrole-3-butyric acid
• 英文别名: 4-(3-pyrrolyl)butyric acid；4-(3-pyrrolyl)butanoic acid；4--buttersaeure；Pyrrole-3-butyric acid；4-(1H-pyrrol-3-yl)butanoic acid
• CAS: 30000-61-4
• 化学式: C₈H₁₁NO₂
• mdl: MFCD07438025
• 分子量: 153.181
• InChiKey: ZILGRACWFSKIFU-UHFFFAOYSA-N

物化性质

• 熔点：
  91-95 °C

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.375
• 拓扑面积：
  53.1
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36/37
• 危险类别码：
  R36/37/38
• 海关编码：
  2933990090
• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  (3-吡咯)-4-丁酸 在 对苯二酚 作用下， 以 丙酸 、 苯 为溶剂， 反应 0.5h， 生成 4-((4Z,10Z,15Z,19Z)-5,10,15,20-Tetra-p-tolyl-22,24-dihydro-porphin-2-yl)-butyric acid; compound with triethyl-amine
  参考文献：
  名称：

  Vinyl Polymers Bearing a Pyrrole Ring. II. 5,10,15,20-Tetraphenylporphyrins with a Substituent-Bearing Vinyl Group at the Pyrrole Residue and Their Zinc Complexes

  摘要：

  合成了5,10,15,20-四苯基卟啉（Por），其在吡咯残基上附有带有苯乙烯双键的取代基，并使用酰胺或酯作为间隔链，起始材料为3取代吡咯。由Por制备的锌卟啉（ZnPor）与1-乙烯基-2-吡咯烷酮的自由基共聚合反应结果优于单独使用Por。

  DOI：

  10.1246/bcsj.64.2300
• 作为产物：
  描述：

  4-氧-4-[1-(苯磺酰基)-1H-吡咯-3-基]丁酸 在 盐酸 、 sodium hydroxide 、 amalgamated zinc 作用下， 以 甲醇 、 水 、 甲苯 为溶剂， 反应 25.0h， 生成 (3-吡咯)-4-丁酸
  参考文献：
  名称：

  Strategies towards functionalised electronically conducting organic copolymers: Part 2. Copolymerisation

  摘要：

  Here we discuss the application of X-ray photoelectron spectroscopy and absorbance-reflectance FT-IR spectroscopy to establish and quantify reactivity relationships between a range of thiophene and pyrrole monomers. In particular we investigate the application of these techniques to the characterisation of conducting polymer materials grown potentiostatically from solutions containing a binary mixture of monomers. Our data have shown that XPS is especially effective in determining polymer composition and the linear correlation between this and solution composition has enabled prescriptive synthesis of copolymer materials from the different combinations of monomers described here. This technique is much more convenient and more reliable than elemental analysis. In contrast we show that FT-IR studies, whilst providing a useful qualitative guide to the functional group content of the material, do not facilitate detailed quantitative analysis because of large intrinsic errors.

  DOI：

  10.1039/b001279n

文献信息

• Vinyl Polymers Bearing Pyrrole Ring: I. Syntheses of Pyrroles Having 3-Substituent Bearing Vinyl Group
  作者：Hiroyoshi Kamogawa、Takuharu Nakata、Shin Ohori、Sei Komatsu

  DOI：10.1246/bcsj.64.1066

  日期：1991.3

  Pyrroles having 3-substituent bearing the vinyl group with an ester or amide spacer were synthesized starting with 1-(phenylsulfonyl)pyrrole. Homopolymerization of the vinyl monomers thus synthesized provided cross-linked insoluble polymers, but their copolymers with 1-vinyl-2-pyrrolidone were soluble in common solvents.

  以 1-(苯基磺酰基)吡咯为起始原料合成带有带有酯或酰胺间隔基团的乙烯基的 3-取代基的吡咯。如此合成的乙烯基单体的均聚提供了交联的不溶性聚合物，但它们与 1-乙烯基-2-吡咯烷酮的共聚物可溶于普通溶剂。
• PROCESS FOR PREPARING A POLYMER-COATED TEXTILE HAVING OMNIPHOBIC PROPERTIES
  申请人：Université Côte d'Azur

  公开号：EP4098798A1

  公开（公告）日：2022-12-07

  The present invention relates to a process for preparing a textile coated with a conducting polymer functionalized with fluorinated chains. It also relates to a polymer-coated textile obtainable by such a process.

  本发明涉及一种制备涂有氟化链功能化导电聚合物的纺织品的工艺。本发明还涉及一种可通过该工艺获得的聚合物涂层织物。
• Methods and apparatus for quantification of nucleic acid amplification by monitoring impedances
  申请人：Aydemir Nihan

  公开号：US10167501B2

  公开（公告）日：2019-01-01

  The present invention relates to methods and apparatuses for amplifying, detecting, and optionally quantifying, nucleic acids. In one aspect the method comprises (a) providing a reaction volume comprising (i) a first electrode comprising an electrochemically-active conducting polymer, a first single-stranded nucleic acid molecule capable of hybridizing to a target nucleic acid, wherein the first nucleic acid molecule is covalently attached to the electrochemically-active conducting polymer, and (ii) a second electrode, (b) providing a reaction mixture to the reaction volume, the reaction mixture comprising a target nucleic acid, a nucleic acid polymerase, a redox couple, and nucleic acid amplification reagents, (c) amplifying the nucleic acid, and (d) measuring the impedance of the first electrode at least once during the nucleic acid amplification reaction.

  本发明涉及用于扩增、检测和可选量化核酸的方法和装置。在一个方面，该方法包括：(a) 提供一个反应容积，该反应容积包括(i) 第一电极，该第一电极包含电化学活性导电聚合物、能够与目标核酸杂交的第一单链核酸分子，其中第一核酸分子共价连接到电化学活性导电聚合物上；(ii) 第二电极；(b) 向反应容积提供反应混合物，该反应混合物能够与目标核酸杂交，其中第一核酸分子共价连接到电化学活性导电聚合物上、和 (ii) 第二电极，(b) 向反应容积提供反应混合物，反应混合物包括目标核酸、核酸聚合酶、氧化还原偶联剂和核酸扩增试剂，(c) 扩增核酸，和 (d) 在核酸扩增反应期间至少测量一次第一电极的阻抗。
• Systems, structures and materials for electrochemical device thermal management
  申请人：Global Web Horizons, LLC

  公开号：US10431858B2

  公开（公告）日：2019-10-01

  This disclosure provides casings and materials for the thermal management and protection of an electrochemical cell. The casing may also comprise a composite polymeric material for electrochemical cell thermal management, the composite polymeric material comprising a crosslinked polyether polyol phase change material configured to be in physical contact with at least a portion of an electrochemical cell.

  本公开提供了用于电化学电池热管理和保护的外壳和材料。外壳还可包括用于电化学电池热管理的复合聚合材料，复合聚合材料包括交联聚醚多元醇相变材料，该材料被配置为与电化学电池的至少一部分进行物理接触。
• Hetero functional binding systems
  申请人：Anteo Technologies Pty Ltd

  公开号：US10768176B2

  公开（公告）日：2020-09-08

  The present invention relates to reagents and methods for binding compounds to surfaces that are hydrophobic. More specifically, the invention relates to simple methods for coating of hydrophobic planar, membrane or particle surfaces to facilitate binding of molecules such as labels, dyes, synthetic and biological polymers and/or nanoparticles thereto.

  本发明涉及将化合物与疏水性表面结合的试剂和方法。更具体地说，本发明涉及涂覆疏水性平面、膜或颗粒表面以促进标签、染料、合成和生物聚合物和/或纳米颗粒等分子与之结合的简单方法。