2,5-Dichloro-3-[9-hydroxy-8-(2-methylphenyl)-5-oxo-6,10-dipyridin-3-ylbenzo[a]xanthen-12-yl]terephthalic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 2,5-Dichloro-3-[9-hydroxy-8-(2-methylphenyl)-5-oxo-6,10-dipyridin-3-ylbenzo[a]xanthen-12-yl]terephthalic acid
• 化学式: C₄₂H₂₄Cl₂N₂O₇
• 分子量: 739.5
• InChiKey: QYLPDUNKHUQAOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  53
• 可旋转键数：
  6
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.02
• 拓扑面积：
  147
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS
  申请人：Lee G. Linda

  公开号：US20070254298A1

  公开（公告）日：2007-11-01

  Atropisomeric energy-transfer dye compounds are disclosed. A variety of molecular biology applications utilize atropisomeric xanthene fluorescent dyes as labels for substrates such as nucleotides, nucleosides, polynucleotides, polypeptides and carbohydrates. Methods include DNA sequencing, DNA fragment analysis, PCR, SNP analysis, oligonucleotide ligation, amplification, minisequencing, and primer extension.