3-[4-(1,3-Benzodioxol-5-ylmethylamino)phenyl]-7-hydroxychromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 3-[4-(1,3-Benzodioxol-5-ylmethylamino)phenyl]-7-hydroxychromen-4-one
• 化学式: C₂₃H₁₇NO₅
• 分子量: 387.4
• InChiKey: BAWHGFUOTWMUPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  77
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• [EN] ANTIGIARDIAL AGENTS AND USE THEREOF<br/>[FR] AGENTS ANTI-GIARDIASE ET LEUR UTILISATION
  申请人：UNIV MISSISSIPPI

  公开号：WO2004014886A1

  公开（公告）日：2004-02-19

  The present invention provides a method of preventing or treating one or more of the following medical conditions, or treating symptoms of one or more of the following medical conditions: amebic infections, giardiasis, estrogen deficient states, osteoporosis, cardiovascular heart disease, high cholesterol levels, hyperlipidemia, cancer by administering to a subject having, or predisposed to, one or more of the conditions, a therapeutically effective amount of a compound of the present invention and a pharmaceutically acceptable carrier.

  本发明提供了一种预防或治疗以下一种或多种医疗状况，或治疗以下一种或多种医疗状况的症状的方法：阿米巴感染、贾第虫病、雌激素缺乏状态、骨质疏松症、心血管疾病、高胆固醇水平、高脂血症、癌症，通过向具有或易于患上一种或多种这些疾病的受试者施用本发明化合物的治疗有效量和药学上可接受的载体。
• Antigiardial agents and use thereof
  申请人：Avery Mitchell

  公开号：US20060106091A1

  公开（公告）日：2006-05-18

  The present invention provides a method of preventing or treating one or more of the following medical conditions, or treating symptoms of one or more of the following medical conditions: amebic infections, giardiasis, estrogen deficient states, osteoporosis, cardiovascular heart disease, high cholesterol levels, hyperlipidemia, cancer by administering to a subject having, or predisposed to, one or more of the conditions, a therapeutically effective amount of a compound of the present invention and a pharmaceutically acceptable carrier.

  本发明提供了一种预防或治疗下列一种或多种病症，或治疗下列一种或多种病症的症状的方法：阿米巴感染、贾第鞭毛虫病、雌激素缺乏状态、骨质疏松症、心血管心脏病、高胆固醇水平、高脂血症、癌症，其方法是向患有或易患上述一种或多种病症的受试者施用治疗有效量的本发明化合物和药学上可接受的载体。
• Novel Antigiardial Agents and Methods of Use Thereof
  申请人：Avery Mitchell

  公开号：US20090192152A1

  公开（公告）日：2009-07-30

  The present invention provides a method of preventing or treating one or more of the following medical conditions, or treating symptoms of one or more of the following medical conditions: amebic infections, giardiasis, estrogen deficient states, osteoporosis, cardiovascular heart disease, high cholesterol levels, hyperlipidemia, cancer by administering to a subject having, or predisposed to, one or more of the conditions, a therapeutically effective amount of a compound of the present invention and a pharmaceutically acceptable carrier.
• US7468445B2
  申请人：——

  公开号：US7468445B2

  公开（公告）日：2008-12-23