8-Chloro-6,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 8-Chloro-6,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
• 化学式: C₁₅H₉ClO₅
• 分子量: 304.68
• InChiKey: RTWODMZKQPPPDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• 6-Hydroxy isoflavones derivatives and medicaments involving same
  申请人：Kelly Edmund Graham

  公开号：US20050049424A1

  公开（公告）日：2005-03-03

  Isoflavone compounds of the formula (I) or (II) Where R can be R 7? or OR 7? or O and the formula (III) is either a single or double bond extends to Y then Y is an optionally substituted benzyl. W, R 1?, Z o? R 2? and R 7? are as defined in the specification. The compounds are useful for the treatment of certain diseases and disorders, including cancer and inflammation.

  式 (I) 或 (II) 的异黄酮化合物 其中 R 可以是 R 7.或 OR 7? 或 O，且式（III）中的单键或双键延伸至 Y，则 Y 为任选取代的苄基。W、R 1?, Z o?R 2.和 R 7? 如说明书中所定义。这些化合物可用于治疗某些疾病和失调，包括癌症和炎症。
• 6-HYDROXY ISOFLAVONES, DERIVATIVES AND MEDICAMENTS INVOLVING SAME
  申请人：Novogen Research Pty. Ltd.

  公开号：EP1448542A1

  公开（公告）日：2004-08-25
• EP1448542A4
  申请人：——

  公开号：EP1448542A4

  公开（公告）日：2005-11-16
• [EN] 6-HYDROXY ISOFLAVONES, DERIVATIVES AND MEDICAMENTS INVOLVING SAME<br/>[FR] 6-HYDROXY ISOFLAVONES, DERIVES ET MEDICAMENTS LES METTANT EN OEUVRE
  申请人：NOVOGEN RES PTY LTD

  公开号：WO2003035635A1

  公开（公告）日：2003-05-01

  Isoflavone compounds of the formula (I) or (II) Where R can be R7 or OR7 or O and the formula (III) is either a single or double bond extends to Y then Y is an optionally substituted benzyl. W, R1, Zo R2 and R7 are as defined in the specification. The compounds are useful for the treatment of certain diseases and disorders, including cancer and inflammation.