2-Heptyl-decansaeure | 53705-90-1

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Heptyl-decansaeure
• 英文别名: Hexadecan-8-carbonsaeure；2-heptyl-decanoic acid；2-Heptyldecanoic acid
• CAS: 53705-90-1
• 化学式: C₁₇H₃₄O₂
• 分子量: 270.456
• InChiKey: UWORJOUXMWXRPU-UHFFFAOYSA-N

物化性质

• 沸点：
  386.1±10.0 °C(Predicted)
• 密度：
  0.889±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险性防范说明：
  P261,P264,P271,P280,P302+P352,P304+P340,P305+P351+P338,P312,P332+P313,P337+P313,P362,P403+P233,P405,P501
• 危险性描述：
  H315,H319,H335

反应信息

• 作为反应物：
  描述：

  2-Heptyl-decansaeure 在 4-二甲氨基吡啶 、 sodium hypochlorite 、 2,2,6,6-四甲基哌啶氧化物 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 potassium bromide 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 16.0h， 生成 6-Oxohexyl 2-heptyldecanoate
  参考文献：
  名称：

  一种阳离子脂质、含该阳离子脂质的脂质体、含该脂质体的核酸药物组合物及其制剂和应用

  摘要：

  本发明提供了一种结构如通式(1)所示的新型阳离子脂质，具体涉及一种氮支化的阳离子脂质，还涉及包含该阳离子脂质的脂质体、含该阳离子脂质的脂质体核酸药物组合物及其制剂和应用，式中各符号的定义如本文所定义的。本发明涉及的一种包含式(1)所示的阳离子脂质的阳离子脂质体，能够提高核酸药物的装载率和转运率。本发明涉及的一种前述阳离子脂质体核酸药物组合物制剂有很好的细胞相容性和较高的基因转染力，能提高核酸药物的治疗和/或预防疗效。

  公开号：

  CN113402405B
• 作为产物：
  描述：

  2-庚基丙二酸二乙酯 160.0~180.0 ℃ 、2.67 kPa 条件下， 生成 2-Heptyl-decansaeure
  参考文献：
  名称：

  Asinger,F.; Scheuffler,B., Journal fur praktische Chemie (Leipzig 1954), 1960, vol. 10, p. 265 - 289

  摘要：

  DOI：

文献信息

• Concentrated, stable, translucent or clear, fabric softening compositions including chelants
  申请人：Wahl Hoffman Errol

  公开号：US20050202998A1

  公开（公告）日：2005-09-15

  Clear or translucent fabric softening compositions having a biodegradable fabric softening active and an added chelating agent are disclosed. The biodegradable fabric softening active preferably has the formula: wherein each R substituent is hydrogen or a short chain C 1 -C 6 , preferably C 1 -C 3 alkyl or hydroxyalkyl group, e.g., methyl (most preferred), ethyl, propyl, hydroxyethyl, and the like, benzyl, or mixtures thereof; each m is 2 or 3; each n is from 1 to about 4, preferably 2; each Y is —O—(O)C—, —(R)N—(O)C—, —C(O)—N(R)—, or —C(O)—O—, preferably —O—(O)C—; the sum of carbons in each R 1 , plus one when Y is —O—(O)C— or —(R)N—(O)—, is C 6 -C 22 , preferably C 12-22 , more preferably C 14 -C 20 , but no more than one R 1 or YR 1 sum being less than about 12 and then the other R 1 or YR 1 sum is at least about 16, with each R 1 being a long chain C 5 -C 21 (or C 6 -C 22 ), preferably C 9 -C 19 (or C 9 -C 20 ), most preferably C 11 -C 17 (or C 12 -C 18 ), straight, branched, unsaturated or polyunsatruated alkyl, the average Iodine Value of the parent fatty acid of the R 1 being from about 20 to about 140. The chelating agent is preferably diaminetriaminepentaacetic acid. The compositions display excellant clarity with a percentage haze in the transmission mode of a Hunter Color analysis of less than 90%, preferably less than 50%.

  本文揭示了具有可生物降解织物柔软活性剂和添加螯合剂的透明或半透明织物柔软组合物。可生物降解织物柔软活性剂优选具有以下公式： 其中，每个R取代基是氢或短链C1-C6，优选是C1-C3烷基或羟基烷基，例如，甲基（最优选），乙基，丙基，羟乙基等，苯甲基或其混合物；每个m为2或3；每个n为1至约4，优选为2；每个Y为—O—（O）C—，—（R）N—（O）C—，—C（O）—N（R）—或—C（O）—O—，优选为—O—（O）C—；当Y为—O—（O）C—或—（R）N—（O）—时，每个R1中碳的总数加一为C6-C22，优选为C12-22，更优选为C14-C20，但不超过一个R1或YR1总和小于约12，然后另一个R1或YR1总和至少约为16，每个R1为长链C5-C21（或C6-C22），优选为C9-C19（或C9-C20），最优选为C11-C17（或C12-C18），直链、支链、不饱和或多不饱和烷基，R1的父脂肪酸的平均碘值约为20至约140。螯合剂优选为二氨基三乙酸五钠盐。该组合物在Hunter Color分析的透射模式下具有出色的清晰度，其百分之雾度小于90％，优选小于50％。
• COSMETIC PREPARATION, METHOD FOR PRODUCING SAME, COMPOSITION FOR COSMETIC PREPARATIONS, COSMETIC PREPARATION CONTAINING THE COMPOSITION FOR COSMETIC PREPARATIONS AND METHOD FOR PRODUCING SAME, AND CLEANSER FOR INDUSTRIAL USE
  申请人：Kobayashi Tatsuya

  公开号：US20110306665A1

  公开（公告）日：2011-12-15

  The present invention is related to: (1) a cosmetic preparation including an emulsifying agent, 1,3-propanediol (PDO), and a PDO difatty acid ester, wherein the fatty acids constituting the PDO difatty acid ester are one or two or more types of fatty acids selected from isostearic acid, n-octanoic acid, and n-decanoic acid, and a method for producing the cosmetic preparation; (2) a composition for cosmetic preparations, which includes the PDO difatty acid ester, a cosmetic preparation including the composition for cosmetic preparations, and a method for producing the cosmetic preparation; and (3) a cleanser for industrial use, which includes a PDO difatty acid ester that has fatty acid residues of n-octanoic acid and n-decanoic acid. The present invention is able to provide: a cosmetic preparation, a composition for cosmetic preparations, and a cosmetic preparation including the composition for cosmetic preparations, which have excellent cleansing properties, low irritation properties, moisturizing properties, and feeling of use, with reduced load on the environment; methods for producing the same; and, in addition, a cleanser for industrial use which has excellent cleansing properties and low corrosion properties, with reduced load on the environment.

  本发明涉及以下内容：（1）一种化妆品制剂，包括乳化剂、1,3-丙二醇（PDO）和PDO双脂肪酸酯，其中构成PDO双脂肪酸酯的脂肪酸是从异硬脂酸、正辛酸和正癸酸中选择的一种或两种或更多种类型的脂肪酸，并提供一种制备该化妆品制剂的方法；（2）一种用于化妆品制剂的组合物，包括PDO双脂肪酸酯，以及包括该组合物的化妆品制剂和制备该化妆品制剂的方法；（3）一种用于工业清洁的清洁剂，其中包括具有正辛酸和正癸酸脂肪酸残基的PDO双脂肪酸酯。本发明能够提供具有卓越的清洁性能、低刺激性、保湿性和使用感觉，并减少对环境的负荷的化妆品制剂、用于化妆品制剂的组合物以及包括该组合物的化妆品制剂，以及制备它们的方法；此外，还提供一种具有卓越的清洁性能和低腐蚀性，并减少对环境的负荷的工业清洁剂。
• CATIONIC LIPID
  申请人：Kuboyama Takeshi

  公开号：US20130129811A1

  公开（公告）日：2013-05-23

  The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I) (wherein: R 1 and R 2 are, the same or different, each (Z)-pentadecenyl, (Z)-hexadecenyl or (Z)-heptadecenyl, etc, a and b are, the same or different, each 0 to 3, m is 1, the dotted line is a single bond or absent, X 1 and X 2 are hydrogen atoms, or are combined together to form a single bond or alkylene, X 4 is absent or is alkylene, etc X 3 is absent or is alkyl, etc, Y is absent or anion, L 3 is a single bond, —CO—O— or —O—CO— R 3 is hydrogen atoms, alkyl, etc, L 1 and L 2 are —O—, —CO—O— or —O—CO—) and the like.

  本发明提供一种阳离子脂质，可以使核酸轻松地进入细胞，其化学式为（I）（其中：R1和R2相同或不同，分别为（Z）-十五碳烯基，（Z）-十六碳烯基或（Z）-十七碳烯基等；a和b相同或不同，均为0至3；m为1；虚线为单键或不存在；X1和X2为氢原子，或结合在一起形成单键或烷基；X4不存在或为烷基等；X3不存在或为烷基等；Y不存在或为阴离子；L3为单键，-CO-O-或-O-CO-；R3为氢原子，烷基等；L1和L2为-O-，-CO-O-或-O-CO-等）。
• Chemical composition for external application
  申请人：Sansho Seiyaku Co., Ltd.

  公开号：EP0381057A2

  公开（公告）日：1990-08-08

  Disclosed is a chemical composition for external application, which comprises a kojic acid or kojic acid derivative and an unsaturated linear fatty acid having from 4 to 26 carbon atoms and having from 1 to 6 unsaturated bonds where the position(s) of the unsaturated bond(s) is (are) any desired position(s) in the alkyl chain of the acid except the terminal opposite to the carboxyl group thereof or a derivative thereof as active ingredients. By the synergistic effect of the two active ingredients, the composition is effective for noticeably preventing formation of melanin to cause freckles and spots in the skin and for noticeably whitening the skin.

  本发明公开了一种外用化学组合物，该组合物由曲酸或曲酸衍生物和具有 4 至 26 个碳原子且具有 1 至 6 个不饱和键的不饱和线性脂肪酸作为活性成分，其中不饱和键的位置在酸的烷基链上的任意位置，但与羧基相对的末端除外。通过这两种活性成分的协同作用，该组合物能有效防止黑色素的形成，防止皮肤出现雀斑和斑点，并能明显美白皮肤。
• Impact resistant thermoplastic resin composition
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0381056A2

  公开（公告）日：1990-08-08

  A composition comprising a polyphenylene ether, a poly­amide resin and a compound having an unsaturated group and a polar group in combination in the same molecule kneaded therein, and optionally an impact resistance improving material kneaded in said kneaded product. Impact resist­ance can be greatly improved as compared with the composi­tion having the all components kneaded at the same time.

  一种由聚苯醚、聚酰胺树脂和具有不饱和基团和极性基团的化合物组成的组合物，揉合在同一分子中，还可选择在所述揉合产品中揉合抗冲击性改进材料。与同时捏合所有成分的组合物相比，抗冲击性可以大大提高。