(S)-methyl 2-(2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate | 1451007-00-3

分子结构分类

有机化合物 - 有机杂环化合物 - 唑类

中文名称

——

中文别名

——

英文名称

(S)-methyl 2-(2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate

英文别名

(S)-Methyl 2-(2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate；methyl (2S)-2-[2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl]-2-[(2-methylpropan-2-yl)oxy]acetate

(S)-methyl 2-(2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate化学式

CAS

1451007-00-3

化学式

C₂₀H₂₁BrClN₃O₃

mdl

——

分子量

466.762

InChiKey

JEUHNBHHMKVRKP-KRWDZBQOSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

4.8
重原子数：

28
可旋转键数：

6
环数：

3.0
sp3杂化的碳原子比例：

0.35
拓扑面积：

65.7
氢给体数：

0
氢受体数：

5

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	(S)-methyl 2-(2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-hydroxyacetate	1567215-22-8	C₁₆H₁₃BrClN₃O₃	410.655
——	methyl 2-(2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)acetate	1567213-38-0	C₁₆H₁₃BrClN₃O₂	394.655
——	methyl 2-(2-(3-bromophenyl)-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate	1567215-19-3	C₁₆H₁₁BrClN₃O₃	408.639

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	methyl (2S)-2-[7-(8-azabicyclo[3.2.1]octan-8-yl)-2-(3-bromophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl]-2-[(2-methylpropan-2-yl)oxy]acetate	1451007-52-5	C₂₇H₃₃BrN₄O₃	541.488
——	(S,E)-methyl 2-(2-(3-bromophenyl)-7-(4-(buta-1,3-dien-1-yl)-4-methylpiperidin-1-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567216-39-0	C₃₀H₃₇BrN₄O₃	581.553
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(3-bromophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567215-32-0	C₂₉H₃₇BrN₄O₄	585.541
——	methyl (2S)-2-[7-(8-azabicyclo[3.2.1]octan-8-yl)-5-methyl-2-(3-phenylphenyl)pyrazolo[1,5-a]pyrimidin-6-yl]-2-[(2-methylpropan-2-yl)oxy]acetate	1451007-53-6	C₃₃H₃₈N₄O₃	538.69
——	(S,E)-methyl 2-(7-(4-(buta-1,3-dien-1-yl)-4-methylpiperidin-1-yl)-2-(5‘-chloro-2‘-hydroxy-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567216-51-6	C₃₆H₄₁ClN₄O₄	629.199
——	(S)-2-(2-([1,1'-biphenyl]-3-yl)-7-((1R,5S)-8-azabicyclo[3.2.1]octan-8-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetic acid	1451006-72-6	C₃₂H₃₆N₄O₃	524.663
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(2‘-hydroxy-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567215-47-7	C₃₅H₄₂N₄O₅	598.742
——	methyl (2S)-2-(tert-butoxy)-2-[(23Z,25E)-4,27-dimethyl-1,5,7,8-tetraazahexacyclo[25.2.2.1^(6,9).1^(10,14).0^(2,7).0^(15,20)]tritriaconta-2,4,6(33),8,10(32),11,13,15(20),16,18,23,25-dodecaen-3-yl]acetate	1567216-45-8	C₃₈H₄₄N₄O₃	604.792
——	methyl (2S)-2-(tert-butoxy)-2-[(23E,25E)-4,27-dimethyl-1,5,7,8-tetraazahexacyclo[25.2.2.1^(6,9).1^(10,14).0^(2,7).0^(15,20)]tritriaconta-2,4,6(33),8,10(32),11,13,15(20),16,18,23,25-dodecaen-3-yl]acetate	1567216-47-0	C₃₈H₄₄N₄O₃	604.792
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(2‘-hydroxy-4‘-methyl-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567218-11-4	C₃₆H₄₄N₄O₅	612.769
——	(2S)-2-(2-{3-[2-(but-3-en-1-yl)phenyl]phenyl}-7-{4-[(1E)-buta-1,3-dien-1-yl]-4-methylpiperidin-1-yl}-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567216-41-4	C₄₀H₄₈N₄O₃	632.846
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(5'-fluoro-2‘-hydroxy[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567217-27-9	C₃₅H₄₁FN₄O₅	616.733
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(2‘-hydroxy-5‘-methyl-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567216-07-2	C₃₆H₄₄N₄O₅	612.769
——	(2S)-methyl 2-(7-(4-(allyloxy)-4-methylpieridin-1-yl)-2-(3-(4-(but-3-en-2-yloxy)pyridin-3-yl)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567217-02-0	C₃₈H₄₇N₅O₅	653.822
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(2’-(but-3-en-1-yl)[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567215-40-0	C₃₉H₄₈N₄O₄	636.835
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(3-(4-(but-3-en-1-yl)pyridin-3-yl)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567216-24-3	C₃₈H₄₇N₅O₄	637.822
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-5-methyl-2-(2‘-(pent-4-en-1-yl)-[1,1‘-biphenyl]-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567215-90-0	C₄₀H₅₀N₄O₄	650.861
——	methyl (2S)-2-(tert-butoxy)-2-[(23Z)-4,27-dimethyl-26-oxa-1,5,7,8-tetraazahexacyclo[25.2.2.1^(6,9).1^(10,14).0^(2,7).0^(15,20)]tritriaconta-2,4,6(33),8,10(32),11,13,15(20),16,18,23-undecaen-3-yl]acetate	——	C₃₇H₄₄N₄O₄	608.781
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-5-methyl-2-(2‘-((R)-pent-4-en-2-yloxy)-[1,1‘-biphenyl]-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567215-68-2	C₄₀H₅₀N₄O₅	666.861
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-5-methyl-2-(2‘-((S)-pent-4-en-2-yloxy)-[1,1‘-biphenyl]-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567215-75-1	C₄₀H₅₀N₄O₅	666.861
——	(S,E)-methyl 2-(2-(2’-(allyloxy)-5’-chloro-[1,1‘-biphenyl]-3-yl)-7-(4-(buta-1,3-dien-1-yl)-4-methylpiperidin-1-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567216-53-8	C₃₉H₄₅ClN₄O₄	669.264
——	methyl (2S)-2-(tert-butoxy)-2-[(22R,23E)-4,22,27-trimethyl-21,26-dioxa-1,5,7,8,17-pentaazahexacyclo[25.2.2.1^(6,9).1^(10,14).0^(2,7).0^(15,20)]tritriaconta-2,4,6(33),8,10(32),11,13,15(20),16,18,23-undecaen-3-yl]acetate	1567217-13-3	C₃₆H₄₃N₅O₅	625.768
——	methyl (2S)-2-(tert-butoxy)-2-[(22S,23E)-4,22,27-trimethyl-21,26-dioxa-1,5,7,8,17-pentaazahexacyclo[25.2.2.1^(6,9).1^(10,14).0^(2,7).0^(15,20)]tritriaconta-2,4,6(33),8,10(32),11,13,15(20),16,18,23-undecaen-3-yl]acetate	1567217-18-8	C₃₆H₄₃N₅O₅	625.768
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(2‘-(allyloxy)-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate	1567215-50-2	C₃₈H₄₆N₄O₅	638.807
——	(S)-methyl 2-(7-(4-(allyloxy)-4-methylpiperidin-1-yl)-2-(2',4'-difluoro-6‘-hydroxy-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tertbutoxy)acetate	——