Methyl-α-D-idopyranosid | 35437-40-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl-α-D-idopyranosid
• 英文别名: methyl α-D-idopyranoside；Glucopyranoside, 1-O-methyl-, alpha-D-；(2R,3R,4R,5S,6S)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol
• CAS: 35437-40-2
• 化学式: C₇H₁₄O₆
• 分子量: 194.185
• InChiKey: HOVAGTYPODGVJG-UOYQFSTFSA-N

物化性质

• 沸点：
  389.1±42.0 °C(Predicted)
• 密度：
  1.47±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  Methyl-α-D-idopyranosid 在 palladium on activated charcoal 氢气 、 对甲苯磺酸 、 三甲胺 作用下， 以 1,4-二氧六环 、 甲醇 、 溶剂黄146 、 N,N-二甲基甲酰胺 、 苯 为溶剂， 反应 16.0h， 生成 methyl α-D-idopyranoside 2,3-carbonate
  参考文献：
  名称：

  The 4,6-benzylidene acetals, and the conformation, of methyl α-d-idopyranoside

  摘要：

  DOI：

  10.1016/s0008-6215(00)85675-x
• 作为产物：
  描述：

  methyl α-D-lyxo-hexopyranosid-4-ulose 生成 Methyl-α-D-idopyranosid
  参考文献：
  名称：

  TSUDA, YOSHISUKE;HANAJIMA, MAKIKO;MATSUHIRA, NAOHISA;OKUNO, YUKIHIRO;KANE+, CHEM. AND PHARM. BULL., 37,(1989) N, C. 2344-2350

  摘要：

  DOI：

文献信息

• Formyloxyacetoxyphenylmethane and 1,1-diacylals as versatile O-formylating and O-acylating reagents for alcohols
  作者：Robert S.L. Chapman、Molly Francis、Ruth Lawrence、Joshua D. Tibbetts、Steven D. Bull

  DOI：10.1016/j.tet.2018.09.014

  日期：2018.11

  Formyloxyacetoxyphenylmethane, symmetric 1,1-diacylals and mixed 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as moisture stable O-formylating and O-acylating reagents for primary and secondary alcohols, allylic alcohols and phenols under solvent/catalyst free conditions to afford their corresponding esters in good yield.

  在无溶剂/催化剂的情况下，甲氧基乙氧基苯基甲烷，对称的1,1-二醛和混合的1-新戊氧基-1-酰氧基-1-苯基甲烷已被用作伯，仲醇，烯丙基醇和苯酚的湿气稳定的O-甲酰化和O-酰化试剂。条件以高收率得到其相应的酯。
• POLYMER STABILIZER
  申请人：KIMURA Yoshikazu

  公开号：US20100179253A1

  公开（公告）日：2010-07-15

  A polymer stabilizer comprising the following alkoxy compound: the alkoxy compound: a compound obtained by alkoxylating at least one hydroxyl group contained in a compound of the following formula (1) containing one formyl group or carbonyl group and (n− 1 ) hydroxyl groups in the molecule with an alkyl group having 1 to 12 carbon atoms: C n H 2n O n (1) (wherein, n represents an integer of 3 or more).

  一种聚合物稳定剂，包含以下烷氧基化合物：所述烷氧基化合物是通过将含有以下通式（1）中的一个甲酰基或羰基以及分子中（n-1）个羟基的化合物中的至少一个羟基进行烷氧基化而得到的化合物，其中烷基团含有1至12个碳原子：CnH2nOn（1）（其中，n代表3或以上的整数）。
• Utilization of Sugars in Organic Synthesis; Part XXVII. Chemistry of Oxo-Sugars. (2). Regio- and Stereo-Selective Synthesis of Methyl D-Hexopyranosiduloses and Identification of Their Forms Existing in Solutions.
  作者：Hong-Min LIU、Yoshiyuki SATO、Yoshisuke TSUDA

  DOI：10.1248/cpb.41.491

  日期：——

  Sixteen oxo derivatives of methyl D-hexopyranosides with various regio- and stereo-chemistries were selectively synthesized by direct oxidation of non-protected methyl glycosides by the bistributyltin oxide-bromine method or by oxidation of pfrtially protected glycosides followed by deprotection. The forms of these oxoglycosides existing in pryidine-d5 and in H2O (D2O) were investigated by means of 13C-NMR spectroscopy, and it was found that interconversion between oxo and hydrate forms of oxoglycosides readily takes place.

  通过双二丁基氧化锡-溴法直接氧化未受保护的甲基糖苷，或先氧化受部分保护的糖苷再进行脱保护，选择性地合成了十六种具有不同区域和立体化学结构的甲基 D-吡喃己苷的氧化衍生物。通过 13C-NMR 光谱法研究了这些氧化糖苷在 Pryidine-d5 和 H2O（D2O）中的存在形式，发现氧化糖苷的氧化形式和水合物形式之间很容易发生相互转化。
• THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER
  申请人：Kimura Yoshikazu

  公开号：US20130032756A1

  公开（公告）日：2013-02-07

  The present invention provides a thermoplastic polymer composition containing a particular phenol compound or organic phosphoric compound, compound (9) which is compound (9a) represented by C m H 2m O m wherein m is an integer of not less than 3 and not more than 10, and having one aldehyde group or ketone group and m−1 hydroxy groups with at least one hydroxy group having been replaced by an alkoxy group represented by —OR 26 wherein R 26 is a C 1-12 alkyl group, and a thermoplastic polymer, and a processing stabilizer containing a particular phenol compound or organic phosphoric compound, and compound (9). A combined use of a particular phenol compound or organic phosphoric compound and compound (9) can improve processing stability of a thermoplastic polymer composition.

  本发明提供了一种热塑性聚合物组合物，其中包含特定的酚化合物或有机磷化合物、化合物(9)，该化合物(9)表示为CmH2mOm，其中m是不小于3且不大于10的整数，具有一个醛基或酮基和m-1个羟基，其中至少一个羟基已被一个表示为—OR26的烷氧基所取代，其中R26是C1-12烷基，以及一种热塑性聚合物和一种加工稳定剂，该加工稳定剂包含特定的酚化合物或有机磷化合物和化合物(9)。特定的酚化合物或有机磷化合物和化合物(9)的联合使用可以提高热塑性聚合物组合物的加工稳定性。
• Polymer stabilizer
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2206740A2

  公开（公告）日：2010-07-14

  A polymer stabilizer comprising the following alkoxy compound: the alkoxy compound: a compound obtained by alkoxylating at least one hydroxyl group contained in a compound of the following formula (1) containing one formyl group or carbonyl group and (n-1) hydroxyl groups in the molecule with an alkyl group having 1 to 12 carbon atoms:          CnH2nOn     (1) (wherein n represents an integer of 3 or more).

  一种由下述烷氧基化合物组成的聚合物稳定剂： 烷氧基化合物：通过将分子中含有一个甲酰基或羰基和（n-1）个羟基的下式 （1）化合物中所含的至少一个羟基与具有 1 至 12 个碳原子的烷基进行烷氧基化而得 到的化合物： CnH2nOn (1) (其中 n 代表 3 个或更多的整数）。