A convenient synthesis of 2-deoxy-2-(d- and -(l-3-hydroxytetradecanoyl-amino)-d-glucose: diastereoisomers of the monomeric, lipid A component of the bacterial Iipopolysaccharide
Lipid A and Related Compounds. XXIX. Synthesis of Biologically Active N-Acylated L-Asparagine-Containing D-Glucosamine Derivatives Structurally Related to Lipid A.
New beta-N-acylated L-asparagine-linked D-glucosamine derivatives, in which the reducing unit of lipid A has been mimicked by a lipoamino acid, have been synthesized. Compounds 1 and 2 exhibit mitogenicity and nitric oxide (NO) productivity.
A convenient synthesis of 2-deoxy-2-(d- and -(l-3-hydroxytetradecanoyl-amino)-d-glucose: diastereoisomers of the monomeric, lipid A component of the bacterial Iipopolysaccharide