6-O-benzyl-2,3,4-tri-O-methyl-D-glucono-1,5-lactone | 541550-92-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-O-benzyl-2,3,4-tri-O-methyl-D-glucono-1,5-lactone
• 英文别名: (3R,4S,5R,6R)-3,4,5-trimethoxy-6-(phenylmethoxymethyl)oxan-2-one
• CAS: 541550-92-9
• 化学式: C₁₆H₂₂O₆
• 分子量: 310.347
• InChiKey: RBSOIUUBACUOTJ-APIJFGDWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  63.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  6-O-benzyl-2,3,4-tri-O-methyl-D-glucono-1,5-lactone 在 palladium on activated charcoal 氢氧化钾 、 氢气 作用下， 以 四氢呋喃 、 乙酸乙酯 为溶剂， 反应 48.0h， 生成 2,3,4,5-tetra-O-methyl-D-gluconic acid
  参考文献：
  名称：

  Synthesis of 2,3,4,5-tetra-O-methyl-d-glucono-1,6-lactone as a monomer for the preparation of copolyesters

  摘要：

  2,3,4,5-Tetra-O-methyl-D-glucono-1,6-lactone has been prepared as a crystalline compound in acceptable yield by two different routes. An initial assay of copolymerization with L-lactide by ring-opening polymerization was carried out. The incorporation of the carbohydrate monomer into the polymer chain was about 2%. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(02)00528-1
• 作为产物：
  描述：

  1,2,3,4-tetra-O-methyl-α-D-glucopyranose 在 硫酸 、 乙酸酐 、 sodium hydride 作用下， 以 四氢呋喃 、 溶剂黄146 、 二甲基亚砜 为溶剂， 反应 48.0h， 生成 6-O-benzyl-2,3,4-tri-O-methyl-D-glucono-1,5-lactone
  参考文献：
  名称：

  Synthesis of 2,3,4,5-tetra-O-methyl-d-glucono-1,6-lactone as a monomer for the preparation of copolyesters

  摘要：

  2,3,4,5-Tetra-O-methyl-D-glucono-1,6-lactone has been prepared as a crystalline compound in acceptable yield by two different routes. An initial assay of copolymerization with L-lactide by ring-opening polymerization was carried out. The incorporation of the carbohydrate monomer into the polymer chain was about 2%. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(02)00528-1

文献信息

• Synthesis of 2,3,4,5-tetra-O-methyl-d-glucono-1,6-lactone as a monomer for the preparation of copolyesters
  作者：Inmaculada Molina Pinilla、Manuel Bueno Martı́nez、Juan A Galbis

  DOI：10.1016/s0008-6215(02)00528-1

  日期：2003.3

  2,3,4,5-Tetra-O-methyl-D-glucono-1,6-lactone has been prepared as a crystalline compound in acceptable yield by two different routes. An initial assay of copolymerization with L-lactide by ring-opening polymerization was carried out. The incorporation of the carbohydrate monomer into the polymer chain was about 2%. (C) 2003 Elsevier Science Ltd. All rights reserved.