6-O-benzyl-2,3,4,5-tetra-O-methyl-D-gluconic acid | 541550-93-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-O-benzyl-2,3,4,5-tetra-O-methyl-D-gluconic acid
• 英文别名: (2R,3S,4R,5R)-2,3,4,5-tetramethoxy-6-phenylmethoxyhexanoic acid
• CAS: 541550-93-0
• 化学式: C₁₇H₂₆O₇
• 分子量: 342.389
• InChiKey: WOIOMFXUQWBKRI-LVQVYYBASA-N

物化性质

• 沸点：
  458.8±45.0 °C(Predicted)
• 密度：
  1.146±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  24
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  83.4
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  6-O-benzyl-2,3,4,5-tetra-O-methyl-D-gluconic acid 在 palladium on activated charcoal 氢气 作用下， 以 乙酸乙酯 为溶剂， 反应 24.0h， 以82%的产率得到2,3,4,5-tetra-O-methyl-D-gluconic acid
  参考文献：
  名称：

  Synthesis of 2,3,4,5-tetra-O-methyl-d-glucono-1,6-lactone as a monomer for the preparation of copolyesters

  摘要：

  2,3,4,5-Tetra-O-methyl-D-glucono-1,6-lactone has been prepared as a crystalline compound in acceptable yield by two different routes. An initial assay of copolymerization with L-lactide by ring-opening polymerization was carried out. The incorporation of the carbohydrate monomer into the polymer chain was about 2%. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(02)00528-1
• 作为产物：
  描述：

  1,2,3,4-tetra-O-methyl-α-D-glucopyranose 在 氢氧化钾 、 硫酸 、 乙酸酐 、 sodium hydride 作用下， 以 四氢呋喃 、 溶剂黄146 、 二甲基亚砜 为溶剂， 反应 72.0h， 生成 6-O-benzyl-2,3,4,5-tetra-O-methyl-D-gluconic acid
  参考文献：
  名称：

  Synthesis of 2,3,4,5-tetra-O-methyl-d-glucono-1,6-lactone as a monomer for the preparation of copolyesters

  摘要：

  2,3,4,5-Tetra-O-methyl-D-glucono-1,6-lactone has been prepared as a crystalline compound in acceptable yield by two different routes. An initial assay of copolymerization with L-lactide by ring-opening polymerization was carried out. The incorporation of the carbohydrate monomer into the polymer chain was about 2%. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(02)00528-1

文献信息

• Synthesis of 2,3,4,5-tetra-O-methyl-d-glucono-1,6-lactone as a monomer for the preparation of copolyesters
  作者：Inmaculada Molina Pinilla、Manuel Bueno Martı́nez、Juan A Galbis

  DOI：10.1016/s0008-6215(02)00528-1

  日期：2003.3

  2,3,4,5-Tetra-O-methyl-D-glucono-1,6-lactone has been prepared as a crystalline compound in acceptable yield by two different routes. An initial assay of copolymerization with L-lactide by ring-opening polymerization was carried out. The incorporation of the carbohydrate monomer into the polymer chain was about 2%. (C) 2003 Elsevier Science Ltd. All rights reserved.