(RS)-3-methylaminobutyric acid hydrochloride | 167222-94-8

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (RS)-3-methylaminobutyric acid hydrochloride
• 英文别名: 3-(Methylamino)butanoic acid hydrochloride；3-(methylamino)butanoic acid;hydrochloride
• CAS: 167222-94-8
• 化学式: C₅H₁₁NO₂*ClH
• 分子量: 153.609
• InChiKey: IDYRLRYWPQNZMO-UHFFFAOYSA-N

物化性质

• 熔点：
  141-142 °C
• 沸点：
  215.4±23.0 °C(Predicted)
• 密度：
  1.019±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.49
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  49.3
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2922499990

反应信息

• 作为产物：
  描述：

  1,2-二甲基-2,3-二氢-4(1H)-吡啶酮 在 sodium periodate 、 sodium hydroxide 作用下， 以 水 为溶剂， 反应 26.0h， 以94%的产率得到(RS)-3-methylaminobutyric acid hydrochloride
  参考文献：
  名称：

  Synthesis of β-Amino Acids Based on Oxidative Cleavage of Dihydropyridone Derivatives

  摘要：

  A new method for the synthesis of beta-amino acids based on 2,3-dihydropyridones as starting materials is presented. Conversions of 2,3-dihydropyridones with NalO(4) and subsequently with base gave the corresponding beta-amino acids in a one-pot procedure. The reactions have been monitored by H-1 NMR indicating that the beta-amino acids were formed in quantitative yields mostly. This method appears to be of broad scope, as 2-substituted 2,3-dihydropyridones are easily accessible via N-acyliminium ions generated from 4-methoxypyridine.

  DOI：

  10.1021/ol0485518

文献信息

• POLYARYLENE SULFIDE PREPARATION METHOD
  申请人：LG Chem, Ltd.

  公开号：EP3608351A1

  公开（公告）日：2020-02-12

  The present disclosure relates to a preparation method of a polyarylene sulfide, and this method may produce a polyarylene sulfide having properties equal to or higher than those of the conventional method at a high yield by adding an aliphatic amino acid hydrochloride in addition to existing materials for dehydration.

  本公开涉及一种聚芳基硫醚的制备方法，该方法通过在现有脱水材料中添加脂肪族氨基酸盐酸盐，可以高产率生产出性能等于或高于传统方法的聚芳基硫醚。
• Preparation method of polyarylene sulfide
  申请人：LG CHEM, LTD.

  公开号：US11192980B2

  公开（公告）日：2021-12-07

  The present disclosure relates to a preparation method of a polyarylene sulfide, and this method may produce a polyarylene sulfide having properties equal to or higher than those of the conventional method at a high yield by adding an aliphatic amino acid hydrochloride in addition to existing materials for dehydration.

  本公开涉及一种聚芳基硫醚的制备方法，该方法通过在现有脱水材料中添加脂肪族氨基酸盐酸盐，可以高产率生产出性能等于或高于传统方法的聚芳基硫醚。
• PREPARATION METHOD OF POLYARYLENE SULFIDE
  申请人：LG CHEM, LTD.

  公开号：US20210171715A1

  公开（公告）日：2021-06-10

  The present disclosure relates to a preparation method of a polyarylene sulfide, and this method may produce a polyarylene sulfide having properties equal to or higher than those of the conventional method at a high yield by adding an aliphatic amino acid hydrochloride in addition to existing materials for dehydration.