Methyl 2,4-di-O-acetyl-3-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-6-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside | 129870-12-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl 2,4-di-O-acetyl-3-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-6-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside
• CAS: 129870-12-8；129939-85-1
• 化学式: C₇₉H₇₈O₂₂
• 分子量: 1379.48
• InChiKey: WFKBOHXFBYXXKI-LJGKUPGXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.58
• 重原子数：
  101.0
• 可旋转键数：
  30.0
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  250.1
• 氢给体数：
  0.0
• 氢受体数：
  22.0

反应信息

• 作为反应物：
  描述：

  Methyl 2,4-di-O-acetyl-3-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-6-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside 在 palladium on activated charcoal 氢气 、 sodium methylate 作用下， 生成 Methyl 3-O-α-D-galactopyranosyl-6-O-α-D-mannopyranosyl-α-D-mannopyranoside
  参考文献：
  名称：

  Synthesis of methyl 3-O-α-d-galactopyranosyl-6-O-α-d-mannopyranosyl-α-d-mannopyranoside, methyl 3-O-α-d-glucopyranosyl-6-O-α-d-mannopyranosyl-α-d-mannopyranoside, methyl 6-O-α-d-galactopyranosyl-3-O-α-d-mannopyranosyl-α-d-mannopyranoside, and methyl 6-O-α-d-glucopyranosyl-3-O-α-d-mannopyranosyl-α-d-mannopyranoside

  摘要：

  DOI：

  10.1016/0008-6215(90)80057-a
• 作为产物：
  描述：

  methyl 2,4-di-O-acetyl-6-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside 、 2,3,4,6-tetra-O-benzyl-D-galactopyranosyl bromide 在 molecular sieve 、 四乙基溴化铵 作用下， 以 1,2-二氯乙烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以83%的产率得到Methyl 2,4-di-O-acetyl-3-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-6-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside
  参考文献：
  名称：

  Synthesis of methyl 3-O-α-d-galactopyranosyl-6-O-α-d-mannopyranosyl-α-d-mannopyranoside, methyl 3-O-α-d-glucopyranosyl-6-O-α-d-mannopyranosyl-α-d-mannopyranoside, methyl 6-O-α-d-galactopyranosyl-3-O-α-d-mannopyranosyl-α-d-mannopyranoside, and methyl 6-O-α-d-glucopyranosyl-3-O-α-d-mannopyranosyl-α-d-mannopyranoside

  摘要：

  DOI：

  10.1016/0008-6215(90)80057-a

文献信息

• Synthesis of methyl 3-O-a-d-galactopyranosyl-6-O-a-d-mannopyranosyl-a-d-mannopyranoside, methyl 3-O-a-d-glucopyranosyl-6-O-a-d-mannopyranosyl-a-d-mannopyranoside, methyl 6-O-a-d-galactopyranosyl-3-O-a-d-mannopyranosyl-a-d-mannopyranoside, and methyl 6-O-a-d-glucopyranosyl-3-O-a-d-mannopyranosyl-a-d-mannopyranoside
  作者：Per J. Garegg、Stefan Oscarson、Anna-Karin Tidén

  DOI：10.1016/0008-6215(90)84213-e

  日期：1990.4