6-methyloxy-7-(4-(3-(piperidin-1-yl)propoxy))-4-quiolinol | 1436417-97-8

分子结构分类

有机化合物 - 有机杂环化合物 - 喹啉及其衍生物

中文名称

——

中文别名

——

英文名称

6-methyloxy-7-(4-(3-(piperidin-1-yl)propoxy))-4-quiolinol

英文别名

6-methyloxy-7-(3-(piperidin-1-yl)propoxy)-4-quinolinol；6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-ol

6-methyloxy-7-(4-(3-(piperidin-1-yl)propoxy))-4-quiolinol化学式

CAS

1436417-97-8

化学式

C₁₈H₂₄N₂O₃

mdl

——

分子量

316.4

InChiKey

GNEHZWCDWMNKAA-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

3.2
重原子数：

23.0
可旋转键数：

6.0
环数：

3.0
sp3杂化的碳原子比例：

0.5
拓扑面积：

54.82
氢给体数：

1.0
氢受体数：

5.0

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	7-(3-chloropropoxy)-6-methoxy-4(1H)-quinolinone	1428788-16-2	C₁₃H₁₄ClNO₃	267.712

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	4-chloro-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinoline	861881-05-2	C₁₈H₂₃ClN₂O₂	334.846
——	3-fluoro-4-(6-methoxy-7-(3-(piperdine-1-yl)propoxy)quinolin-4-yloxy)aniline	960299-69-8	C₂₄H₂₈FN₃O₃	425.503
——	3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)-quinolin-4-yloxy)benzaldehyde	1428788-22-0	C₂₅H₂₇FN₂O₄	438.499
——	4-(2-fluoro-4-isothiocyanatophenoxy)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinoline	1428788-20-8	C₂₅H₂₆FN₃O₃S	467.564
——	4-(2-fluoro-4-nitrophenoxy)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinoline	1436418-00-6	C₂₄H₂₆FN₃O₅	455.486
——	4-(4-(7-(3-(piperidin-1-yl)propoxy)-6-methoxyquinolin-4-yloxy)-3-fluorophenyl)thiosemicarbazide	1428788-21-9	C₂₅H₃₀FN₅O₃S	499.609
——	N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)-quinolin-4-yloxy)phenyl)semicarbazide	1449763-34-1	C₂₅H₃₀FN₅O₄	483.543
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2-methylpropylidene)semicarbazide	1449763-17-0	C₂₉H₃₆FN₅O₄	537.634
——	phenyl 3-fluoro-4-(6-methoxy-7-(3-(piperdine-1-yl)propoxy)-quinolin-4-yloxy)phenylcarbamate	1449763-31-8	C₃₁H₃₂FN₃O₅	545.611
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(benzylidene)semicarbazide	1428787-51-2	C₃₂H₃₄FN₅O₄	571.651
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(4-fluorobenzylidene)semicarbazide	1428787-57-8	C₃₂H₃₃F₂N₅O₄	589.642
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(4-chlorobenzylidene)semicarbazide	1449763-26-1	C₃₂H₃₃ClFN₅O₄	606.097
——	(E)-N¹-(3-fluoro-4-((6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-N⁴-(4-(dimethylamino)benzylidene)semicarbazide	——	C₃₄H₃₉FN₆O₄	614.72
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-((1H-pyrrol-2-yl)methylene)semicarbazide	1449763-16-9	C₃₀H₃₃FN₆O₄	560.628
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-((pyridin-3-yl)methylene)semicarbazide	1449763-14-7	C₃₁H₃₃FN₆O₄	572.639
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-((furan-2-yl)methylene)thiosemicarbazide	1449763-19-2	C₃₀H₃₂FN₅O₄S	577.68
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2-fluorobenzylidene)semicarbazide	1449763-04-5	C₃₂H₃₃F₂N₅O₄	589.642
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(3-methoxybenzylidene)semicarbazide	1428787-55-6	C₃₃H₃₆FN₅O₅	601.678
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-((furan-2-yl)methylene)semicarbazide	1449763-15-8	C₃₀H₃₂FN₅O₅	561.613
——	(E)-N⁴-(2-fluorophenyl)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)benzylidene)semicarbazide	1428787-93-2	C₃₂H₃₃F₂N₅O₄	589.642
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(3,4-difluorobenzylidene)semicarbazide	1449763-03-4	C₃₂H₃₂F₃N₅O₄	607.632
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(1-phenylethylidene)semicarbazide	1428787-63-6	C₃₃H₃₆FN₅O₄	585.678
——	(E)-N¹-(3,4-difluorophenyl)-N⁴-(3-fluoro-4-((6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yl)oxy)benzylidene)semicarbazide	——	C₃₂H₃₂F₃N₅O₄	607.632
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(4-nitrobenzylidene)semicarbazide	1449763-10-3	C₃₂H₃₃FN₆O₆	616.649
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2,4-difluorobenzylidene)thiosemicarbazide	1449763-18-1	C₃₂H₃₂F₃N₅O₃S	623.699
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2,4,6-trimethylbenzylidene)semicarbazide	1449763-13-6	C₃₅H₄₀FN₅O₄	613.732
——	(E)-N⁴-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinoline-4-yloxy)phenyl)-N¹-(2-chloro-4-fluorobenzylidene)thiosemicarbazide	——	C₃₂H₃₂ClF₂N₅O₃S	640.154
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2,4-difluorobenzylidene)semicarbazide	1449763-05-6	C₃₂H₃₂F₃N₅O₄	607.632
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2-cyanobenzylidene)semicarbazide	1449763-08-9	C₃₃H₃₃FN₆O₄	596.661
——	(E)-N¹-(3-fluoro-4-((6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-N⁴-(2,4-dichlorobenzylidene)semicarbazide	——	C₃₂H₃₂Cl₂FN₅O₄	640.542
——	(E)-N¹-(3-fluoro-4-((6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-N⁴-(2-chloro-4-fluorobenzylidene)semicarbazide	——	C₃₂H₃₂ClF₂N₅O₄	624.087
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(1-phenylpropylidene)semicarbazide	1428787-76-1	C₃₄H₃₈FN₅O₄	599.705
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(3-nitrobenzylidene)semicarbazide	1449763-09-0	C₃₂H₃₃FN₆O₆	616.649
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2,5-dimethoxybenzylidene)semicarbazide	1449763-12-5	C₃₄H₃₈FN₅O₆	631.704
——	N-[3-fluoro-4-[[6-methoxy-7-[3-(1-piperidinyl)propoxy]quinoline-4-yl]oxy]phenyl]-4-chloropyridine-2-carboxamide	1491141-85-5	C₃₀H₃₀ClFN₄O₄	565.044
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2-trifluoromethylbenzylidene)semicarbazide	1449763-07-8	C₃₃H₃₃F₄N₅O₄	639.65
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2-nitrobenzylidene)thiosemicarbazide	1428787-80-7	C₃₂H₃₃FN₆O₅S	632.716
——	(E)-N¹-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N⁴-(2-nitrobenzylidene)semicarbazide	1449763-11-4	C₃₂H₃₃FN₆O₆	616.649

反应信息

作为反应物：

描述：

6-methyloxy-7-(4-(3-(pip