Acetic acid (2S,4aR,5S,8aR)-5-(2-{(1S,4aR,8aR)-6-[(E)-hydroxyimino]-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-ethyl)-1,1,4a-trimethyl-6-methylene-decahydro-naphthalen-2-yl ester | 110743-37-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Acetic acid (2S,4aR,5S,8aR)-5-(2-{(1S,4aR,8aR)-6-[(E)-hydroxyimino]-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-ethyl)-1,1,4a-trimethyl-6-methylene-decahydro-naphthalen-2-yl ester
• CAS: 110743-37-8
• 化学式: C₃₂H₅₁NO₃
• 分子量: 497.762
• InChiKey: UPQAKJFOSPHINB-AJMZXQJTSA-N

反应信息

• 作为反应物：
  描述：

  Acetic acid (2S,4aR,5S,8aR)-5-(2-{(1S,4aR,8aR)-6-[(E)-hydroxyimino]-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-ethyl)-1,1,4a-trimethyl-6-methylene-decahydro-naphthalen-2-yl ester 在 对甲苯磺酰氯 作用下， 以 吡啶 为溶剂， 以29%的产率得到Acetic acid (2S,4aR,5S,8aR)-5-{2-[(1S,5S,6S)-6-(2-cyano-ethyl)-5-isopropenyl-2,6-dimethyl-cyclohex-2-enyl]-ethyl}-1,1,4a-trimethyl-6-methylene-decahydro-naphthalen-2-yl ester
  参考文献：
  名称：

  Regioselective reduction of .ALPHA.,.GAMMA.-onoceradienedione : Synthesis of lansiolic acid.

  摘要：

  Synthesis of lansiolic acid is completed through the regioselective reduction of α, γ-onoceradienedione as a key step, and this unique regioselectivity is discussed based on the conformation analysis of 3-keto-4, 4, 10-trimethyldecalin system.

  DOI：

  10.1248/cpb.34.4443
• 作为产物：
  描述：

  乙酸酐 、 (4aR,5S,8aR)-5-[2-((1S,4aR,6S,8aR)-6-Hydroxy-5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-yl)-ethyl]-1,1,4a,6-tetramethyl-3,4,4a,5,8,8a-hexahydro-1H-naphthalen-2-one 在 4-二甲氨基吡啶 、 羟胺 作用下， 以 吡啶 为溶剂， 以73%的产率得到Acetic acid (2S,4aR,5S,8aR)-5-(2-{(1S,4aR,8aR)-6-[(E)-hydroxyimino]-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-ethyl)-1,1,4a-trimethyl-6-methylene-decahydro-naphthalen-2-yl ester
  参考文献：
  名称：

  Regioselective reduction of .ALPHA.,.GAMMA.-onoceradienedione : Synthesis of lansiolic acid.

  摘要：

  Synthesis of lansiolic acid is completed through the regioselective reduction of α, γ-onoceradienedione as a key step, and this unique regioselectivity is discussed based on the conformation analysis of 3-keto-4, 4, 10-trimethyldecalin system.

  DOI：

  10.1248/cpb.34.4443