(-)-menthyltributyltin | 764661-20-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (-)-menthyltributyltin
• CAS: 764661-20-3
• 化学式: C₂₂H₄₆Sn
• 分子量: 429.317
• InChiKey: KSZYEUNDJPZWEW-IJBXMQGASA-N

物化性质

• 沸点：
  415.8±28.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  23
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  三丁基氯化锡 、 magnesium,(1S,4S)-1-methyl-4-propan-2-ylcyclohexane,chloride 以 四氢呋喃 为溶剂， 反应 20.0h， 以87%的产率得到(-)-menthyltributyltin
  参考文献：
  名称：

  Pt-based chiral organotin modified heterogeneous catalysts for the enantioselective hydrogenation of 3,4-hexanedione

  摘要：

  In this paper we have studied the liquid-phase enantioselective hydrogenation of 3,4-hexanedione using Pt-based catalysts, modified with chiral organotin compounds derived from the (-)-menthyl group: (-)-Pt-MenSnBu(3) and (-)-Men(3)Sn-Sn-(-)-Men(3). The organotin chiral modifiers were carefully synthesized and characterized in order to obtain optically pure compounds. The catalysts were prepared through a controlled surface reaction between the supported transition metal and the organometallic compound, using techniques derived from Surface Organometallic Chemistry on Metals (SOMC/M). The organobimetallic catalytic systems were found to be active and enantioselective in the hydrogenation of 3,4-hexanedione, yielding an enantiomeric excess of 25-27% for 4-hydroxy-3-hexanone. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.apcata.2012.08.031

文献信息

• Pt-based chiral organotin modified heterogeneous catalysts for the enantioselective hydrogenation of 3,4-hexanedione
  作者：Virginia Vetere、María B. Faraoni、Julio C. Podestá、Mónica L. Casella

  DOI：10.1016/j.apcata.2012.08.031

  日期：2012.11

  In this paper we have studied the liquid-phase enantioselective hydrogenation of 3,4-hexanedione using Pt-based catalysts, modified with chiral organotin compounds derived from the (-)-menthyl group: (-)-Pt-MenSnBu(3) and (-)-Men(3)Sn-Sn-(-)-Men(3). The organotin chiral modifiers were carefully synthesized and characterized in order to obtain optically pure compounds. The catalysts were prepared through a controlled surface reaction between the supported transition metal and the organometallic compound, using techniques derived from Surface Organometallic Chemistry on Metals (SOMC/M). The organobimetallic catalytic systems were found to be active and enantioselective in the hydrogenation of 3,4-hexanedione, yielding an enantiomeric excess of 25-27% for 4-hydroxy-3-hexanone. (C) 2012 Elsevier B.V. All rights reserved.