5-iodo-3'O,5'O-bis(tert-butyldimethylsilyl)-2'-deoxycytidine | 478843-96-8

分子结构分类

有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷

中文名称

——

中文别名

——

英文名称

5-iodo-3'O,5'O-bis(tert-butyldimethylsilyl)-2'-deoxycytidine

英文别名

3',5'-(tertbutyldimethylsilyl)-5-(iodo)deoxycytidine；3',5'-bis(tert-butyidimethyisilyl)-5-iodo-2'-deoxycytidine；3',5'-bis(tertbutyldimethylsilyl)-5-(iodo)deoxycytidine；3',5'-(teributyldimethyisilyl)-5-(iodo)deoxycytidine；4-amino-1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-iodopyrimidin-2-one

5-iodo-3'O,5'O-bis(tert-butyldimethylsilyl)-2'-deoxycytidine化学式

CAS

478843-96-8

化学式

C₂₁H₄₀IN₃O₄Si₂

mdl

——

分子量

581.642

InChiKey

CHAXEGFFQDCRTF-GVDBMIGSSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

5.13
重原子数：

31
可旋转键数：

8
环数：

2.0
sp3杂化的碳原子比例：

0.81
拓扑面积：

86.4
氢给体数：

1
氢受体数：

4

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
2',3'-二-O-(叔-丁基二甲基硅烷基)-2'-脱氧胞苷	2'-deoxy-3',5'-bis-O-(tert-butyldimethylsilyl)cytidine	51549-29-2	C₂₁H₄₁N₃O₄Si₂	455.745
5-碘-2'-脱氧胞苷	5-Iodo-2'-deoxycytidine	611-53-0	C₉H₁₂IN₃O₄	353.116
2'-脱氧胞嘧啶核苷	2'-Deoxycytidine	951-77-9	C₉H₁₃N₃O₄	227.22

下游产品

中文名称	英文名称	CAS号	化学式	分子量
2',3'-二-O-(叔-丁基二甲基硅烷基)-2'-脱氧胞苷	2'-deoxy-3',5'-bis-O-(tert-butyldimethylsilyl)cytidine	51549-29-2	C₂₁H₄₁N₃O₄Si₂	455.745
——	3',5'-(tertbutyldimethylsilyl)-5-(hydroxymethylen)deoxycytidine	1257247-39-4	C₂₂H₄₃N₃O₅Si₂	485.772
——	3',5'-(tertbutyldimethylsilyl)-5-(formyl)deoxycytidine	1257247-38-3	C₂₂H₄₁N₃O₅Si₂	483.756
——	3',5'-O-bis(tert-butyldimethylsilyl)-5-([D3]methyl)-2'-deoxycytidine	1245724-75-7	C₂₂H₄₃N₃O₄Si₂	472.748
——	N⁴,N⁴-dibenzoyl-1-[2'-deoxy-3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-erythro-pentofuranosyl]-5-iodocytosine	515850-82-5	C₃₅H₄₈IN₃O₆Si₂	789.858
——	5-carboxylmethyl-3',5'-(tert-butyldimethylsilyl)-2'-deoxycytidine	1361013-63-9	C₂₃H₄₃N₃O₆Si₂	513.782
——	Naphthalene-1-carboxylic acid {1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-iodo-2-oxo-1,2-dihydro-pyrimidin-4-yl}-(naphthalene-1-carbonyl)-amide	610303-48-5	C₄₃H₅₂IN₃O₆Si₂	889.978
——	3',5'-(tertbutyldimethylsilyl)-4,5-(1,3-[3H,6H]oxazin-2-one)deoxycytidine	1257247-40-7	C₂₃H₄₁N₃O₆Si₂	511.766
——	5-[3-(6-dimethylaminonaphthalen-2-yl)-3-hydroxy-1-propyn-1-yl]-3'O,5'O-bis(tert-butyldimethylsilyl)-2'-deoxycytidine	936855-20-8	C₃₆H₅₄N₄O₅Si₂	679.02
——	3',5'-(tert-butyldimethylsilyl)-4-N-benzoyl-5-formyl-2'deoxycytidine	1361013-57-1	C₂₉H₄₅N₃O₆Si₂	587.864
——	3',5'-(tert-butyldimethylsilyl)-4-N-acetyl-5-carboxymethyl-2'deoxycytidine	1361013-61-7	C₂₅H₄₅N₃O₇Si₂	555.819
——	N-benzoyl-N-(1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-formyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide	1361013-64-0	C₃₆H₄₉N₃O₇Si₂	691.972
——	5-formyl-2'-deoxycytidine	137017-45-9	C₁₀H₁₃N₃O₅	255.23
5-甲基-2’-脱氧胞苷-d3	D₃-5-methyl-2’-deoxycytidine	1160707-78-7	C₁₀H₁₅N₃O₄	244.223
——	N⁵-benzoyl-2-[2'-deoxy-3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-erythro-pentofuranosyl]pyrimido[4,5-c]isoquinoline-3,6-dione	515850-83-6	C₃₅H₄₇N₃O₆Si₂	661.946
——	4,5-(1,3-[3H,6H]oxazin-2-one)deoxycytidine	1257247-41-8	C₁₁H₁₃N₃O₆	283.241
——	3-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-12-(naphthalene-1-carbonyl)-3H,12H-1,3,12-triaza-chrysene-2,11-dione	610303-49-6	C₄₃H₅₁N₃O₆Si₂	762.065
——	N-benzoyl-5-formyl-2'-deoxycytidine	1361013-59-3	C₁₇H₁₇N₃O₆	359.338
——	2-[2'-deoxy-β-D-erythro-pentofuranosyl]pyrimido[4,5-c]isoquinoline-3,6(5H)-dione	108642-35-9	C₁₆H₁₅N₃O₅	329.312
——	3-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-3H,12H-1,3,12-triaza-chrysene-2,11-dione	610303-50-9	C₂₀H₁₇N₃O₅	379.372
——	5-methoxycarbonyl-N4-acetyl-2'-deoxycytidine	1311141-23-7	C₁₃H₁₇N₃O₇	327.294
——	5'-(dimethoxytrityl)-4,5-(1,3-[3H,6H]oxazin-2-one)deoxycytidine	1257247-43-0	C₃₂H₃₁N₃O₈	585.613
——	5'-(4,4'-dimethoxytrityl)-4-N-benzoyl-5-formyl-2'-deoxycytidine	1361013-62-8	C₃₈H₃₅N₃O₈	661.711
——	5'-O-(4,4'-dimethoxytrityl)-5-methoxycarbonyl-N4-acetyl-2'-deoxycytidine	1311141-24-8	C₃₄H₃₅N₃O₉	629.667
——	3'-(diisopropylcyanoethylphospino)-5'-(dimethoxytrityl)-4,5-(1,3-[3H,6H]oxazin-2-one)deoxycytidine	1257247-42-9	C₄₁H₄₈N₅O₉P	785.834
——	3'-(diisopropylamino-cyanoethoxyphosphino)-5'-(4,4'-dimethoxytrityl)-4-N-benzoyl-5-formyl-2'deoxycytidine	1361013-60-6	C₄₇H₅₂N₅O₉P	861.932
——	2-[2'-deoxy-3'-O-cyanoethyl-N,N'-diisopropylphosphoramidite-5'-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]pyrimido[4,5-c]isoquinoline-3,6(5H)-dione	——	C₄₆H₅₀N₅O₈P	831.905