丙二醇二辛酸酯/二癸酸酯 | 58748-27-9

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物 - 羧酸酯及其衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 丙二醇二辛酸酯/二癸酸酯
• 英文名称: decanoic acid;2-octanoyloxypropyl octanoate
• CAS: 58748-27-9
• 化学式: C39H76O8
• 分子量: 673.0
• InChiKey: UGTABSAUSFGUPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.61
• 重原子数：
  47
• 可旋转键数：
  33
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  127
• 氢给体数：
  2
• 氢受体数：
  8

制备方法与用途

功效与作用

丙二醇二辛酸酯/二癸酸酯在化妆品中皮肤调理剂和柔润剂使用，具有优良的乳化、分散、增溶、润滑能力。有轻微致粉刺的可能。

文献信息

• SKIN EXTERNAL PREPARATIONS AND COSMETICS
  申请人：Aoki Hirobumi

  公开号：US20100280111A1

  公开（公告）日：2010-11-04

  An object of the present invention is to provide skin external preparations and cosmetics which contain a branched acyl carnitine and have excellent formulation stability. A skin external preparation of the present invention includes a carnitine derivative represented by the following Formula (1) and/or a carnitine derivative salt represented by the following Formula (2), and an amphoteric surfactant. In Formula (1), R 1 and R 2 are each independently a C1-18 optionally branched, saturated or unsaturated aliphatic hydrocarbon group. In Formula (2), R 1 and R 2 are the same as in Formula (1), X − is a specific anion and Y + is a specific cation.

  本发明的一个目的是提供含有支链酰基肉碱并具有优异配方稳定性的皮肤外用制剂和化妆品。本发明的皮肤外用制剂包括以下式（1）所表示的肉碱衍生物和/或以下式（2）所表示的肉碱衍生物盐，以及一种两性表面活性剂。在式（1）中，R1和R2分别独立地是C1-18的可选支链、饱和或不饱和脂肪烃基。在式（2）中，R1和R2与式（1）中相同，X−是特定的阴离子，Y+是特定的阳离子。
• SKIN AGENT FOR EXTERNAL USE AND COSMETIC AGENT INCLUDING UBIQUINONE DERIVATIVE OR SALT THEREOF AND METHOD USING THE SAME
  申请人：Aoki Hirobumi

  公开号：US20100074879A1

  公开（公告）日：2010-03-25

  A skin agent for external use and a cosmetic agent are provided, by transdermal administration of which expected actions and effects of ubiquinone derivatives, salts thereof, ubiquinones and ubiquinols are effectively obtained. The skin agent for external use includes a ubiquinone derivative or a salt thereof as an active ingredient. The ubiquinone derivative is represented by the formula (1): wherein R 1 and R 2 are each a hydrogen atom or a phosphoric group, at least one of R 1 and R 2 is a phosphoric group, and n is an integer in the range of 1 to 9.

  提供了一种外用皮肤剂和化妆品剂，通过经皮给药，可以有效地获得辅酶Q衍生物、其盐、辅酶Q和辅酶QH的预期作用和效果。外用皮肤剂包括辅酶Q衍生物或其盐作为活性成分。辅酶Q衍生物由式（1）表示：其中R1和R2分别是氢原子或磷酸基团，R1和R2中至少有一个是磷酸基团，n是1到9范围内的整数。
• EMULSION PREPARATION FOR EXTERNAL APPLICATION TO SKIN AND COSMETIC PREPARATION
  申请人：Showa Denko K.K.

  公开号：EP2238970A1

  公开（公告）日：2010-10-13

  An object of the present invention is to provide emulsified skin external preparations and cosmetics which contain a branched acyl carnitine and have excellent emulsion stability. An emulsified skin external preparation according to the present invention includes 0.01 to 10% by mass of a carnitine derivative represented by the following Formula (1) and/or a carnitine derivative salt represented by the following Formula (2), and 0.01 to 20% by mass of a nonionic surfactant. In Formula (1), R1 and R2 are each independently a C1-18 optionally branched, saturated or unsaturated aliphatic hydrocarbon group. In Formula (2), R1 and R2 are the same as in Formula (1), X- is a specific anion and Y+ is a specific cation.

  本发明的一个目的是提供含有支链酰基肉碱且具有优异乳化稳定性的乳化皮肤外用制剂和化妆品。根据本发明的乳化皮肤外用制剂包括下列式（1）所表示的肉碱衍生物和/或下列式（2）所表示的肉碱衍生物盐，以及非离子表面活性剂，其质量百分含量分别为0.01至10%和0.01至20%。在式（1）中，R1和R2各自独立地是C1-18的可选支链、饱和或不饱和脂肪烃基。在式（2）中，R1和R2与式（1）中相同，X-是特定阴离子，Y+是特定阳离子。
• Slimming Skin External Preparation and Cosmetic Containing the Same
  申请人：Shibuya Akira

  公开号：US20070232698A1

  公开（公告）日：2007-10-04

  The invention provides a slimming skin external preparation and a cosmetic that contain a carnitine derivative having excellent skin affinity and percutaneous absorption properties and capable of enhancing the fat metabolism, and that can treat, reduce or prevent the obesity by functioning as a lipolytic agent to enhance the fat metabolism of general or local subcutaneous fat tissues. The slimming skin external preparation contains a particular carnitine derivative and preferably other slimming and skin-care ingredients.

  该发明提供了一种含有卡尼汀衍生物的减肥皮肤外用制剂和化妆品，该衍生物具有优异的皮肤亲和性和经皮吸收性能，并能够增强脂肪代谢，通过作为脂肪分解剂增强一般或局部皮下脂肪组织的脂肪代谢，从而能够治疗、减少或预防肥胖。该减肥皮肤外用制剂含有特定的卡尼汀衍生物，最好还包含其他减肥和护肤成分。
• WHITENING DERMATOLOGICAL PREPARATIONS
  申请人：Kamachi Harumi

  公开号：US20090240070A1

  公开（公告）日：2009-09-24

  Disclosed is a dermatological preparation that are safe and are excellent in inhibiting and removing skin pigmentation and in inhibiting skin roughness. A dermatological preparation comprising a tocopherol aminoalkylcarboxylate and/or a salt thereof, the tocopherol aminoalkylcarboxylate being represented by Formula (I): wherein R 1 is a hydrogen atom or a lower alkyl group; R 2 and R 3 are each independently a hydrogen atom or a methyl group; X is a cycloalkylene group of 3 to 6 carbon atoms; and n is 0 or 1.

  本发明涉及一种皮肤科制剂，其安全有效地抑制和去除皮肤色素沉着，并抑制皮肤粗糙度。该皮肤科制剂包括一种生育酚氨基烷基羧酸酯和/或其盐，所述生育酚氨基烷基羧酸酯由式(I)表示：其中，R1是氢原子或低碳基；R2和R3各自独立地是氢原子或甲基基团；X是3至6个碳原子的环烷基团；n为0或1。