3,6,8,8-tetramethyl-1,2,3,7,8,8a-hexahydro-3a,7-methano-azulen-4-one | 84752-97-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3,6,8,8-tetramethyl-1,2,3,7,8,8a-hexahydro-3a,7-methano-azulen-4-one
• 英文别名: 3,6,8,8-Tetramethyl-1,2,3,7,8,8a-hexahydro-3a,7-methano-azulen-4-on；Cedrenon；1,2,3,7,8,8a-Hexahydro-3,6,8,8-tetramethyl-4IH-3a,7-methanoazulen-4-one；2,6,6,8-tetramethyltricyclo[5.3.1.01,5]undec-8-en-10-one
• CAS: 84752-97-6
• 化学式: C₁₅H₂₂O
• 分子量: 218.339
• InChiKey: BGDCOEHXBFJKSF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2914399090

反应信息

• 作为反应物：
  描述：

  3,6,8,8-tetramethyl-1,2,3,7,8,8a-hexahydro-3a,7-methano-azulen-4-one 在 sodium acetate 、 乙酸酐 、 锌 作用下， 生成 3,5-diacetoxy-2,4,6-trimethylphenyl acetate
  参考文献：
  名称：

  Herzig; Wenzel, Monatshefte fur Chemie, 1914, vol. 35, p. 66

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 3,6,8,8-tetramethyl-1,2,3,7,8,8a-hexahydro-3a,7-methano-azulen-4-one
  参考文献：
  名称：

  A multivariate analysis of the association between social class of origin and current social class with self-rated general health and psychological health among 16-year-old Australians

  摘要：

  Abstract: Background: A recent review of international literature concludes that there is a relative absence of social class differentials in health in early youth. There is an absence of Australian studies on the effect of social class on the health of this age group. Aims: To examine the association between social class and health among 16‐year‐old Australians. Methods: The data on 1048 16‐year‐olds came from the fifth wave (1993) of the Australian Youth Survey conducted by the former Department of Employment, Education and Training. Outcome measures were self‐rated general health and psychological health (GHQ‐12). Binary logistic regression was used to analyse data. Results: Neither social class of origin nor current social class was associated with self‐rated general health or psychological health. Conclusion: The argument that social class inequalities in health exist in childhood, disappear during early youth, and reappear later appears to hold ground within the Australian context.

  DOI：

  10.1111/j.1445-5994.2000.tb04359.x

文献信息

• [EN] METHOD FOR THE MANUFACTURE OF α,β-UNSATURATED KETONES<br/>[FR] PROCÉDÉ DE FABRICATION DE CÉTONES À INSATURATION α, β
  申请人：SENSIENT FRAGRANCES S A

  公开号：WO2021213828A1

  公开（公告）日：2021-10-28

  A method for the manufacture of an α,β-unsaturated ketone, which method comprises oxidizing an alkene having -CH2- adjacent a carbon-carbon double bond to α,β-unsaturated ketone by passing air or oxygen through a solution of the hydrocarbon containing a catalyst consisting of N-hydroxyphthalimide (NHPI) and cobalt diacetate tetrahydrate at standard temperature and pressure during a period of at least 12 hours.

  一种制造α，β-不饱和酮的方法，该方法包括通过将空气或氧气通过含有N-羟基邻苯二甲酰亚胺（NHPI）和醋酸钴四水合物催化剂的烃溶液，在标准温度和压力下至少12小时的时间内将-CH2-邻近碳-碳双键的烯烃氧化为α，β-不饱和酮。
• METHOD FOR THE MANUFACTURE OF ALFA,BETA-UNSATURATED KETONES
  申请人：Sensient Fragrances S.A.

  公开号：EP3901128A1

  公开（公告）日：2021-10-27

  A method for the manufacture of an α,β-unsaturated ketone, which method comprises oxidizing an alkene having -CH2- adjacent a carbon-carbon double bond to α,β-unsaturated ketone by passing air or oxygen through a solution of the hydrocarbon containing a catalyst consisting of N-hydroxyphthalimide (NHPI) and cobalt diacetate tetrahydrate at standard temperature and pressure during a period of at least 12 hours.

  一种制造α，β-不饱和酮的方法，该方法包括在标准温度和压力下，使空气或氧气通过含有由 N-羟基邻苯二甲酰亚胺（NHPI）和四水合二乙酸钴组成的催化剂的碳氢化合物溶液至少 12 小时，将邻接碳碳双键具有-CH2-的烯氧化成α，β-不饱和酮。
• Semmler; Hoffmann, Chemische Berichte, 1907, vol. 40, p. 3525
  作者：Semmler、Hoffmann

  DOI：——

  日期：——
• Structure of the "symmetrical cedrone"
  作者：H. M. Fales、J. A. Beisler、J. V. Silverton、A. Penttila、D. H. S. Horn

  DOI：10.1021/ja00748a031

  日期：1971.9
• SILICONE COMPOUNDS
  申请人：The Procter & Gamble Company

  公开号：EP3649183A1

  公开（公告）日：2020-05-13