Glycyrrhizol A | 877373-00-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: Glycyrrhizol A
• 英文别名: 1-methoxy-2,8-bis(3-methylbut-2-enyl)-6H-[1]benzofuro[3,2-c]chromene-3,9-diol
• CAS: 877373-00-7
• 化学式: C₂₆H₂₈O₅
• 分子量: 420.5
• InChiKey: CBPFOSMNDISZLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  72.1
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES
  申请人：MitoPower, LLC

  公开号：US20200397807A1

  公开（公告）日：2020-12-24

  The disclosure provides nicotinamide riboside (NR), the reduced form of NR (NRH), nicotinic acid riboside (NAR), the reduced form of NAR (NARH), derivatives thereof, compositions thereof and uses thereof. The NR and NAR derivatives have improved stability and bioavailability compared to NR and NAR. NR, NRH, NAR, NARH, and derivatives thereof can increase cellular NAD + levels and enhance mitochondrial and cellular function and cell viability. Therefore, NR, NRH, NAR, NARH, and derivatives thereof, whether alone or in combination with one or more additional therapeutic agents (e.g., a mitochondrial uncoupler or/and a PARP inhibitor), are useful for treating mitochondrial diseases, mitochondria-related diseases and conditions, metabolic disorders, and other disorders and conditions.

  该披露提供烟酰胺核糖苷（NR）、烟酰胺核糖苷的还原形式（NRH）、烟酸核糖苷（NAR）、烟酸核糖苷的还原形式（NARH）、以及它们的衍生物、组合物和用途。与NR和NAR相比，NR和NAR的衍生物具有更好的稳定性和生物利用度。NR、NRH、NAR、NARH和它们的衍生物可以增加细胞NAD+水平，增强线粒体和细胞功能以及细胞存活能力。因此，NR、NRH、NAR、NARH和它们的衍生物，无论是单独使用还是与一个或多个额外治疗剂（例如线粒体解耦蛋白抑制剂和/或PARP抑制剂）结合使用，都可用于治疗线粒体疾病、与线粒体相关的疾病和症状、代谢紊乱以及其他疾病和症状。
• ACTIVE COMPOUND COMBINATIONS
  申请人：Bayer AG

  公开号：EP3701796A1

  公开（公告）日：2020-09-02

  The present invention relates to active compound combinations, in particular within a fungicide composition, which comprise (A) fluoxapiprolin and (B) at least one biological control agent and/or (C) at least one compound selected from insecticides, acaricides and nematicides. Moreover, the invention relates to compositions comprising such compound combination and to the use thereof as biologically active combinations, especially for control of harmful microorganisms, in particular oomycetes, in crop protection.

  本发明涉及活性化合物组合，特别是杀真菌剂组合物中的活性化合物组合，其中包括(A)氟氧吡咯林和(B)至少一种生物防治剂和/或(C)至少一种选自杀虫剂、杀螨剂和杀线虫剂的化合物。此外，本发明还涉及包含此类化合物组合的组合物，以及将其用作生物活性组合物，特别是在作物保护中用于控制有害微生物，尤其是卵菌。
• GRANULAR NEMATICIDE COMPOSITIONS
  申请人：Monsanto Technology LLC

  公开号：EP3818829A2

  公开（公告）日：2021-05-12

  Various granular agrochemical compositions comprising an agrochemical component comprising a 3,5-disubstituted-1,2,4-oxadiazole or a salt thereof and a particulate carrier, and at least about 2 % wt water.

  各种颗粒状农用化学品组合物，其中包含一种农用化学品成分，该成分由 3,5-二取代-1,2,4-噁二唑或其盐和一种颗粒载体以及至少约 2% wt 的水组成。
• Stable inoculant compositions and methods for producing same
  申请人：NOVOZYMES BIOAG A/S

  公开号：US10820594B2

  公开（公告）日：2020-11-03

  The present disclosure provides non-aqueous inoculant compositions and methods for enhancing the survival and/or stability of microbial spores in an inoculant composition. In some embodiments, inoculant compositions of the present disclosure comprise microbial spores, one or more dispersants, one or more dust suppressants and a solid non-aqueous carrier.

  本公开提供了用于提高微生物孢子在接种剂组合物中的存活率和/或稳定性的非水接种剂组合物和方法。在一些实施方案中，本公开的接种剂组合物包含微生物孢子、一种或多种分散剂、一种或多种粉尘抑制剂和固体非水载体。
• Polyhipes by interfacial step-growth polymerization
  申请人：Technion Research & Development Foundation Limited

  公开号：US10851218B2

  公开（公告）日：2020-12-01

  A polyHIPE-templated composition-of-matter afforded by interfacial polymerization, comprising a polymer of alternating residues of hydrophobic and hydrophilic monomers. The described composition-of-matter is characterized by an open-, quasi-closed- or a truly closed-cell microstructure, whereas the latter is capable of non-releasably or releasably encapsulating an organic or aqueous composition therein for extended periods of time, as well as various uses thereof.

  一种通过界面聚合法获得的聚 HIPE 模板物质组合物，由疏水单体和亲水单体交替残留的聚合物组成。所述物质组合物的特点是具有开孔、准闭孔或真正闭孔的微观结构，而后者能够以不可释放或可释放的方式将有机或水性组合物长时间封装在其中，并具有多种用途。