fraserinone A

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: fraserinone A
• 英文别名: 5,7-Dihydroxy-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-2,3-dihydrochromen-4-one；5,7-dihydroxy-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-2,3-dihydrochromen-4-one
• 化学式: C₂₁H₂₂O₆
• 分子量: 370.402
• InChiKey: DVOBXRXPMIWESL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  96.2
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  fraserinone A 在 盐酸 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以60%的产率得到5,7-Dihydroxy-3-(6-methoxy-2,3,3-trimethyl-2,3-dihydro-benzofuran-5-yl)-chroman-4-one
  参考文献：
  名称：

  Isoflavonoids in roots of sophora fraseri

  摘要：

  Six known phenolic compounds [sophoronol, sophoraisoflavanone A, maackiain, sophoracarpan B, calycosin and 2-(2',4'-dihydroxyphenyl)-5,6-methylenedioxybenzofuran], and a new is of lavanone were isolated from the roots of Sophora fraserii. The structure of the new compound, named fraserinone A, was shown to be 5,7,4'trihydroxy-5'-(1,1-dimethylallyl)-2'-metho by means of spectroscopic analysis.

  DOI：

  10.1016/s0031-9422(00)90868-9

文献信息

• Isoflavonoids in roots of sophora fraseri
  作者：Munekazu Iinuma、Masayoshi Ohyama、Toshiyuki Tanaka、Mervyn P. Hegarty、Elwyn E. Egarty

  DOI：10.1016/s0031-9422(00)90868-9

  日期：1993.12

  Six known phenolic compounds [sophoronol, sophoraisoflavanone A, maackiain, sophoracarpan B, calycosin and 2-(2',4'-dihydroxyphenyl)-5,6-methylenedioxybenzofuran], and a new is of lavanone were isolated from the roots of Sophora fraserii. The structure of the new compound, named fraserinone A, was shown to be 5,7,4'trihydroxy-5'-(1,1-dimethylallyl)-2'-metho by means of spectroscopic analysis.