3',4',5,7-Tetrahydroxyisoflavanone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 3',4',5,7-Tetrahydroxyisoflavanone
• 英文别名: 3-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
• 化学式: C₁₅H₁₂O₆
• 分子量: 288.25
• InChiKey: DYLLIDCIKLUGBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF
  申请人：Kaleido Biosciences, Inc.

  公开号：EP3071235A1

  公开（公告）日：2016-09-28
• GLYCAN COMPOSITIONS AND USES THEREOF
  申请人：Kaleido Biosciences, Inc.

  公开号：EP3334437A1

  公开（公告）日：2018-06-20
• COMPOSITE COMPRISING 3'-HYDROXYGENISTEIN AND USE FOR INHIBITION OF MELANOGENESIS
  申请人：BIO-JOURDENESS INTERNATIONAL GROUP CO., LTD.

  公开号：US20160338992A1

  公开（公告）日：2016-11-24

  A composite comprising 3′-hydroxygenistein and a use for inhibition of melanogenesis are revealed herein. An effective dose of 3′-hydroxygenistein is applied to skin for inhibition of tyrosinase activity and further inhibition of melanogensis, so that 3′-hydroxygenistein can be used in cosmetic composition.
• [EN] GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF<br/>[FR] COMPOSITIONS THÉRAPEUTIQUES DE GYLCANE ET PROCÉDÉS ASSOCIÉS
  申请人：KALEIDO BIOSCIENCES INC

  公开号：WO2016122889A1

  公开（公告）日：2016-08-04

  Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
• [EN] GLYCAN COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSITIONS DE GLYCANE ET LEURS UTILISATIONS
  申请人：KALEIDO BIOSCIENCES INC

  公开号：WO2017035412A1

  公开（公告）日：2017-03-02

  Compositions comprising glycan preparations suitable for local administration to non-gut sites containing mucosal tissue, e.g., oral cavity, nasal cavity and vagina are provided. Further provided are methods of using said glycan preparations.