(aR)-2'-methoxyvinaxanthone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: (aR)-2'-methoxyvinaxanthone
• 英文别名: 5,7-Diacetyl-6-(5-carboxy-6,7-dihydroxy-2-methoxy-4-oxochromen-3-yl)-2,3-dihydroxy-9-oxoxanthene-1-carboxylic acid
• 化学式: C₂₉H₁₈O₁₅
• 分子量: 606.453
• InChiKey: HYNJWQUNCFKEGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  44
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  252
• 氢给体数：
  6
• 氢受体数：
  15

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 (aR)-2'-methoxyvinaxanthone 生成 permethylated (aR)-2'-methoxyvinaxanthone
  参考文献：
  名称：

  A Biaryl Xanthone Derivative Having Axial Chirality from Penicillium vinaceum

  摘要：

  A new xanthone derivative having axial chirality was isolated from Penicillium vinaceum. Owing to the axial chirality, its structure, including absolute configuration, was determined by means of extensive spectroscopic data, such as UV, IR, MS, and 1D and 2D NMR spectra, and computational chiroptical methods. The new compound, (aR)-2'-methoxyvinaxanthone, has a structure containing two aromatic moieties with substituents hindering rotation about the biaryl axis. The compound gave positive results in a sea urchin egg test (Paracentrotus lividus) and a crown gall tumor on potato disks test (Agrobacterium tumefaciens).

  DOI：

  10.1021/np800020p

文献信息

• A Biaryl Xanthone Derivative Having Axial Chirality from <i>Penicillium vinaceum</i>
  作者：Tomáš Řezanka、Pavel Řezanka、Karel Sigler

  DOI：10.1021/np800020p

  日期：2008.5.1

  A new xanthone derivative having axial chirality was isolated from Penicillium vinaceum. Owing to the axial chirality, its structure, including absolute configuration, was determined by means of extensive spectroscopic data, such as UV, IR, MS, and 1D and 2D NMR spectra, and computational chiroptical methods. The new compound, (aR)-2'-methoxyvinaxanthone, has a structure containing two aromatic moieties with substituents hindering rotation about the biaryl axis. The compound gave positive results in a sea urchin egg test (Paracentrotus lividus) and a crown gall tumor on potato disks test (Agrobacterium tumefaciens).